372,989 results match your criteria: "Turkey; **Koc University Research Center for Translational Medicine KUTTAM[Affiliation]"

Sleeve gastrectomy with antral resection provides more effective weight loss in patients with super obesity.

Langenbecks Arch Surg

January 2025

Faculty of Medicine Training and Research Hospital, Department of Gastrointestinal Surgery, Sakarya University, Sakarya, Turkey.

Background: Obesity is a growing health issue that contributes to numerous diseases and lowers quality of life. In patients with super obesity (BMI > 50 kg/m²), bariatric surgery, particularly laparoscopic sleeve gastrectomy (LSG), is a common treatment option. However, the role of antral resection (AR) in LSG remains unclear, especially in this high-risk population.

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Purpose: The choice of the best management for Adult Spine Deformity (ASD) is challenging. Health-related quality of life (HRQoL), comorbidities, symptoms and spine geometry, along with surgical risk and potential residual disability play a role, and a definite algorithm for patient management is lacking. Machine learning allows to analyse complex settings more efficiently than other available statistical tools.

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Background: To compare the characteristics of type 1 macular neovascularization (MNV) and the surrounding choriocapillaris (CC) perfusion in patients with neovascular age-related macular degeneration (nAMD) versus those with pachychoroid neovasculopathy (PNV) using swept-source optical coherence tomography angiography (SS-OCTA).

Methods: This retrospective study included 64 treatment-naïve eyes (37 nAMD, 27 PNV) with type 1 MNV. SS-OCTA images were analysed to measure MNV area and perimeter, and CC flow deficits (FD) in five concentric rings surrounding the lesion.

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Copris are part of the Scarabaeidae family of Coleoptera. Copris are dung beetles or coprophagous beetles. These insects are called tunnelers because they excavate channels in the substrate.

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Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.

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The cranium from the Octagon in Ephesos.

Sci Rep

January 2025

Department of Evolutionary Anthropology, University of Vienna, Djerassiplatz 1, A-1030, Vienna, Austria.

During excavations in 1929, a well-preserved skeleton was discovered in a sarcophagus in the Octagon at Ephesos (Turkey). For the following century, archaeologists have speculated about the identity of this obviously notable person. Repeated claim is that the remains could represent Arsinoë IV, daughter of Ptolemy XII, and younger (half-)sister of Cleopatra VII.

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The International System for Serous Fluid Cytopathology (TIS) survey in preparation for TIS 2.0.

J Am Soc Cytopathol

December 2024

Department of Cellular Pathology, Guy's & St. Thomas' NHS Foundation Trust, London, UK.

Introduction: The International System for Serous Fluid Cytopathology (TIS) has gained acceptance and has led to literature validating original concepts and suggesting refinements. In preparation for the second edition of TIS, editors generated a survey to solicit experience with and opinions about TIS.

Materials And Methods: An online survey available from March 8 to June 15, 2024, included 56 questions, offered in 7 languages, related to the practice of serous fluid cytopathology.

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Background: Psoriasis is a chronic inflammatory skin disease with a genetic predisposition and autoimmune component, often treated with immunomodulators such as biologic therapies.

Objectives: In this study, the authors evaluated the effectiveness and safety of two of these over a 52-week treatment period.

Methods: A double-center retrospective cohort study was conducted, enrolling patients with moderate to severe psoriasis who received either guselkumab or risankizumab at dermatology clinics for a minimum of 52-weeks.

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Invisible danger: The secondary effects of disasters.

Am J Emerg Med

January 2025

Hacettepe University, Faculty of Medicine, Department of Emergency Medicine, 06120 Altindag Ankara, Turkey. Electronic address:

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Background And Objective: Evidence regarding perioperative results and long-term functional outcomes of robotic-assisted kidney transplantation (RAKT) is limited. We evaluated perioperative surgical results and long-term functional outcomes of RAKT in patients receiving kidney transplants from living donors.

Methods: This retrospective analysis is based on a prospective multicenter cohort study conducted from July 2015 to October 2023 across ten European centers.

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Background: Segmentectomy operation became a preferable operation for small lesions due to the importance of saving lung parenchyma. Using robotic technology has too many advantages for segmentectomy operations. Websites such as YouTube have become educational tools for surgical trainees.

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Three-dimensional (3D) printing is a rapidly evolving technology. This study focuses on developing biopolymeric inks tailored for Three-dimensional (3D) printing applications, specifically to produce 3D-printed materials for wound dressing. Humic Acid (HA) was incorporated into the ink formulations due to its anti-inflammatory properties.

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Flow-Electrode capacitive deionization for enhanced selective separation of Ammonia, Phosphorus, and caproate from sewage sludge fermentation: Performance and mechanistic insights.

