905 results match your criteria: "Tunis El Manar University[Affiliation]"

Retroperitoneal leiomyosarcoma diagnosis and management in a chronic kidney disease context: A case report.

Int J Surg Case Rep

November 2024

Department of Surgery A La Rabta Hospital, Tunis, Tunisia; Faculty of medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Introduction And Importance: While the treatment approach for sarcomas seems straightforward and well-defined, we often encounter several diagnostic or therapeutic challenges in clinical practice. This article presents a case of retroperitoneal leiomyosarcoma in a patient with chronic kidney disease, highlighting the complexity of managing such cases.

Case Report: A 63-year-old woman with a history of chronic kidney disease presented with a progressively enlarging mass in her right flank.

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Introduction: Patient education is crucial in managing chronic diseases like Juvenile Idiopathic Arthritis (JIA). Traditional methods such as videos and brochures often fail to maintain long-term knowledge retention. Therapeutic Patient Education (TPE) offers a more effective, patient-centered approach.

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: Poor medication adherence results in negative health outcomes and increased healthcare costs. Several healthcare professionals provide interventions to improve medication adherence, with the effectiveness of nurse-led interventions in people with chronic diseases remaining unclear. : This study sought to evaluate the effectiveness of nurse-led interventions for improving medication adherence in adults with chronic conditions.

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In this letter, we commented on the article by Wu . We examined the interactions between mesenteric adipose tissue, creeping fat, and gut microbiota in Crohn's disease (CD), a condition marked by chronic gastrointestinal inflammation with a rising global incidence. The pathogenesis of CD involves complex genetic, environmental, and microbial factors.

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Oxybutynin induced blindness in a child: Case report.

Therapie

November 2024

Department of Collection and Analysis of Adverse Effects, 1006 Tunis, Tunisia; Research Unit: UR17ES12, 1006 Tunis, Tunisia.

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Cytomegalovirus reactivation (CMV-R) is a frequent complication post-allogeneic hematopoietic stem cell transplantation (allo-HSCT), associated with poor outcomes. Previous studies have demonstrated the protective effect of CMV-R against relapse after allo-HSCT for acute myeloblastic leukemia (AML). However, this impact remains unclear in acute lymphoblastic leukemia (ALL).

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Psychometric properties of the Arabic Stress Numerical Rating Scale (SNRS-11) in adolescents.

Sci Rep

December 2024

The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry "Ibn Omrane", Razi Hospital, 2010, Manouba, Tunisia.

Article Synopsis
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Background: Although the positive association between impairments in metacognitive capacity and negative symptoms in people with schizophrenia spectrum disorders is widely evidenced in the literature, the explaining mechanisms of this association are still less known and poorly understood. This study aims to bridge this knowledge gap by testing the hypothesis that COMT rs4680 variants will act as moderators in the relationship between certain metacognitive domains and negative symptoms' severity.

Method: A cross-sectional study was carried-out during the period between February and March 2024.

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[Not Available].

Tunis Med

November 2024

Research Unit UR18ES01 'Obesity: aetiopathogeny, pathophysiology and treatment', Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Introduction: Childhood obesity, a true international epidemic, is a multifactorial pathology including genetic and environmental factors.

Aim: Determine the prevalence and risk factors of overweight in Tunisian schoolchildren in the Bardo region, an urban department of the Tunis governorate.

Methods: Descriptive and cross-sectional study involving schoolchildren aged between 10 and 12 years old.

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Background: Due to the elevated global prevalence of its consumption, and the detrimental health effects it can have, caffeine use disorder (CUD) should receive a great deal of attention from clinicians and the research community in Arab countries as an area of concern. To help advance the field, this study aimed to translate the Caffeine Use Disorder Questionnaire (CUDQ) into the Arabic language, and examine its psychometric properties in community adults.

Methods: A descriptive, observational and cross-sectional study was carried out during the period from May to July 2024.

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Background: Research on anxiety in patients with schizophrenia of Arab origin is surprisingly scarce, particularly given that expressions of both psychotic disorders and anxiety disorders can be largely shaped by cultural factors. This study proposes to complement previous research by exploring the psychometric characteristics of an Arabic translation of the Staden Schizophrenia Anxiety Rating Scale (S-SARS) in chronic, remitted patients diagnosed with schizophrenia. As the Arabic version of the Generalized Anxiety Disorder 7-Item Scale (GAD-7) has not been previously validated in Arabic in patients with schizophrenia, this study had as a secondary aim to investigate the psychometric properties of this scale before its use.

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Vitamin D association with systemic sclerosis and its clinical features: A systematic review, meta-analysis, and meta-regression.

J Scleroderma Relat Disord

October 2024

Research Laboratory in Immunology of Renal Transplantation and Immunopathology (LR03SP01), Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.

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Anorectal melanoma: A case report of an unusual localization.

Int J Surg Case Rep

December 2024

Department of Surgery A La Rabta Hospital, Tunis, Tunisia; Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Introduction And Importance: Primary anorectal melanoma (ARM) is a rare neoplasm with an extremely poor prognosis. It represents less than 1 % of all melanomas and accounts for less than 1 % of anorectal malignancies. We report a case of anorectal primary melanoma treated surgically.

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Introduction And Importance: Transomental hernia (TOH) is an extremely rare clinical condition that represents 1-4% of all internal hernias. Spontaneous TOH occurs in patients with no history of surgery or previous abdominal trauma. It happens after protrusion of the abdominal viscera, commonly the small bowel loops through a defect on the great omentum.

