373,081 results match your criteria: "Turkey; Hacettepe University Transgenic Animal Technologies Research and Application Center[Affiliation]"
Clin Rheumatol
January 2025
Department of Pediatric Rheumatology, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey.
Introduction/objectives: The study aimed to determine whether in children with newly diagnosed juvenile idiopathic arthritis (JIA) hepatitis B surface antibody (anti-HBs) differs from healthy children and to see whether the revaccination is safe and effective under JIA treatment.
Methods: Patients who were followed up with a diagnosis of JIA between January 2020 and February 2024 were included. The control group consisted of healthy children matched for age and gender.
Clin Rheumatol
January 2025
Division of Pediatric Rheumatology and Nephrology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Objective: Chronic non-bacterial osteomyelitis (CNO) is a rare autoinflammatory bone disease associated with other chronic inflammatory diseases such as familial Mediterranean fever (FMF), juvenile idiopathic arthritis (JIA), spondylarthropathies, inflammatory bowel disease (IBD), and pyoderma gangrenosum. We aimed to describe the clinical and follow-up characteristics of patients with CNO and to compare findings between patients with and without comorbidities.
Methods: The clinical records of patients with CNO who were followed up in our pediatric rheumatology clinic between 2018 and 2023 were reviewed.
Background: Cytolytic vaginosis (CV) is a condition characterized by an increase in lactobacilli in the vaginal flora, causing complaints of discharge, itching, dyspareunia, and dysuria. Since there are no antimicrobials in the treatment protocols of CV, the diagnostic and therapeutic criteria of which were first defined by Cibley, differential diagnosis of CV from other vaginitis agents will prevent unnecessary use of antimicrobials and recurrent com-plaints. In our study, we aimed to determine the frequency of CV in patients presenting with vaginitis complaints and the diagnostic accuracy of the diagnostic criteria.
View Article and Find Full Text PDFCornea
January 2025
Department of Ophthalmology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey; and.
Purpose: To evaluate the effect of subconjunctival injection of dexpanthenol on corneal neovascularization and inflammation in rats with induced chemical burns.
Methods: This experimental study included 40 female albino Wistar rats. Chemical burns were induced in the right eye of all rats on the first day, and the left eye was used as a control.
J Perianesth Nurs
January 2025
Surgical Nursing Department, Faculty of Health Sciences, Bahcesehir University, Istanbul, Turkey.
Purpose: This original study aimed to examine the relationship of emotional intelligence and passion to decision-making in surgical nurses.
Design: It is a descriptive, relational study.
Methods: This study was conducted with 166 surgical nurses.
J Perianesth Nurs
January 2025
Surgical Nursing Department, Faculty of Health Sciences, Bahcesehir University, Istanbul, Turkey.
Purpose: To provide a structured macroscopic overview of the characteristics and advances in research related to the Enhancing Recovery after Surgery (ERAS) protocol.
Design: A bibliometric analysis.
Methods: Web of Science was selected as the search engine for the bibliometric analysis study, and data up to January 25, 2024 were included in the scan.
Neuro Oncol
January 2025
Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Background: Despite advances in our understanding of the molecular underpinnings of meningioma progression and innovations in systemic and local treatments, recurrent meningiomas remain a substantial therapeutic challenge. The objective of this systematic review and meta-analysis is to provide a historical baseline, contemporary analysis, and propose a "rate of probable interest" to inform future clinical trial design and development on behalf of the RANO meningioma group.
Methods: PubMed, ClinicalTrials.
Turk J Pediatr
December 2024
Department of Plastic Reconstructive and Aesthetic Surgery, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Background: Any impediment to the development of midline structures i.e. hypothalamus, pituitary and oral cavity may cause anatomical and functional issues.
View Article and Find Full Text PDFClin J Pain
January 2025
Associate Professor, Department of Anesthesiology and Reanimation, Istanbul Marmara University Hospital, Istanbul, Turkey.
Objectives: After cesarean, optimal analgesia is important for early mobilization, mitigating thromboembolic risks, and mother-infant communication. Our study aims to compare the postoperative analgesic effects of intrathecal morphine (ITM) and Erector Spinae Plane Block (ESPB) in elective cesarean section under spinal anesthesia.
Methods: 82 patients were randomized into ESPB and ITM groups.
Clin Dysmorphol
December 2024
Department of Pediatrics, Kirikkale University Medical School, Kirikkkale, Turkey.
Clin Dysmorphol
December 2024
Department of Pediatric Genetics.
Introduction: Spondyloepimetaphyseal dysplasia with joint laxity type 1 (SEMD-JL1) is an extremely rare skeletal dysplasia belonging to a group of disorders called linkeropathies. It is characterized by skeletal and connective tissue abnormalities. Biallelic variants in genes encoding enzymes that synthesize the tetrasaccharide linker region of glycosaminoglycans lead to linkeropathies, which exhibit clinical and phenotypic features that overlap with each other.
View Article and Find Full Text PDFMiddle East J Dig Dis
October 2024
Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Fournier gangrene is a rare but severe complication of ulcerative colitis, characterized by necrotizing fasciitis affecting the genital and perineal regions. We present a case of a 53-year-old man with a history of ulcerative colitis and cytomegalovirus (CMV) colitis who developed Fournier gangrene, an exceptionally uncommon occurrence in this patient population. The patient initially presented with intense pain, swelling, and skin discoloration in the genital area, accompanied by systemic symptoms, including fever.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Chemistry, Faculty of Science, University of Maragheh P.O Box 55181-83111 Maragheh Iran.
