Bioactive Compounds and Antimicrobial Activities in Iranian Ecotypes for Potential Food and Medicinal Uses.

The genus , belonging to the Rosaceae family, exhibits widespread distribution across Iran, comprising 17 species. Hawthorn has garnered significant attention in recent years as a prominent herbal remedy in phytotherapy and culinary applications. Various plant parts, including flowers, leaves, and fruits, have been traditionally employed to address cardiovascular conditions such as hypertension, hypotension, palpitations, and cardiac arrhythmias.

Creation of a Tibia Extension Model With a Perforated Ilizarov Ring System: An Experimental Study in Rats.

Distraction osteogenesis is a valuable clinical technique used to address length discrepancies in long bone deformities. This procedure involves performing an osteotomy at an appropriate site in the bone and correcting the deformity through an extension system. This research aims to investigate the efficacy of a newly developed device for use in rat tibias and to provide an alternative to existing devices used in animal experiments.

Investigation of Consultations Requested by Dermatology Inpatient.

Background: Although dedicated dermatology wards have been closed in some countries, they continue to exist in others. Inpatient consultations requested from dermatologists have been investigated widely. However, those requested by dermatologists have been taken into consideration only in a few studies.

Corrigendum to "LogNNet model as a fast, simple and economical AI instrument in the diagnosis and prognosis of COVID-19" [MethodsX 10 (2023) 102194].

[This corrects the article DOI: 10.1016/j.mex.

The potential of serum elabela levels as a marker of diabetic retinopathy: results from a pilot cross-sectional study.

Background: The aim of this study is to examine the relationship between elabela (ELA), a recently identified peptide also known as Toddler and Apela, and diabetic retinopathy (DR). ELA, produced in various tissues, acts as a natural ligand for the apelin receptor (APJ). Upon reviewing the existing literature, only one study was found investigating ELA, one of the APJ ligands, in the pathogenesis of DR.

The impact of a disaster medicine clinical training program on medical students' disaster literacy.

Background: This study was conducted to assess how students' disaster literacy was affected by the Disaster Medicine Clinical Training Program at the Izmir Democracy University Faculty of Medicine (IDUFM) during the academic year 2022-2023.

Methods: Using an experimental method involving experimental and control groups, measurements were made at different times. The sample consisted of 5th-year students at IDUFM for the experimental group, while the control group was composed of 3rd- and 4th-year students from different buildings with limited interaction with the experimental group.

Correction: Psychometric properties of the Turkish version of modified Freedman questionnaire for sleep quality.

[This corrects the article DOI: 10.1007/s41105-022-00389-2.].

The impact of uric acid levels in the pathophysiology and its contribution to the prediction of diagnosis in restless legs syndrome.

Restless legs syndrome (RLS) is characterized by an uncomfortable urge to move the legs, worsened in the evening, occurring at rest, and relieved temporarily by movement. Although its pathophysiology remains incompletely understood, oxidative stress has been suggested. Uric acid (UA) is a marker associated with oxidative stress, and its reduced levels pose a risk for certain neurodegenerative diseases.

Comparison of Stump Closure Methods in Laparoscopic Appendectomy: Hem-o-Lok Clip and Laparoscopic Titanium Clip.

Background: Appendectomy for acute appendicitis is the most common acute abdominal surgery. Open and laparoscopic appendectomy surgeries are performed with different techniques. Laparoscopic appendectomy has become a widespread method due to its advantages.

Comparison of Cerebral Blood Circulation of Fetuses with Congenital Heart Disease with Healthy Fetuses.

Background: The effect of congenital cardiac malformation on fetal cerebral circulation has not been well known. This study aimed to compare the cerebral blood circulation of fetuses with congenital heart disease (CHD) with healthy fetuses.

Methods: This prospective cohort study included 37 pregnant women who presented to the gynecology and obstetrics department of department of Farabi Hospital, Faculty of Medicine, Karadeniz Technical University for anomaly screening in the second trimester.

Determination of paclobutrazol using square wave voltammetry based on a molecularly imprinted polymer and boron-doped copper oxide/graphene nanocomposite.

In the present study, a novel voltammetric sensor based on a boron-doped copper oxide/graphene (B-CuO-Gr) nanocomposite and molecularly imprinted polymer (MIP) was developed for the detection of paclobutrazol (PAC) in apple and orange juice samples. The B-CuO-Gr nanocomposite was prepared using sol-gel and calcination methods. After modifying glassy carbon electrodes with the B-CuO-Gr nanocomposite, PAC-imprinted electrodes were prepared in the presence of 100.

The effect of music on fistula needle insertion-related pain intensity and pain distress: A single-centre, single-blind, randomised controlled trial.

Background: Patients feel pain and distress when a needle is inserted into the fistula. This affects the comfort of patients. One of the nonpharmacological methods used to decrease pain and stress is music intervention.