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Hook-shaped distal common bile duct due to peptic ulcer mimicking cholangiocarcinoma.

Int J Surg Case Rep

December 2024

Department of Surgery A La Rabta Hospital, Tunis, Tunisia; Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Introduction And Importance: Internal and spontaneous bilio-digestive fistulas, without primary biliary disease, are an infrequent complication of the upper digestive tract. We report a case of a Hook-shaped distal common bile duct due to peptic ulcer mimicking cholangiocarcinoma.

Case Report: A 63-year-old patient, with no medical history, presented to the emergency department with recent jaundice.

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Background: Preoperative biliary drainage (PBD) has been introduced to control the negative effects of obstructive jaundice in patients undergoing pancreaticoduodenectomy (PD). The optimal time interval between PBD and PD remains unclear. The purpose of our systematic review and meta-analysis was to evaluate the optimal period for PBD before PD.

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To establish a radiological national reference for agricultural soil across Tunisian oases and assess the risk to human health associated with date consumption, with a focus on comparing the impact of traditional and modern fertilization, radiological parameters and activity levels of ⁶Ra, Th, and ⁰K were determined for 27 oases. These oases were located in three southern Tunisian governorates. The activity concentration of ⁶Ra, Th, and ⁰K was measured using a 3 × 3 inch NaI(Tl) scintillation detector, which was found to be 21.

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Association of HLA class II alleles and haplotypes with bullous and mucus membrane pemphigoid risk: A systematic review, a meta-analysis and a meta-regression.

Int J Immunopathol Pharmacol

October 2024

Research Laboratory in Immunology of Renal Transplantation and Immunopathology (LR03SP01), Charles Nicolle Hospital, Tunis El Manar University, Bab Saadoun, Tunis, Tunisia.

Article Synopsis
  • Several studies have looked into the link between certain HLA Class II genes and the skin conditions bullous pemphigoid (BP) and mucous membrane pemphigoid (MMP), but their findings have been inconsistent and more investigation on study differences is needed.
  • A comprehensive review and meta-analysis of prior studies revealed that specific alleles (DQB1*0301, DRB1*1101, and others) significantly increase the risk for pemphigoid, especially when triggered by certain medications.
  • Additionally, the DQA1*0201 allele appears to reduce the risk of developing pemphigoid, indicating a potential protective effect against the disease.
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Validation of the Arabic version of the Adolescent Distress-Eustress Scale (ADES).

BMC Psychol

October 2024

The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry "Ibn Omrane", Razi Hospital, 2010, Manouba, Tunis, Tunisia.

Article Synopsis
  • The study evaluated the reliability and validity of an Arabic version of the Adolescent Distress-Eustress Scale (ADES) among high school students in Saudi Arabia, using statistical methods like confirmatory factor analysis and reliability scores.
  • A sample of 505 students (52.7% females) showed good internal consistency in measuring distress and eustress, with notable gender differences in scores.
  • Results indicated that the Arabic ADES is a reliable tool for assessing emotional distress and eustress in adolescents, with implications for its use in schools and mental health services for Arabic-speaking youth.
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Article Synopsis
  • * The research investigates the effects of adding paternal lymphocytes to maternal activated PBMCs during insemination, with patients divided into four groups based on the type and number of PBMCs used.
  • * Results indicate that using activated PBMCs increases clinical pregnancy rates across all groups, with the highest success observed in patients receiving both paternal and maternal activated PBMCs, achieving a clinical pregnancy rate of 47.2% and live birth rate of 41.
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Introduction: Injuries caused by terrorism attacks are one of the urgent problems of the society and the health system. In this work, we aimed to assess the injury severity score (ISS) and trauma injury severity score (TRISS) in Tunisian military combatants injured during terrorism attacks.

Materials And Methods: A total of 153 victims of terrorism admitted to the Military Hospital of Tunis between January 2012 and January 2017 were included.

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Association of four CTLA-4 gene polymorphisms with pemphigus risk: a systematic review, meta-analysis, and meta-regression.

J Int Med Res

October 2024

Research Laboratory in Immunology of Renal Transplantation and Immunopathology (LR03SP01), Charles Nicolle Hospital, Tunis El Manar University, Tunisia.

Article Synopsis
  • - The review focused on the impact of four specific single nucleotide polymorphisms (SNPs) in the CTLA-4 gene on the risk of developing pemphigus, an autoimmune skin disease.
  • - An extensive literature search was conducted across several databases, and meta-analyses determined that the SNPs rs5742909*C and rs733618*C significantly increased the risk of pemphigus, while the other two SNPs did not.
  • - The findings indicate a potential genetic link to pemphigus susceptibility, with implications for understanding the disease's biological mechanisms.
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  • - Adolescents are particularly vulnerable to insomnia and are more likely to experience psychotic symptoms, which can increase the risk of developing psychotic disorders in the future.
  • - A study involving 527 Lebanese adolescents found that insomnia severity influences the relationship between noise annoyance and psychotic disorders, indicating that teens sensitive to noise may be at higher risk if they also suffer from insomnia.
  • - The research highlights that at low to moderate insomnia levels, greater noise annoyance correlates with an increase in psychotic experiences, suggesting a complex interaction that could lead to better understanding of psychotic disorders in this age group.
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