[Anatomical and functional outcomes of the "3+PRN" therapeutic protocol in the treatment of diabetic macular edema].

Purpose: To evaluate the anatomical and functional results of the "3+PRN" protocol in the treatment of diabetic macular edema (DME), determine the predictive factors for good final visual acuity, and compare it to other protocols.

Materials And Methods: We conducted a retrospective, descriptive, comparative, cross-sectional study of patients with DME, which we dubbed HTSM. All patients were treated with three monthly initial intravitreal injections (IVT) of 1.

Cystic echinococcosis (Echinococcus granulosus sensu lato infection) in Tunisia, a One Health perspective for a future control programme.

The emergence of pandemics with dramatic consequences for human health has obscured endemic diseases that continue to pose a problem for human and animal health in several regions of the world. Among these diseases, cystic echinococcosis, a zoonotic parasitic infection caused by a group of cestodes, Echinococcus granulosus sensu lato, remains a real human and animal health problem in several regions of the world, including the Mediterranean Basin. Despite the implementation of a number of governmental control programmes using several tools (dog treatment, meat inspection, etc.

[Zoonotic potential of brucellosis in marine mammals].

Introduction: Brucellosis in marine mammals (cetacean and pinnipeds) has emerged in a very significant way during the last two decades. Currently and are the two recognized species in marine mammals, but available information is still limited. Several genotypes have been identified, and studies on the relationship between sequence type (ST) and organ pathogenicity or tropism have indicated differences in pathogenesis between sequences in cetaceans.

Air embolism complicating endoscopic retrograde cholangiopancreatography.

Venous air embolism is a rare but potentially life threatening complication of endoscopic retrograde cholangiopancreatography. Diagnosis is difficult because of the lack of specific signs or symptoms. A 62-year-old man underwent endoscopic retrograde cholangiopancreatography for choledocholithiasis.

Impact of an educational intervention on patient safety culture among gynecology-obstetrics' healthcare professionals.

Background: In recent years, patient safety has begun to receive particular attention and has become a priority all over the world. Patient Safety Culture (PSC) is widely recognized as a key tenet that must be improved in order to enhance patient safety and prevent adverse events. However, in gynecology and obstetrics, despite the criticality of the environment, few studies have focused on improving PSC in these units.

Primary α-Phosphino- and α-Arseno-Nitriles, Analogues of α-Aminonitriles.

More than 170 years after the synthesis of α-aminonitriles by the reaction of Strecker, α-phosphinonitriles, and α-arsenonitriles have been prepared and characterized by NMR and IR spectroscopy. For the simplest derivatives, the reaction was carried out by reaction of cyanomethyltributylstannane with phosphorus or arsenic trichloride, followed by a chemoselective reduction of the dichlorophosphine and dichloroarsine formed to the corresponding primary phosphine and arsine. The phosphinoacetonitrile can be stored at -80 °C for months in its pure state, but arsenoacetonitrile decomposes at this temperature.

Knowledge, attitudes and practices of sheep owners regarding abortion in Northern Tunisia.

Background: Abortion in ewes causes high economic losses and represents a threat for human health due to abortive zoonotic pathogens.

Objective: The present study aimed to assess the knowledge, attitudes and practices (KAP) among sheep owners in the northern Tunisia regarding ewes' abortions.

Methods: Between February 2021 and May 2022, a structured questionnaire containing both close and open-ended questions was applied to 120 sheep owners in northern Tunisia.

Linking farmers' perceptions and management decision toward sustainable agroecological transition: evidence from rural Tunisia.

Global food systems face sustainability challenges like undernourishment, inequity, resource degradation, and pollution. Food production and consumption drive environmental change with greenhouse gas emissions, biodiversity loss, and land-system shifts. The climate change crisis has intensified concerns about the ecological impact of these systems.

[Not Available].

Objectives: Our aims were to assess cognitive impairment in bipolar patients in remission compared with healthy controls, and to study its connection to clinical and therapeutic factors.

Methodology: This was a case-control study of patients with bipolar disorder (BD) in remission and matched healthy controls. It was carried out at the Hédi Chaker University Hospital in Sfax, Tunisia.

Exposure of wetlands important for nonbreeding waterbirds to sea-level rise in the Mediterranean.

Sea-level rise (SLR) is expected to cause major changes to coastal wetlands, which are among the world's most vulnerable ecosystems and are critical for nonbreeding waterbirds. Because strategies for adaptation to SLR, such as nature-based solutions and designation of protected areas, can locally reduce the negative effects of coastal flooding under SLR on coastal wetlands, it is crucial to prioritize adaptation efforts, especially for wetlands of international importance for biodiversity. We assessed the exposure of coastal wetlands important for nonbreeding waterbirds to projected SLR along the Mediterranean coasts of 8 countries by modeling future coastal flooding under 7 scenarios of SLR by 2100 (from 44- to 161-cm rise) with a static inundation approach.

