Hybrid Modification of Wheat Bran Using Microbial Processing and Ultrasound: Enhancements in Bran Composition and Bread Quality.

This study investigates the effects of microbial bioprocessing (MB), ultrasound treatment (UT), and their combined application (hybrid method, HM) on the functional and nutritional enhancement of wheat bran (WB) and its impact on bread quality. MB was performed by using with LABE 32 (MB32) and LABE 29 (MB29). MB32 significantly increased soluble dietary fiber (SDF) and reduced phytic acid content by up to 25.

Exploring Moral Distress, Related Factors and Coping in Emergency Nurses: A Mixed Method Study.

Aim: To determine emergency nurses with moral distress level, related factors and coping.

Design: This is a mixed-methods study which included quantitative and qualitative approaches.

Methods: In quantitative phase, surveys were completed to 252 emergency nurses, while in the qualitative phase, semi-structured interviews were conducted with 23 nurses.

The relationship between night eating behavior, gastrointestinal symptoms, and psychological well-being: insights from a cross-sectional study in Türkiye.

Background: This cross-sectional study aimed to address the gap in understanding how night eating behavior impacts gastrointestinal health and psychological well-being in adult populations.

Method: This descriptive and cross-sectional study was conducted with 1372 adults aged 19-65 between September 2023 and November 2023. The research data were collected with the help of a web-based survey form (Google form) created by the researchers using the snowball sampling method.

Mechanical analysis of 3D printed dental restorations manufactured using different resins and validation with FEM analysis.

Purpose: The aim of this study was to compare the wear and fracture resistance of single crowns produced from newly developed 3D printer resins used to produce permanent crowns and currently used composite CAD/CAM discs, after being thermomechanically aged in a chewing simulator.

Materials And Methods: A total of 112 stainless steel die models simulating mandibular left first molars were produced, 8 for each group. Single crowns were produced from 3 different discs (Grandio Voco [GR], breCAM HIPC [HC], and Shofu HC [SF]) by CAD/CAM milling method and manufactured from from 4 different permanent composite resins (Nexdent C&B MFH [ND], Permanent Bridge Saremco [PB], VarseoSmile Crownplus [VSC], and Şenertek P-Crown [PC]) using the 3D printing method.

Evaluation of the effect of dental caries, oral hygiene, and treatment need on oral health-related quality of life among Turkish orphan children and adolescents.

Background: The oral and dental health and related quality of life of orphan children and adolescents-who are considered a vulnerable population-are critical for both individual and public health.

Objectives: This study aimed to investigate the status of the dental caries, oral hygiene, and dental treatment needs among a group of Turkish male orphan children and adolescents, as well as their impact on oral health-related quality of life.

Methods: A total of 112 orphan children and adolescents aged between 9 and 17 years living in a residential care facility in Istanbul, Türkiye, were involved in this cross-sectional study.

Evaluation of stress patterns in teeth with endodontic treatment and periapical lesions as abutments for fixed prosthesis: a finite element analysis study.

Background: Examining stress distributions in abutment teeth with periapical lesions is essential for understanding their biomechanical impact on dental structures and tissues. This study uses finite element analysis (FEA) to evaluate these stress patterns under occlusal forces, aiming to enhance treatment strategies and prosthetic designs.

Methods: Three FEA models were created: a healthy mandibular premolar (Model 1), a premolar with a single crown and a lesion repaired using a fiber-post (Model 2), and 3) a premolar with a lesion repaired using fiber-post to support a four-member bridge (Model 3).

Effect of antacid gastric syrups on surface properties of dental restorative materials: an in vitro analysis of roughness and microhardness.

Objectives: The aim of this in-vitro study was to evaluate the effects of antacid gastric syrups on the surface roughness and microhardness of restorative dental materials.

Materials And Methods: Three different composite resins, nanohybrid, microhybrid and giomer, and four antacid gastric syrups were used in the study. A total of 150 samples were obtained by preparing 50 (10 mm x 2 mm) disk-shaped samples of each composite type.

The effect of preoperative deep breathing exercise with incentive spirometer initiated in the preoperative period on respiratory parameters and complications in patients underwent open heart surgery: a randomized controlled trial.

Background: Incentive spirometer is used in lung expansion therapy to maintain alveolar patency and improve pulmonary volumes in postoperative cardiac surgical patients. Deep breathing exercises with an incentive spirometer significantly reduce the development of postoperative pulmonary complications after open-heart cardiac surgery.

