Enhanced Transepithelial Riboflavin Delivery Across the Cornea Using Magnetic Nanocarriers.

Keratoconus is a progressive corneal ectasia characterized by irregular astigmatism, leading to corneal scarring and decreased vision. Corneal cross-linking (CXL) is the standard treatment to halt disease progression, but its effectiveness in transepithelial (epithelium-on, epi-on) approaches is limited by the low permeability of the corneal epithelium to riboflavin (Rb). This study aimed to enhance transepithelial Rb penetration in bovine corneas using Rb-modified tannic acid-coated superparamagnetic iron oxide nanoparticles (Rb-TA-SPIONs) under an external magnetic field.

Effect of laparoscopic cholecystectomy on plasma levels of EETs, arachidonic acids derived lipid mediators.

Background: Epoxyeicosatrienoic acids (EETs) are closely associated with lipoprotein metabolism, and changes in lipid profiles potentially affect their levels and functions. Given the alterations in lipid metabolism after cholecystectomy, this study aimed to investigate the levels of four EET regioisomers (free and esterified) and lipid profiles in patients with cholelithiasis after laparoscopic cholecystectomy (LC) and explore correlations between these parameters.

Methods: This prospective study involved 40 patients with symptomatic cholelithiasis who underwent LC.

Validation of a Pretransplant Risk Prediction Model for Early Allograft Dysfunction After Living-donor Liver Transplantation.

Background: Early allograft dysfunction (EAD) affects outcomes in liver transplantation (LT). Existing risk models developed for deceased-donor LT depend on posttransplant factors and fall short in living-donor LT (LDLT), where pretransplant evaluations are crucial for preventing EAD and justifying the donor's risks.

Methods: This retrospective study analyzed data from 2944 adult patients who underwent LDLT at 17 centers between 2016 and 2020.

The effects of maternal body weight on iodine concentration in breast milk and cord blood and infant growth.

Breast milk (BM) is the only source of iodine and bioactive compounds that influence growth and development in infants. The content of BM may be influenced by maternal body mass index (BMI). The aim of this study was to investigate the effect of maternal weight on BM and cord blood iodine concentrations, growth-related hormones, infant anthropometric measurements.

Comparison of the risk scoring systems in long term restenosis due to percutaneous interventions to the superficial femoral artery.

Percutaneous superficial femoral interventions remain the preferred method of treatment for superficial femoral artery (SFA) disease. Nevertheless, long term restenosis continues to be a major limitation of percutaneous interventions. In this context, the objective of this study is to compare the efficacies of CHA2DS2-VASc, CHA2DS2-VASc-HS, ATRIA, ATRIA-HSV, and HATCH risk scoring systems in predicting long-term (5 years) restenosis due to percutaneous interventions to the superficial femoral artery.

Analysis of pediatric hand injuries in a tertiary care children's hospital.

Pediatric hand traumas are common injuries in childhood. The incidence and type of injury vary with age. In our country, there are only two publications in which only crush is examined in etiology.

Investigating the effect of freezing method, voltage gradient, and probe type on quality characteristics of Turkey meat during the ohmic thawing process.

This research addresses the gap in efficient thawing methods by investigating the effects of ohmic thawing variables and freezing methods on the thawing speed and quality attributes of ground turkey breast, aiming to identify the optimal ohmic thawing method and compare it with traditional air and water thawing techniques. The variables for ohmic thawing consisted of voltage gradient (10, 15, and 20 V/cm), freezing method (Snap (rapid freezing of samples in liquid nitrogen at -210 °C), -70, and -20 °C), and probe type. The results showed that the snap-freezing method demonstrated superior functional and quality characteristics.

Investigation of sexual life and perceived spousal support in female recipients after kidney transplantation.

Introduction: End-stage renal failure has negative effects on sexual life, and solid kidney transplantation helps to recovery in sexuality. However, recovery in sexual life progresses slowly, and female recipients may need spousal support during this process. To examine the perceived spousal support and sexual lives of female kidney recipients in the aim of this study.

Evaluation of sociodemographic, clinical and forensic medical characteristics of juvenile delinquents in Turkey.

