376,932 results match your criteria: "Turkey; Koç University İşbank Center for Infectious Diseases (KUISCID)[Affiliation]"

Radiological risk assessment due to radon in bottled drinking water sold in Kahramanmaraş town, Turkiye.

Isotopes Environ Health Stud

March 2025

Department of Materials and Material processing, Vocational School of Technical Sciences, Kahramanmaras Sutcu Imam University, K. Maras, Turkey.

This research aimed to measure radon activity concentrations in bottled drinking water (BDW) samples consumed in Kahramanmaraş town, Turkiye. Also, to evaluate the health risk that may occur as a result of internal irradiation resulting from ingestion and inhalation of radon in BDW samples, the total annual effective dose equivalent (AEDE) for infants, children, and adults (1-2 y, 2-12 y, and > 17 y) and excess lifetime cancer risk (ELCR) for adults (> 17 y) had to be calculated. For these purposes, 32 water samples of different volumes belonging to 8 different commercial brands, representing a large part of the BDW consumed as drinking water and sold commercially in Kahramanmaraş were collected by purchasing from markets.

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Anagen effluvium is a rare adverse effect of methotrexate therapy, generally associated with high-dose regimens. We report a 12-year-old girl who developed abrupt hair loss 1 week after inadvertently taking methotrexate 15 mg daily for five consecutive days (total 75 mg), without other signs of systemic toxicity. Trichoscopic examination and trichogram findings confirmed methotrexate-induced anagen effluvium, and spontaneous hair regrowth occurred after 2 months.

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Background: The importance of subjective quality of life questionnaires in evaluating post-rhinoplasty outcomes and patient satisfaction is increasing.

Objective: This study aimed to measure the aesthetic and functional satisfaction of patients following septorhinoplasty using the Rhinoplasty Health Inventory and Nasal Outcomes (RHINO), Rhinoplasty Outcome Evaluation (ROE), and Nasal Obstructive Symptom Evaluation (NOSE) questionnaires.

Methods: This prospective study included 306 patients who underwent a primary open-technique septorhinoplasty.

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Objective: To assess the frequency of unrecognized myocardial infarction and identify additional ischemic conditions, as well as to evaluate the efficacy of cardiac magnetic resonance imaging (CMRI) in risk groups, comparing the imaging findings with electro-cardiographic (ECG) and laboratory data in patients with stage 5 chronic kidney disease, also known as end-stage renal disease.

Materials And Methods: This was a prospective single-center study involving 20 patients who were referred to our radiology department to undergo CMRI between June 2010 and December 2011. Resting left ventricular functions and (early and late) myocardial contrast enhancement were assessed in all patients.

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Background: The mental health and wellbeing of nurses, particularly pediatric nurses, have garnered attention due to the increased risk of mental health challenges associated with their demanding profession. These nurses are especially vulnerable, yet their mental wellbeing is often understudied.

Objective: This systematic review aims to identify and analyze key factors associated with mental health challenges among pediatric nurses and explore how these factors interact to influence their wellbeing.

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Artificial intelligence (ChatGPT) ready to evaluate ECG in real life? Not yet!

Digit Health

March 2025

Bahçeşehir Üniversite Hastanesi Medical Park Göztepe, İstanbul, Turkey.

Objective: This study aims at evaluating if ChatGPT-based artificial intelligence (AI) models are effective in interpreting electrocardiograms (ECGs) and determine their accuracy as compared to those of cardiologists. The purpose is therefore to explore if ChatGPT can be employed for clinical setting, particularly where there are no available cardiologists.

Methods: A total of 107 ECG cases classified according to difficulty (simple, intermediate, complex) were analyzed using three AI models (GPT-ECGReader, GPT-ECGAnalyzer, GPT-ECGInterpreter) and compared with the performance of two cardiologists.

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Early outcomes of left bundle branch area pacing in children.

Cardiol Young

March 2025

Department of Pediatric Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training & Research Hospital, University of Health Sciences, İstanbul, Turkey.

Objective: Left bundle branch area pacing is a recent technique gaining rapid acceptance due to its broader target area and excellent electrical parameters. The aim of this study was to demonstrate the feasibility of left bundle branch area pacing in children and share short-term results.

