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Circulating anti-pericyte autoantibodies are present in Type 2 diabetic patients and are associated with non-proliferative retinopathy.
Diabetologia
April 2003
Department of Ophthalmology, Tufts University School of Medicine, Tufts Center for Vision Research and New England Eye Center, Tufts-New England Medical Center (Box450), 750 Washington Street, MA 02111, Boston, USA.
Aims/hypothesis: This study aims to determine the prevalence of anti-pericyte autoantibodies in Type 2 diabetes and to characterize these autoantibodies as new markers of disease activity in diabetic retinopathy.
Methods: A total of 299 patients with Type 2 diabetes participated in this study. Retinopathy was assessed by 7-field stereo fundus photography and was graded according to the ETDRS scale.