Assessment of the content and quality of YouTube videos on retinopathy of prematurity: a cross-sectional study.

Purpose: This study aimed to evaluate the quality and reliability of YouTube videos as an educational resource about retinopathy of prematurity.

Methods: Videos were sourced from YouTube using the search terms "retinopathy of prematurity" and "premature retinopathy" with the default settings. Each video was assessed on the following metrics: views, likes, dislikes, comments, upload source, country of origin, view ratio, like ratio, and video power index.

Experiences of Nurse Managers in the 2023 Kahramanmaras, Turkey Earthquakes: A Qualitative Study.

Background: Nurse managers play a critical role in disaster response and management; yet research on their experiences in earthquakes remains limited.

Objective: This study aimed to explore the experiences of nurse managers in the Kahramanmaras, Turkey, earthquakes.

Methods: A phenomenological approach was used to guide this study, exploring the lived experiences of nurse managers who worked during the 2023 earthquakes in Kahramanmaras, Turkey.

Assessing the sustainable development in the European Union: influence of municipal waste, industrial waste, and waste related patents.

Waste has emerged as a pressing concern for the environment, primarily stemming from the processes of urbanization and industrialization. The substantial volumes of waste generated pose a serious threat to the environment, as they spread out harmful substances in the soil and release methane emissions into the atmosphere. To effectively address this issue, this study explores the impact of municipal and industrial waste, as well as waste-related innovation on the load capacity factor (LCF) from 2005 to 2020.

Antibiotic-derived approaches in cancer therapy: effectiveness of ikarugamycin in hexokinase-2 inhibition, tissue factor modulation, and metabolic regulation in breast cancer.

We aimed to explore the role of ikarugamycin (IKA) in breast cancer, its connection with hexokinase-2 (HK-2) repression, and tissue factor (TF). This study sought to extend the role of HK-2 as a TF activator in a comprehensive analysis of these interactions from the enzyme, gene, and protein levels. The investigation was performed with MDA-MB-231 and MCF-7 breast cancer lines.

Precise Measurement of the e^{+}e^{-}→D_{s}^{+}D_{s}^{-} Cross Section at Center-of-Mass Energies from Threshold to 4.95 GeV.

Using the e^{+}e^{-} collision data collected with the BESIII detector operating at the BEPCII collider, at center-of-mass energies from the threshold to 4.95 GeV, we present precise measurements of the cross section for the process e^{+}e^{-}→D_{s}^{+}D_{s}^{-} using a single-tag method. The resulting cross section line shape exhibits several new structures, thereby offering an input for a future coupled-channel analysis and model tests, which are critical to understand vector charmonium-like states with masses between 4 and 5 GeV.

Protective effect of dapagliflozin on lipopolysaccharide-induced acute lung injury via the SIRT-1/PGC-1α pathway.

Background: Acute systemic inflammation affects many organs and it occurs in a wide range of conditions such as acute lung injury (ALI). Inflammation-triggered oxidative pathways together with the caspase activation seen in ALI, result in apoptosis. Dapagliflozin (DPG) is an agent that is known to have oxidative stress-reducing and anti-inflammatory effects in many tissues.

Distinct TYRO3 and PROS1 expression levels contribute to preeclampsia pathogenesis.

Preeclampsia (PE) is a severe placental complication occurring after the 20th week of pregnancy. PE is associated with inflammation and an increased immune reaction against the fetus. TYRO3 and PROS1 suppress inflammation by clearing apoptotic cells.

Revolutionising Osseous Biopsy: The Impact of Artificial Intelligence in the Era of Personalised Medicine.

In a rapidly evolving healthcare environment, artificial intelligence (AI) is transforming diagnostic techniques and personalised medicine. This is also seen in osseous biopsies. AI applications in radiomics, histopathology, predictive modelling, biopsy navigation, and interdisciplinary communication are reshaping how bone biopsies are conducted and interpreted.

Effects of Tasimelteon Treatment on Traumatic Brain Injury Through NRF-2/HO-1 and RIPK1/RIPK3/MLKL Pathways in Rats.