Materials And Methods: A retrospective study conducted at a single centre between December 2021 and April 2024 involved 19 children who underwent left bundle branch area pacing using Select Secure leads.

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The aim of this study is to investigate the rate, risk factors, causative microorganism distribution, and treatment outcomes of catheter-related bloodstream infection (CRBSI) in chronic hemodialysis patients undergoing treatment with a tunneled hemodialysis catheter. Data for all patients who underwent hemodialysis treatment with tunneled catheters at our center between January 2014 and January 2024 were retrospectively analyzed. A total of 171 patients were included in the study.

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IntroductionPeripheral artery disease (PAD) poses a growing clinical challenge due to an aging population, despite advances in treatment methods. Various scoring systems have emerged to predict high-risk patients, including the HALP (hemoglobin, albumin, lymphocyte, and platelet) score, known for predicting prognosis in cancers and stroke. This study assesses the HALP score's relation to lesion severity and long-term mortality in PAD patients.

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Background: Medium cut-off (MCO) dialyzers are designed to provide clearance of large-middle molecular weight uremic toxins and cytokines that are also responsible for the pathogenesis of sarcopenia.

Aim: To investigate the short- and long-term effects of MCO dialyzers on fat and muscle mass.

Methods: This single-center prospective, cross-over study includes 20 maintenance hemodialysis (MHD) patients treated with low-flux (LF) dialyzers.

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Can urticaria severity be used as a biomarker for transition from acute to chronic urticaria?

Pediatr Allergy Immunol

March 2025

Department of Pediatric Allergy and Immunology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.

Background: Acute urticaria usually resolves spontaneously; however, in some cases, it may progress to CSU. We aimed to investigate the underlying factors of AU in children and the clinical and laboratory factors affecting the progression of AU to CSU.

Methods: A prospective analysis was performed in 155 patients under 18 years of age who were diagnosed with AU and treated in our hospital.

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Objectives: To gain further understanding of current outcomes regarding urethroplasty for female urethral stricture disease.

Methods: The European Association of Urology Section of Genitourinary Reconstructive Surgeons formed the Female Reconstruction Group to enhance multicentric collaboration, and to generate more evidence on the most effective treatment options for female patients with recurrent urethral stricture. Patients were eligible for inclusion if they had a urethral stricture and had undergone one of three reconstructive procedures, namely ventral onlay flap (VOFU), ventral onlay graft (VOGU) or dorsal onlay graft (DOGU) urethroplasty.

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Background: Inborn errors of metabolism (IEMs) are inherited diseases causing significant morbidity and mortality, particularly in childhood. Liver transplantation (LT) can be curative or partially effective for these diseases. LT for IEMs has increased, making IEMs the second most common reason for pediatric LT after biliary atresia.

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Objective: To determine the effect of online sustainable nutrition education (SNE) on sustainable eating behaviors and anthropometric measurements in women.

Design: In the research, a pretest-posttest quasi-experimental design was used for groups that were subjected to two different trainings.

Sample: In the education group, 34 and in the control group, 51 women that between the ages of 19-50 years from six Women's Education and Culture Centers of Ankara Altındağ Municipality.

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Background/objectives: Hashimoto's thyroiditis (HT) is the most common autoimmune disease which lowers a patient's quality of life. Our study aimed to assess the association between Mediterranean lifestyle and anthropometric measurements in patients with HT.

Methods: This study was conducted with 120 female patients previously diagnosed with HT.

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Acute Cardiovascular Effects of Turkish Coffee Assessed by VO Test: A Randomized Crossover Trial.

Nutrients

February 2025

Department of Nutrition and Health Psychology, Faculty of Health Sciences, American University of Madaba, MR62+F79, Madaba 11821, Jordan.

Background: Turkish coffee (TC), a traditional unfiltered coffee preparation method, contains unique bioactive compounds due to its specific brewing process. While TC's cultural significance is well-documented, its acute physiological and psychological effects remain understudied.

Objectives: This randomized, controlled crossover trial investigated the acute effects of a standardized TC dose (3 mg caffeine/kg body weight) on metabolic and psychological parameters in healthy female university students (n = 52, age: 20.