Aim: To determine the effect of deep breathing exercises with an incentive spirometer initiated in the preoperative period on respiratory parameters and complications in patients who underwent open-heart surgery.

Analyse of patient characteristics and aetiological causes of enterocutaneous fistulas and their impacts on in-hospital mortality: a ten-year retrospective cohort study.

Introduction: This study aimed to compare patient characteristics according to the primary aetiology including gunshot wounds in inpatient individuals diagnosed with enterocutaneous fistula (ECF) or enteroatmospheric fistula (EAF) and to evaluate the impacts of these characteristics on all-cause in-hospital mortality.

Methods: This is a single-centre hospital-based retrospective cohort study conducted with adult patients who were hospitalised for treatment of ECF or EAF. The patients were allocated to three study groups according to their primary aetiology (surgery-related group, gunshot-related group and other-cause group).

Evaluation of gingival phenotype: the role of gingival thickness measurements from different vertical gingival levels.

Objectives: This study aimed to accurately assess the gingival phenotype by comparing the mean gingival thickness (GT) measured at various levels with a single-point GT measurement.

Materials And Methods: Fifty participants were divided into thin and thick gingival phenotype groups according to two different classifications. The first classification was based on the GT measured at the base of the gingival sulcus (GT1), whereas the second classification was based on the mean of the GT (GTm) measured at the base of the gingival sulcus (GT1 point) and 1 mm apical (GT2 point) and 2 mm apical to the base of the gingival sulcus (GT3 point).

Examination of heavy metal concentrations and their interaction with anthropogenic sources in Ermenek Dam Lake (Turquoise Lake).

This study aims to determine the spatial distribution of heavy metal pollution in Ermenek Dam Lake, water quality assessment and pollution sources. For this purpose, samples were taken 6 times a year from 12 points determined in 2024. Physico-chemical parameters and heavy metals were analyzed in the study.

Outcomes of cerclage wiring for intraoperative calcar fractures in cementless hemiarthroplasty in older patients with femoral neck fractures.

Background: Cementless hip hemiarthroplasty is one of the options for the treatment of osteoporotic femoral neck fractures. Intraoperative periprosthetic femoral calcar fractures sometimes occur during the surgery, and the use of cerclage wiring to maintain the position and stability of the femoral stem and prevent the progression of the fracture. This study examines the outcomes of cerclage wiring to treat intraoperative periprosthetic calcar fractures in cementless hip hemiarthroplasty in osteoporotic femoral neck fractures.

Patterns of balancing and compensating primary tooth extractions among paediatric dentists.

Introduction Balancing and compensating extractions (BCEs) of primary teeth aims to minimise the development of more severe malocclusions and reduce the need for subsequent complex orthodontics.Purpose To assess the demographics, practice characteristics and clinical preferences of United Kingdom paediatric dentists for BCEs of primary teeth.Methods All members of the British Society of Paediatric Dentistry were sent an electronic questionnaire.

Simultaneous evaluation of restless leg syndrome, neuropathic pain, disease activity, and quality of life in patients with Takayasu arteritis: a cross-sectional study.

We aimed to investigate the frequency of restless legs syndrome (RLS) and neuropathic pain (NeP) in patients with Takayasu arteritis (TAK), and their relationship with disease activity, and quality of life (QoL). In this prospective case-control study, we evaluated 30 patients with TAK and 28 healthy subjects. Demographic, clinical, and current treatment-related data were also recorded.

Influence of different priming treatments on germination potential and seedling establishment of four important hemp (Cannabis sativa L.) cultivars.

Medicinal hemp (Cannabis sativa L.) is gaining popularity due to its natural products with potential therapeutic properties, and its cultivation has recently been initiated in developing countries such as Turkey, Iran, India, and Pakistan. The crop is primarily grown using feminized seeds or popular varieties to achieve higher cannabidiol (CBD) yields, with seeds costing approximately $5-10 each.

The interface of depression and diabetes: treatment considerations.

This state-of-the-art review explores the relationship between depression and diabetes, highlighting the two-way influences that make treatment challenging and worsen the outcomes of both conditions. Depression and diabetes often co-occur and share genetic, lifestyle, and psychosocial risk factors. Lifestyle elements such as diet, physical activity, and sleep patterns play a role on the development and management of both conditions, highlighting the need for integrated treatment strategies.