It is accepted all over the world that children whose biological, psychological, cognitive, moral and social development processes are ongoing and whose value judgments are not sufficiently developed should not be punished or that punishment reductions should be applied. This study retrospectively analyzed the variables in a Turkish sample of 315 cases in which the criminal responsibility of children (83.5% boys and 16.

Evaluation of hepatic steatosis in obese children and adolescents using immune-inflammatory markers and shear wave elastography.

Aim: To investigate the changes in liver stiffness and immune-inflammatory markers associated with obesity and the degree of hepatic steatosis in obese children and adolescents.

Methods: A total of 76 obese children and adolescents aged 6-18 years, with body mass index percentiles >95th, were included in the study. Patients with metabolic syndrome, diabetes mellitus, and chronic liver disease were excluded.

The Effect of Task Cognitive Difficulty on Perceptual-Cognitive Indicators: Evidence on the Relationship Between Challenge Point Framework (CPF) and Cognitive Development in Table Tennis Beginners.

Introduction: Motor learning, in addition to influencing the practice of physical activity, affects cognitive skills related to prediction and decision. One key principle in sports training is designing exercise programs that optimize cognitive-motor performance, based on the Challenge Point Framework (CPF). The aim of this study is to investigate the effect of different levels of work difficulty on cognitive-perceptual indicators in table tennis beginners.

Endoscopic transcanal butterfly cartilage myringoplasty outcome; which parameters affect long-term results?

Background: Endoscopic transcanal butterfly cartilage myringoplasty is a prominent procedure because surgeons can perform this operation without elevating the transmeatal flap.

Objective: To evaluate factors that affect endoscopic butterfly cartilage myringoplasty regarding graft success and hearing improvement and determine long-term outcomes.

Materials And Methods: This study included 86 patients who underwent surgery.

The TDQ-60 Tr-a Picture-Naming Test to Assess Anomia in Turkish Adults and the Elderly: Normative Data and Validation Study in Alzheimer's Disease and Mild Cognitive Impairment.

Objective: Anomia is defined by difficulty in retrieving content words like nouns and verbs from long-term memory, independent of any impairments related to articulatory movements or motor speech execution. The tools for measuring picture naming, the conventional method for assessing anomia, are very limited in Turkey. The aim of this study was to adapt the Test de Dénomination de Québec-60 images/Quebec picture-naming test-60 pictures (TDQ-60), a color picture-naming test for adults and the elderly into Turkish, establish its validity, and develop normative data adapted to the Turkish population to address this gap.

Midterm to Long-term Follow-up After Limited Saucerization of a Discoid Lateral Meniscus: Radiological and Functional Outcomes With Age-Dependent Variations.

Background: A discoid lateral meniscus (DLM) is the most common meniscus variant and is commonly treated with arthroscopic saucerization. There are mixed data regarding long-term results after surgery, especially in terms of radiological parameters.

Purpose/hypothesis: The aim was to evaluate the functional and radiological results of patients who underwent arthroscopic saucerization for a symptomatic DLM.

The role of intrinsic spirituality, emotion dysregulation, and resilience on post-traumatic stress disorder symptoms in university students who survived earthquake.

Purpose: The study aimed to explore the relationship between intrinsic spirituality, emotion dysregulation, resilience, and PTSD in Turkish university students who were earthquake survivors. In addition, the validity and reliability of the Brief Emotion Dysregulation Scale (BEDS) were evaluated among Turkish university students who were earthquake survivors.

Methods: A sample of 651 Turkish university students who were earthquake survivors participated in an online survey distributed via WhatsApp, completing the Intrinsic Spirituality Scale (ISS), the Brief Emotion Dysregulation Scale (BEDS), the Brief Resilience Scale (BRS), and the Post-Traumatic Stress Disorder Checklist for DSM-5.

Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis.

Background: Surgical site infections (SSIs) are the most common postoperative complications after cesarean section (CS), with increased mortality, prolonged hospital stays, and increased healthcare costs.

Objective: To systematically estimate the global incidence and identify the risk factors associated with SSI, focusing on the variation between high- and low-income countries.

Search Strategy And Selection Criteria: Observational studies reporting on the incidence of SSI after CS were systematically searched in PubMed, Embase and SCOPUS.