In this study, we present the design, synthesis, and utilization of a covalent triazine framework (CTF) formed by the condensation of , , -tris(4-(aminomethyl)benzyl)-1,3,5-triazine-2,4,6-triamine and 2,4,6-tris(4-formylphenoxy)-1,3,5-triazine on which silica is immobilized (TPT-TAT/silica) as an innovative catalyst for porphyrins synthesis. Under solvothermal conditions, the condensation of triamine and trialdehyde precursors led to the formation of a covalent triazine framework (CTF) with a high nitrogen content. The resulting CTF is characterized by its extensive porosity and elevated nitrogen levels, which are critical for the creation of catalytic active sites.
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
Department of Chemical Engineering, Ataturk University, 25240 Erzurum, Turkey.
The combination of plasmonic metals and MXene, as a new and interesting member of the 2D material class, may provide unique advantages in terms of low cost, versatility, flexibility, and improved activity as an ideal surface-enhanced Raman spectroscopy (SERS) platform. Despite the recent progress, the present studies on the utilization of plasmonic metal/MXene-based SERS systems are quite limited and thereby benefits of the extraordinary properties of this combination cannot be realized. In this study, for the first time, we propose layer-by-layer (LbL) thin films of TiC MXene and gold nanoparticles (AuNPs) as a robust SERS platform (TiC/AuNPs).
View Article and Find Full Text PDFAnticancer Agents Med Chem
January 2025
Department of Biology, Faculty of Science, Atatürk University, Erzurum, Turkey.
Introduction/objective: Several nutraceuticals, food, and cosmetic products can be developed using royal jelly. It is known for its potential health benefits, including its ability to boost the immune system and reduce inflammation. It is rich in vitamins, minerals, and antioxidants, which can improve general health.
View Article and Find Full Text PDFAnticancer Agents Med Chem
January 2025
Department of Medical Biochemistry, Faculty of Medicine, Gaziantep University, 27410, Gaziantep, Turkey.
Background: The lung cancer is the leading cause of death worldwide. Although methods such as surgery, chemotherapy, radiotherapy, and immunotherapy are used for treatment, these treatments are sometimes inadequate. In addition, the number of chemotherapeutic agents used is very limited, and it is very important to use new natural agents that can increase the effect of these methods used in treatment.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut, USA.
In the human body, bioelectric cues are crucial for tissue stimulation and regeneration. Electrical stimulation (ES) significantly enhances the regeneration of nerves, bones, cardiovascular tissues, and wounds. However, the use of conventional devices with stimulating metal electrodes is invasive and requires external batteries.
View Article and Find Full Text PDFJ Sci Food Agric
January 2025
Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.
Background: Determining the optimum water absorption capacity of gluten-free flours for an improved breadmaking process has been a challenge because there is no standard method. In the present study, large amplitude oscillatory shear (LAOS) tests were performed to explore the impact of different levels of added water on non-linear viscoelastic response of soy flour dough in comparison to wheat flour dough at a consistency of 500 BU.
Results: Among the LAOS parameters, large strain modulus (G') and large strain rate viscosity (η') were found to better probe the impact of added water amount on non-linear viscoelastic properties of soy flour dough.
J Pediatr Orthop
January 2025
Department of Orthopaedics and Traumatology, Hacettepe University.
BMC Health Serv Res
January 2025
Balikesir Ataturk City Hospital, PM&R Clinic, Balikesir, Turkey.
Health service policies are evolving into qualified health care providing best possible outcomes as well as focused on patient satisfaction. Hence the qualification valued health care includes patient satisfaction measurements, it is suggested to get feedbacks during the assessment of outcomes from the patient's perspective. Aging of the world population accelerates demand on rehabilitation medicine which means recovering impairments so is directly related with quality of life.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Nutrition and Dietetics, Kutahya Health Sciences University School of Health Sciences, Kütahya, Turkey.
Background: This study was conducted to identify the impacts of the healthy plate model workshop on 4th-graders nutrition knowledge, behaviors, and habits.
Methods: The study was conducted from March to June 2023 in the Uskudar district of Istanbul, involving 102 children (50% girls) with a mean age of 10.2 ± 0.
BMC Med Educ
January 2025
Department of Didactics of Musical, Plastic and Corporal Expression, Faculty of Education Sciences, University of Granada, Granada, Spain.
Background: Motivation is a variable that directly influences task orientation. Within the motivational sphere, the motivational climate determines whether a task is performed with an intrinsic or extrinsic.
Purpose: It has been observed that depending on motivational orientations, anxiety levels and task performance can be increased.
BMC Gastroenterol
January 2025
Independent Researcher, İzmir, Turkey.
Background: Small-bowel angioectasia is commonly diagnosed and managed using double-balloon enteroscopy; however, rebleeding rates can vary significantly. This study aimed to identify and evaluate the clinical predictors of rebleeding in patients with small-bowel angioectasia.
Methods: This retrospective study focused on adult patients who underwent endoscopic management for small bowel vascular lesions (SBVLs).
BMC Geriatr
January 2025
Faculty of Medicine, Department of Geriatric Medicine, Gazi University, Ankara, 06560, Turkey.
Background: Chronic inflammation is increasingly recognized as a crucial contributor to sarcopenia pathogenesis, but accurate diagnosis remains a challenge.
Aim: Our study aims to investigate the relationship between sarcopenia and the Systemic Immune-Inflammation Index (SII), a comprehensive indicator of inflammation.
Methods: This cross-sectional study enrolled 632 patients.
Oral Radiol
January 2025
Department of Software Engineering, Faculty of Engineering, Muğla Sıtkı Koçman University, Muğla, 4800, Turkey.
Objectives: Pulp stones are ectopic calcifications located in pulp tissue. The aim of this study is to introduce a novel method for detecting pulp stones on panoramic radiography images using a deep learning-based two-stage pipeline architecture.
Materials And Methods: The first stage involved tooth localization with the YOLOv8 model, followed by pulp stone classification using ResNeXt.