Association between frailty and specific comorbidities on oncological outcomes in metastatic hormone-sensitive and castration resistant prostate cancer.

Objective: Demographic changes will lead to higher proportions of metastatic hormone-sensitive (mHSPC) and castration resistant metastatic prostate cancer (mCRPC) patients with higher frailty index and multiple comorbidities.

Materials And Methods: We relied on an institutional tertiary-care database to explore the effect of frailty (Eastern Cooperative Oncology Group [ECOG]), as well as cardiovascular (CVD) and secondary malignancy (SecCa) comorbidities on overall survival (OS) and time to mCRPC in mHSPC and OS in mCRPC patients with Kaplan-Meyer estimates and Cox regression models.

Results: Of 802 mHSPC patients, 61% were ECOG0 vs.

Assessment of Organ Donation Knowledge and Attitudes Among Patients Visiting the Nephrology Outpatient Clinic at a Tertiary Healthcare Facility.

This study aims to assess the knowledge levels, attitudes, and influencing factors related to organ donation among patients who visited the Nephrology outpatient clinic. This descriptive and cross-sectional research had 269 participants. Research data were collected utilizing a three-part questionnaire.

Microscopic and molecular studies of bovine Babesiosis in Sulaymaniyah, Iraq.

Bovine Babesiosis, a tick-borne disease that causes major economic loss in cattle farms, is caused by Babesia species. The diagnosis of the disease is suspected through clinical features (e.g.

Hemosporidian infection in free-living Cathartes aura (Linnaeus, 1758) in the Amazon biome, Pará State, Brazil: Parasitological, molecular, hematological, and biochemical analyses.

Hemosporidians are intracellular pathogens that infect a range of endothermic and ectothermic hosts and are transmitted by dipteran vectors. These parasites are grouped into four families: Haemoproteidae, Plasmodiidae, Leucocytozoidae, and Garniidae, with the genera Haemoproteus, Plasmodium, and Leucocytozoon being the most common in birds. Therefore, the objectives of this study were to detect the infection frequency of hemosporidians and to perform hematological and biochemical analyses in free-living turkey vultures (Cathartes aura) in the Amazon biome, Brazil.

Detection of selected vector-borne pathogens in domestic animals, ectoparasites, and their owners in a rural community in Southwest Guatemala.

Vector-borne pathogens, which are transmitted by blood-feeding arthropods to animals and people, are common in tropical regions where, combined with economic factors, can cause significant public health burden. A community-level study was undertaken in southwestern Guatemala to assess the presence of vector-borne pathogens in blood samples from humans (n = 98), their animals (n = 90), and ectoparasites (n = 83) over a period of 2 weeks. Human capillary blood was collected from participant's index finger, and animal venous blood (chickens, pigs, dogs, and cats) was collected from the jugular or cephalic veins at the enrollment period of a concurrent study.

Mechanical thrombectomy in elderly stroke patients with low ASPECTS: insights from STAR.

Background: The elderly population (≥80 years) were underrepresented in recent trials of endovascular thrombectomy (EVT) for anterior circulation large vessel occlusion acute ischemic stroke (LVO-AIS) with low Alberta Stroke Program Early CT Score (ASPECTS) (≤5).

Methods: This study analyzed data from a prospectively maintained database of 37 thrombectomy centers. The primary cohort of the study comprised patients with LVO-AIS aged ≥80 who underwent EVT with ASPECTS≤5 from 2013 to 2023.

Burden and mortality of breast cancer attributed to diabetes and smoking in women: a secondary analysis based on Global Burden of Disease 2019 in North Africa and the Middle East.

Background: Breast cancer (BC) is the second most common cancer in the world. This study aimed to investigate the burden of BC due to some risk factors in the Middle East and North Africa (MENA) countries from 1990 to 2019.

Methods: This study is a secondary analysis based on the Global Burden of Disease 2019 data.

Lorlatinib Induced Blindness: A Rare Entity.

Lorlatinib is a central nervous system (CNS) penetrant third generation tyrosine kinase inhibitor (TKI) approved for the first line management of metastatic non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) rearrangement [1] which accounts for 3-5% of NSCLC cases [2]. The most commonly reported side effects include hyperlipidemia, edema, peripheral neuropathy and CNS effects [2]. While ocular side effects such as photopsia, blurred vision, vitreous floaters and diplopia have been documented with another ALK TKI, crizotinib, there are few reports of such effects with lorlatinib [3].