Secondary brain damageafter traumatic brain injury (TBI) involves oxidative stress, neuroinflammation, apoptosis, and necroptosis and can be reversed by understanding these molecular pathways. The objective of this study was to examine the impact of tasimelteon (Tasi) administration on brain injury through the nuclear factor erythroid 2-related factor 2 (NRF-2)/heme oxygenase-1 (HO-1) and receptor-interacting protein kinase 1 (RIPK1)/receptor-interacting protein kinase 3 (RIPK3)/mixed lineage kinase domain-like (MLKL) pathways in rats with TBI. Thirty-two male Wistar albino rats weighing 300-350 g were randomly divided into four groups: the control group, trauma group, Tasi-1 group (trauma + 1 mg/kg Tasi intraperitoneally), and Tasi-10 group (trauma + 10 mg/kg Tasi intraperitoneally).

Fluvoxamine may reverse the decrease in filtering capacity that occurs in acute kidney injury by increasing IL-10 and ACE expressions and preserving AQ-2, AQ-4, CL-5, and ZO-1 expressions.

The kidneys have a regulatory role in many diseases with their diuresis function and capacity to maintain electrolyte balance. In case of extensive damage, the kidney's filtration capacity is impaired and cannot fulfill its functions. Fluvoxamine (FLV), an antidepressant agent, has antioxidant and anti-inflammatory effects.

Direct Neck Skin Excision for Correction of Aging Signs Confined to Skin Laxity and Sagging Skin in the Neck: A Local Anesthesia-Based Day Surgery Optimal for Younger Women.

Background: The removal of excessive neck skin is considered the key parameter in the best postoperative outcome after a neck rejuvenation surgery.

Objective: To evaluate the utility of a local anesthesia-based direct neck skin excision surgery in patients with skin laxity and sagging skin in the neck in terms of postoperative aesthetic outcome and patient satisfaction within a 12-month follow-up period.

Materials And Methods: A total of 47 female patients who underwent local anesthesia-based direct neck skin excision surgery for the rejuvenation of skin laxity and sagging skin in the cervical neck were included.

The monocyte-to-HDL-cholesterol ratio predicts new-onset atrial fibrillation in patients with acute STEMI.

Objective: Newly diagnosed AF (NOAF) associated with acute STEMI holds significant relevance in clinical practice. This study seeks to assess the role of the monocyte to HDL-C ratio (MHR) in predicting NOAF in these patients.

Methods: Between July 2017 and May 2018, 663 patients who underwent primary PCI for STEMI were retrospectively analyzed.

Comparison of the incidence of recovery agitation with two different doses of ketamine in procedural sedation: A randomized clinical trial.

Objectives: The objective was to compare the incidence of recovery agitation and efficacy of two different intravenous (IV) doses of ketamine (0.5 mg/kg vs. 1 mg/kg) in adult patients who presented to the emergency department (ED) requiring procedural sedation with ketamine.

Effect of UV Light Exposure Duration on the Removal of Exfoliation Agent Residues in Two-Dimensional Perovskite Nanosheets: An AFM Study.

Accurate determination of dielectric properties and surface characteristics of two-dimensional (2D) perovskite nanosheets, produced by chemical exfoliation of layered perovskites, is often hindered by exfoliation agent residues such as tetrabutylammonium (TBA). This study investigates the effect of ultraviolet (UV) light exposure duration on the removal of TBA residues from 2D Ca2NaNb4O13- nanosheets deposited on silicon substrates via Langmuir-Blodgett method using atomic force microscopy (AFM). Nanoscale adhesion forces between silicon AFM tips and nanofilms exposed to UV light for 3, 12, 18, and 24 hours were measured.

Developing and Implementing an Integrated Family Education Program (IPMD-F) for Parents of Children With Reading Difficulties: Insights From an Action Research Study.

Purpose: This research aims to identify the problems and needs of families of children with reading difficulties, develop an Integrated Process-Based Family Education Program (IPMD-F) to address these needs, and implement it.

Methods: The study used a community-based participatory action research approach, following a four-stage process: general information collection, needs identification and action plan creation, development and implementation of the IPMD-F, and evaluation. Conducted during the 2023-2024 academic year in Ankara, Turkey, with 16 volunteer parents of children diagnosed with learning disabilities, data were collected using qualitative and quantitative tools.

Risk factors for the involvement of sentinel lymph nodes in endometrial cancer (TRSGO-SLN-010).