New Born Screening of Hemoglobinopathies in a Center Tunisian Population.

Sickle cell diseases, β-thalassemia, and other hemoglobinopathies are common in Africa. Their distribution differs from one region to another. There are higher frequencies in Western and Northern Africa.

[Retrospective study of 60 cases of uterine rupture at the Maternity Center of Monastir, Tunisia].

Uterine rupture is a life-threatening obstetric complication. The purpose of this study was to investigate the epidemiological features, maternal and foetal prognosis and different treatment options for uterine rupture in healthy and scarred uteri. We conducted a retrospective monocentric descriptive and analytical study of 60 cases of uterine rupture collected in the Department of Gynaecology-Obstetrics of the Center of Maternity and Neonatology, Monastir, from 2017 to 2021.

[Prevalence and predictors of post-traumatic stress disorder in road traffic accidents].

Introduction: trauma-related disorders following a road accident have both a health and an economic impact.

Methods: we conducted a prospective study to determine the prevalence of these disorders, and to identify risk factors in subjects victims of road accidents and hospitalized in the Department of Orthopedic Surgery and Traumatology of the University Hospital Center of Sfax-Tunisia.

Results: a total of sixty-ten subjects were included in this study.

A pareto strategy based on multi-objective optimal integration of distributed generation and compensation devices regarding weather and load fluctuations.

In this study, we present a comprehensive optimization framework employing the Multi-Objective Multi-Verse Optimization (MOMVO) algorithm for the optimal integration of Distributed Generations (DGs) and Capacitor Banks (CBs) into electrical distribution networks. Designed with the dual objectives of minimizing energy losses and voltage deviations, this framework significantly enhances the operational efficiency and reliability of the network. Rigorous simulations on the standard IEEE 33-bus and IEEE 69-bus test systems underscore the effectiveness of the MOMVO algorithm, demonstrating up to a 47% reduction in energy losses and up to a 55% improvement in voltage stability.

[Procalcitonin: The Ideal Biomarker To Guide Initiation, Change and Withdrawal of Antibiotics in Septic Burn Patients?].

The goal of this study was to assess plasma procalcitonin (PCT) concentrations during infectious events of burns in the ICU. We conducted a prospective, observational study in a 20-bed Burn Intensive Care Unit in Tunisia. A total of 120 septic patients admitted to the Burn ICU were included in our study.

[Burns and Diabetes Mellitus: Epidemiology, Clinical Presentation and Prognosis].

Burns in diabetics are quite frequent and serious in relation to diabetic neuropathy, which is common in this population, delaying healing and predisposing to the risk of infection. The objective of this study was to describe the characteristics of burns in diabetics hospitalized at the CTB of Tunis over 18 months. During the study period, 891 patients were hospitalized, including 43 diabetics (5%).

Benefit of intrapleural fibrinolytic therapy in the treatment of complicated parapneumonic effusion and empyema.

Our study aimed to assess the benefit of intrapleural fibrinolysis before resorting to surgery to treat complicated parapneumonic effusion and empyema. We conducted a retrospective and descriptive study, including all patients hospitalized in the intensive care unit (ICU) of the Abderhaman Mami hospital, Tunisia for empyema treated with instillation of intrapleural fibrinolytic therapy between the 1 January 2000 and 31 December 2016. In all patients, empyema was diagnosed on clinical features, imaging findings (chest X-ray, thoracic echography and/or computed tomography (CT), and microbiological data.

Camel-Derived Nanobodies as Potent Inhibitors of New Delhi Metallo-β-Lactamase-1 Enzyme.

The injudicious usage of antibiotics during infections caused by Gram-negative bacteria leads to the emergence of β-lactamases. Among them, the NDM-1 enzyme poses a serious threat to human health. Developing new antibiotics or inhibiting β-lactamases might become essential to reduce and prevent bacterial infections.

Major mistakes in scientific medical writing based on manuscripts' reviews.

Introduction: Peer review is a crucial process in ensuring the quality and accuracy of scientific research. It allows experts in the field to assess manuscripts submitted for publication and provide feedback to authors to improve their work.

Aim: To describe mistakes encountered while peer reviewing scientific manuscripts submitted to "La Tunisie Médicale" journal.

Weight excess among high-school students: Relation with mental health and sociodemographic factors.

Introduction: The escalating prevalence of adolescent obesity represents a complex public health challenge, influenced by interactions of environmental, socio-economic, and behavioral factors. Recent studies reveal a surge in addictive substance use among adolescents, with non-substance addictions. Overweight adolescents are particularly susceptible to risky behaviors.