Exploration of cognitive flexibility and emotion recognition in adolescents with eating disorders.

Objectives: This study compared cognitive flexibility (CF) and emotion recognition (ER) in adolescents with eating disorders (ED) to a healthy group.

Methods: Forty healthy individuals aged 12-18 years with no psychiatric diagnosis and 46 patients diagnosed with anorexia nervosa (AN), bulimia nervosa (BN), or binge eating disorder (BED) according to DSM-5 criteria participated. CF was assessed using the Cognitive Flexibility Scale (CFS), Stroop Test, and Berg Card Sorting Test (BCST), while ER was evaluated using the test of perception of affect via nonverbal cues.

Turkish validity and reliability study of the psychological food involvement scale: PFIS-TR.

Background: This study aimed to adapt the Psychological Food Involvement Scale (PFIS) to Turkish culture and test its validity and reliability. The PFIS measures individuals' psychological, emotional, and social relationships with food, which significantly impact eating behaviors and health.

Methods: The study was conducted with 478 participants aged 18-65.

Evaluation of angular and positional changes of maxillary third molars following premolar extraction, molar distalization, and non-extraction treatments.

Background: To compare the effects of first premolar extraction, molar distalization, and non-extraction treatments on the angulation and vertical positions of maxillary second molars (MxM2s) and maxillary third molars (MxM3s). To our knowledge, this is the first study to compare the effects of three different treatment types on MxM3 simultaneously.

Methods: Initial (T0) and final (T1) panoramic radiographs of three different patient groups were analyzed: first premolar extraction group (n = 26 patients, 52 MxM2, 52 MxM3), molar distalization group (n = 20 patients, 40 MxM2, 40 MxM3), and non-extraction group (n = 31 patients, 62 MxM2, 62 MxM3).

Sedoanalgesia with dexmedetomidine in daily anesthesia practices: a prospective randomized controlled trial.

Background: Patient safety is important in daily anesthesia practices, and providing deep anesthesia is difficult. Current debates on the optimal anesthetic agents highlight the need for safer alternatives. This study was justified by the need for safer and more effective anesthetic protocols for outpatient hysteroscopic procedures, particularly those conducted outside the operating room.

Comparison of NoSAS score with STOP-Bang and Berlin scores in predicting difficult airway.

Background: This study aimed to compare the effectiveness of the NoSAS, STOP-Bang, and Berlin scoring systems, which are utilized to predict obstructive sleep apnea syndrome (OSAS), in forecasting difficult airway management. Additionally, the study sought to determine which of these scoring systems is the most practical and effective for this purpose.

Methods: Following the ethics committee approval, preoperative NoSAS, STOP-Bang, and Berlin scores were calculated for 420 patients aged 18 years and older who were scheduled for tracheal intubation.

Evaluating the effects of chlorhexidine and vitamin c mouthwash on oral health in non-surgical periodontal therapy: a randomized controlled clinical trial.

Chlorhexidine (CHX) is the most commonly used mouthwash with proven antiplaque and antibacterial activity. The aim is to evaluate the effect of vitamin C (VitC) in CHX mouthwash on plaque accumulation and gingivitis, and to compare it with CHX alone mouthwash and antiseptic phenol-containing mouthwashes. This study conducted as a multicenter, randomized, controlled, double-blind, parallel design clinical study.

Experimental and computational approach on the corrosion inhibition properties of two newly pyrazole derivatives on carbon steel in acid medium.

In the current investigation, the efficiency inhibition of two newly synthesized bi-pyrazole derivatives, namely 2,3-bis[(bis((1 H-pyrazol-1-yl) methyl) amino)] pyridine (Tetra-Pz-Ortho) and 1,4-bis[(bis((1 H-pyrazol-1-yl) methyl) amino)] benzene (Tetra-Pz-Para) for corrosion of carbon steel (C&S) in 1 M HCl medium was evaluated. A Comparative study of inhibitor effect of Tetra-Pz-Ortho and Tetra-Pz-Para was conducted first using weight loss method and EIS (Electrochemical Impedance Spectroscopy) and PDP (Potentiodynamic Polarisation) techniques. Tetra-Pz-Ortho and Tetra-Pz-Para had a maximum inhibition efficacy of 97.