Early career psychiatrists' perceptions of and training experience in electroconvulsive therapy: A cross-sectional survey across Europe.

Background: Electroconvulsive therapy (ECT) is a safe and effective treatment for several major psychiatric conditions, including treatment-resistant depression, mania, and schizophrenia; nevertheless, its use remains controversial. Despite its availability in some European countries, ECT is still rarely used in others. This study aims to investigate the experiences and attitudes of early career psychiatrists (ECPs) across Europe towards ECT and to examine how their exposure to ECT influences their perceptions.

Controlled synthesis of ternary acrylamide/sodium acrylate/polyethyleneglycol hybrids by integrating different clays and fillers: a comprehensive evaluation of structural features.

A series of anionic poly(acrylamide--sodium acrylate)/poly(ethylene glycol), PAN/PEG, hybrids were conveniently synthesized free radical aqueous polymerization by integrating bentonite, kaolin, mica, graphene and silica, following a simple and eco-friendly crosslinking methodology. A comparative perspective was presented on how integrated nanofillers affect the physicochemical properties of hybrid gels depending on the differences in their structures. Among the five types of nanofillers, bentonite-integrated hybrid gel had the highest water absorbency, while graphene-integrated gel had the lowest.

Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry.

Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.

Methods: Cross-sectional analysis was conducted in 35 540 patients with HeFH across 50 countries, in the EAS FH Studies Collaboration registry. Prevalence of World Health Organization-defined body mass index categories was investigated in adults (n = 29 265) and children/adolescents (n = 6275); and their association with prevalent ASCVD.

Assessment of Micronutrient Levels in Pediatric Migraine Patients.

Objective: We aimed to evaluate the relationship between attack frequency and severity and serum levels of micronutrient in pediatric migraine patients.

Methods: Children at 2 hospitals from February to December 2022 diagnosed with migraine were reviewed.

Results: A total of 171 patients with a mean age of 14.

The latest in clinical trial results of 5-alpha reductase inhibitors in combination regimens for benign prostatic hyperplasia.

Introduction: BPH/male LUTS is a prevalent condition in the aging male population with multifactorial pathophysiology. Pharmacotherapy remains the cornerstone of treatment in patients who fail conservative treatment. 5-alpha-reductase inhibitors (5-ARIs) is the only class of medication shown to reduce the risk of acute retention and BPH-related surgery and thus, are commonly used along with other 'short acting' medications in combination treatments.

Prognostic Significance of Tumor Budding in Ampullary Carcinomas.

The presence of high tumor budding in colorectal carcinomas is a significant pathological feature indicative of a high potential for lymph node metastasis. Our aim was to investigate the prognostic impact of tumor budding in ampullary carcinomas. We conducted a cohort of 101 consecutive ampullary carcinoma resections to evaluate tumor budding, macroscopic and microscopic subtypes, lymphatic/vascular/perineural invasions, and other histopathological parameters.

Risk Factors in Addition to Short and Long-Term Outcomes With Thin Catheter Surfactant Administration Failure in Preterm Infants: A Retrospective Analysis.

Objective: To evaluate the incidence of thin catheter surfactant administration (TCA) failure and compare short and long-term neonatal outcomes who failed TCA or did not.

Design: Single-center retrospective cohort study. Infants between 25 and 30 weeks of gestational age with respiratory distress syndrome and receiving 200 mg/kg poractant alfa via thin catheter administration were included.

Fertility, pregnancy outcomes, and disease activity during pregnancy in patients with juvenile idiopathic arthritis: a descriptive study.

To investigate the fertility status, pregnancy outcomes, and disease activity during and after pregnancy in patients with juvenile idiopathic arthritis (JIA) currently being followed up at an adult rheumatology clinic. This study included 141 adult patients diagnosed with according to the International League of Associations for Rheumatology criteria, who are now monitored at an adult rheumatology clinic. Data on demographics, disease characteristics, medication history, fertility status, and pregnancy outcomes were collected through medical records and patient interviews.

Maximizing phonation: impact of inspiratory muscle strengthening on vocal durations and pitch range.

Background: This study investigated the acute effects of inspiratory muscle warm-up (IWU) on vocal performance in singers. Proper vocal and respiratory warm-up can enhance vocal range, quality, and endurance. The aim was to determine whether IWU improves maximum phonation time and pitch range, contributing to better voice production efficiency (vocal efficiency) and reduced fatigue.

Evaluation of the relationship between nutrition literacy, Mediterranean diet compliance, ecological footprint and sustainable environmental attitudes in adolescents.

Objective: This study aimed to evaluate the relationship between nutrition literacy, Mediterranean diet compliance, ecological footprint and sustainable environmental attitudes in adolescents.

Methods: This descriptive and cross-sectional study was conducted with 673 adolescents aged 14-18 years. The individuals' general characteristics were questioned.