Bioresour Technol

January 2025

School of Environment and Ecology, Jiangnan University, Wuxi 214122 China; Jiangsu Collaborative Innovation Center of Water Treatment Technology and Material, Suzhou University of Science and Technology, Suzhou 215011 China. Electronic address:

Caproic acid has broad applications and can be produced from activated sludge via fermentation, but its quality is hindered by ammonia (NH-N) and reactive phosphorus (RP) in the fermentation broth. However, flow-electrode capacitive deionization (FCDI), a novel ion separation technology that operates continuously without secondary pollution seems to be an efficient process that separates the ions. The results showed that at pH 5.

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Coumarin compounds have heterocyclic core with different properties such as high quantum yields, broad Stokes shifts, and superior photophysical and biological activity. It is known that fluorescence properties increase with increased intramolecular charge transfer in systems where electron-withdrawing or donor groups are attached to different positions of the coumarin compound. When these compounds interact with analytes in the environment, the analytes in the environment can be detected by quenching or increasing fluorescence.

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A series of novel phenyl naphthalene-2-sulfonate-based thiosemicarbazones (5a-v) were synthesized and evaluated for their inhibitory activity against human carbonic anhydrases I and II (hCA I and hCA II). Compounds 5d and 5p demonstrated the highest inhibitory potency, with IC values of 4.32 ± 0.

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Thread-Filler: A Standardized Combination Therapy.

J Craniofac Surg

January 2025

Department of Plastic, Reconstructive, and Aesthetic Surgery, Bilkay Clinic, Izmir, Turkey.

Advanced technology and increasing knowledge about aging faces have combined to create the illusion of thread lifting to replace surgical interventions. However, results that came far beyond expectations led to a heavy suspicion of these tools. However, combined treatments with fillers would have better outcomes with a synergetic effect.

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Introduction: Somalia is continuing to recover from three decades of underdevelopment, political instability, civil unrest, and protracted humanitarian crises. However, Somalia has one of the lowest maternal health indicators in the world. For instance, the maternal mortality ratio is 621 per 100,000 live births.

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Childhood cancers, with leukemia at the forefront, comprise 97% acute leukemia and 3% chronic leukemia, with 75% of acute leukemias being of lymphoblastic origin. Over the past 50 years, survival rates have witnessed a remarkable increase, progressing from around 10% to achieving cure rates exceeding 90% in certain childhood ALL subgroups with the advent of combined therapies. Between 1999 and 2018, a total of 123 patients diagnosed with B-ALL were initially identified, but after applying exclusion criteria, 105 patients were included in the evaluation, who were treated with COG protocols at our center.

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Background: There is an increased prevalence of mental health problems in various population groups as a result of the COVID-19 pandemic and its consequences, especially regarding anxiety, stress, depression, fear, and sleep disturbances, require to be investigated longitudinally.

Objective: This study aimed to determine the impact that the COVID-19 pandemic had on the mental health of Nursing students, as well as to examine other associated factors such as anxiety, fear, sleep disturbances, and coping strategies.

Method: This systematic review and meta-analysis were designed following the PRISMA guidelines and were registered in PROSPERO with code CRD42024541904.

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Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.

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What Do Hip and Knee Arthroplasty Surgeons Agree on? Moving Forward Collectively.

J Am Acad Orthop Surg Glob Res Rev

November 2024

From the Acibadem University, Istanbul, Turkey (Dr. Parvizi and Dr. Tuncay); the Sinai Hospital, Baltimore, MD (Dr. Mont); the McMaster University, Hamilton, Ontario, Canada (Dr. Bhandari); the Vall d'Hebron University Hospital, Barcelona, Spain (Dr. Guerra-Farfan); and the Hospital for Special Surgery, New York, NY (Dr. Lee).

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Genetic Variability of Pestivirus A (BVDV-1) Circulating in Cattle From Eastern Turkey.

Vet Med Sci

January 2025

Department of Virology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van, Turkey.

Background: Bovine viral diarrhoea virus (BVDV) infection, caused by Pestiviruses A and B, with various clinical findings and causes significant economic losses. This disease is common in Turkey as well as in other countries, especially in European countries.

Objective: This study was designed to determine the genotypes of BVDVs and their variability among cattle in eastern Turkey.

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Objectives: Our aim was to evaluate the comparative effects of sertraline and vortioxetine against stress-induced brain injury in rats.

Methods: The rats were assigned to a nonstress group (NSG), stress-treated control (StC), sertraline + stress (SSt), and vortioxetine + stress (VSt) groups. Sertraline and vortioxetine (10 mg/kg) were given orally by gavage to the SSt and VSt groups.

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