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Nattokinase (NK), a serine protease with high thrombolytic activity, has significant potential for application in foods intended for special health benefits. However, the NK production in wild-type natto is relatively low. In this study, a high-yielding NK and genetically stable mutant strain ( JNC002.

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Medicinal plants and natural compounds have been considered alternative therapeutic options for counteracting postmenopausal disorders thanks to their different concomitant effects, including antioxidant and anti-inflammatory properties and the regulation of hormone activity. It is important to highlight that the efficacy of medicinal plants and natural compounds increases when used in combination, thus making the development of herbal formulations rational. Therefore, the present study aimed to evaluate the phytochemical and pharmacological properties of an innovative formulation consisting of resveratrol and water extracts from , , , and .

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In this study, the effect of oven and microwave roasting at different times on oil content, total phenol, flavonoid, fatty acids, phenolic components and mineral contents of purslane seeds was investigated. The total phenolic quantities of the purslane seeds roasted in the oven and microwave were characterized to be between 252.0 ± 1.

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Recently, the potential of recycled materials to improve the performance of concrete and other building materials has become an important research topic. It is known that various methods are applied to improve the tensile strength and energy absorption capacity of cementitious systems. One of the most common of these methods is the addition of fibers to the mixture.

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Enhancing Mechanical and Thermal Performance of Recycled PA6/PP Blends: Chain Extension and Carbon Fiber Reinforcement Synergy.

Materials (Basel)

February 2025

Polymer Technology Program, Department of Materials and Material Technologies, Yalova Vocational School, Yalova University, Yalova 77100, Turkey.

To develop novel materials through the recycling of waste polymers and to enhance their mechanical and thermal properties, composites were synthesized using chain extenders (CEs), compatibilizers (PP-g-MA), and short carbon fiber (CF) reinforcements within recycled polyamide 6 (rPA6) and polypropylene (rPP) blends. The recycling of waste polymers holds paramount importance in the context of environmental sustainability. This study investigates the role of additives in effectively improving the properties of recycled polymers.

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Lime-based mortars, frequently used in historic structures, are classified as hydraulic and non-hydraulic according to how they gain strength. In the past, various methods were used to improve the strength and durability properties of lime-based hydraulic mortars such as Khorasan mortar. Today, in studies carried out to increase the strength of lime-based mortars, the effects of binders, aggregates, and additives, which are the basic components of the mortar, are examined.

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Co-Design and Evaluation Protocol for the RECOVER Model of Care After Childhood Cancer Treatment.

Healthcare (Basel)

February 2025

Cancer and Palliative Care Outcomes Centre at Centre for Children's Health Research, Queensland University of Technology, Brisbane, QLD 4001, Australia.

Advances in diagnosis and treatment have significantly increased survival rates for childhood cancer, leading to a growing population of long-term survivors. However, these survivors face substantial physical and psychological sequelae that affect both the child and their family. We developed the RECOVER model of care to support childhood cancer survivors as they transition from the end of their planned treatment to survivorship, addressing the broader health and wellness needs beyond medical surveillance.

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Effects of Vinorelbine on M2 Macrophages in Non-Small Cell Lung Cancer.

Int J Mol Sci

March 2025

Department of Basic Oncology, Institute of Health Sciences, Ege University, Bornova 35100, Izmir, Turkey.

Tumor-associated macrophages (TAMs) significantly influence tumor progression and patient responses to conventional chemotherapy. However, the interplay between anti-cancer drugs, immune responses in the tumor microenvironment, and their implications for cancer treatment remains poorly understood. This study investigates the effects of vinorelbine on M2 macrophages in lung cancer and its capacity to modulate TAMs toward an M1 phenotype.

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Ovarian cancer is among the most lethal gynecologic malignancies, often diagnosed at advanced stages due to a lack of effective screening tools. Recent studies suggest that the platelet-to-lymphocyte ratio (PLR), an indicator of systemic inflammation, may serve as a potential biomarker for diagnosing and staging ovarian cancer. We conducted a systematic review and meta-analysis, adhering to PRISMA guidelines.

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