Objective: This research was undertaken to identify risk factors for the involvement of sentinel lymph nodes (SLNs) in cases of endometrial cancer.

Methods: From February 2016 to April 2021, the cases of 874 women with endometrial cancer treated with the SLN algorithm at 11 institutions were analyzed in this retrospective study. Clinical and pathologic data were reviewed, and logistic regression was applied to identify predictive factors for SLN involvement.

Vulvar inspection at the time of cervical cancer screening: European Society of Gynaecological Oncology (ESGO), International Society for the Study of Vulvovaginal Disease (ISSVD), European College for the Study of Vulval Disease (ECSVD), and European Federation for Colposcopy (EFC) consensus statements.

Background: Vulvar squamous cell carcinoma incidence is increasing, especially among women under 60, largely attributed to human papillomavirus infections. Precursor pre-invasive vulvar lesions are frequently underdiagnosed. Routine vulvar inspection during cervical cancer screening could offer an opportunity for the detection of these lesions.

Predictive ability of systemic coagulation-inflammation index on early fistula failure after radiocephalic arteriovenous fistula creation.

Introduction: To the best of our knowledge, a possible predictive relationship between the systemic coagulation-inflammation index (SCI) and arteriovenous fistula (AVF) failure following AVF creation has not yet been examined. We therefore designed this study to examine the predictive ability of SCI on postoperative early AVF failure in patients undergoing primary radiocephalic AVF operation.

Methods: A total of 189 patients who underwent primary radiocephalic AVF operation for hemodialysis access were included in this retrospective observational cohort study, and then divided into two groups according to whether AVF failure occurred within the first 3 months after the operation; as failed AVF group ( = 44) and non-failed AVF group ( = 145).

[An Endemic Disease in the Black Sea Region: Leptospirosis].

Leptospiroz, insan ve hayvanları etkileyen, Antarktika hariç tüm kıtalarda bulunan ve Leptospira cinsi spiroketlerin neden olduğu zoonotik bir enfeksiyon hastalığıdır. Salgınlara yol açabilmesi nedeniyle halk sağlığı açısından önemli bir hastalıktır. Bu çalışmada; kliniğimizde leptospiroz tanısıyla izlenen 11 olgunun, epidemiyolojik özellikleri, saptanan etkenler, klinik ve laboratuvar bulguları açısından retrospektif olarak değerlendirilmesi amaçlanmıştır.

A protocol for the investigation of the intramolecular vibrational energy redistribution problem: the isomerization of nitrous acid as a case of study.

The conformational isomerization of nitrous acid (HONO) promoted by excitation of the or stretching normal coordinates is the first observed case of an infrared-induced photochemical reaction. The energy captured by the excited normal modes is redistributed into a highly excited vibrational level of the torsion normal coordinate, which is the isomerization reaction coordinate. Herein, we present simple numerical methods to qualitatively investigate the coupling between the normal coordinates and the possible gateways for vibrational energy redistribution leading to the isomerization process.

Optimizing Granulocyte-Colony Stimulating Factor Dosing Scheme in Healthy Stem Cell Donors for Allogenic Transplantation: A Retrospective Cohort Study of Single Dose vs. Split Dose.

Objectives The optimal dosing schedule strategy for granulocyte colony-stimulating factor (G-CSF) in healthy stem cell donors remains controversial. This study aimed to compare the efficacy of once-daily versus twice-daily G-CSF administration in allogeneic stem cell donors. Materials and methods We retrospectively analyzed data from 388 healthy unrelated donors (282 males, 106 females) who underwent stem cell mobilization at our center between September 2018 and June 2022.

Analyzing the Effectiveness of Different Delivery Methods for Remineralization Agents in Pediatric Dental Health: A Systematic Review.

Pediatric dental health is critically impacted by enamel demineralization and early-stage caries, with remineralization therapies playing a vital role in preventing progression. This systematic review evaluates the effectiveness of various delivery methods for remineralization agents in pediatric patients aged 3-15 years, focusing on varnishes, gels, foams, and sprays. Studies were included if they were randomized controlled trials (RCTs), cohort studies, or case-control studies involving pediatric patients with early-stage caries or enamel demineralization, while studies with non-pediatric populations, unrelated treatments, or significant methodological flaws were excluded.