Minimally Invasive Fixed Prosthodontics: A Narrative Review.

Objective: Minimally invasive dentistry is being widely practiced. The center stone is to be as conservative as possible to minimize unnecessary removal of healthy tooth structure. In prosthodontics the patients have generalized and combined nature of diseases.

Biomechanical Analysis of Truncated Cone Implants for Maxillary Sinus Lift: An In Vitro Study on Polyurethane Laminas.

This study aimed to evaluate the biomechanical performance of two truncated cone implant designs in maxillary sinus lift (MSL) procedures using polyurethane laminas. A total of 128 implants were used. Polyurethane laminas were divided into two groups based on thickness (1 and 3 mm) and two subgroups based on density (20 and 30 pounds per cubic foot, PCF).

Measurement of volumetric wear of printed polymer resin and milled polymer infused ceramic network definitive restorative materials.

Statement Of Problem: Currently there is no regulatory requirement or international standard for the wear resistance of dental materials and therefore no need to test prior to market launch.

Purpose: The purpose of this in vitro study was to evaluate and compare the total volumetric wear characteristics of milled polymer infiltrated ceramic network (MPICN) and printed polymer resin (PPR) as substrates opposing five antagonists, human enamel (EN), lithium disilicate (LD), zirconia (ZR), MPICN, and PPR, and to evaluate and compare the volumetric wear of these same materials as antagonists.

Material And Methods: Ten of each antagonist for a total of 50 EN, LD (IPS e.

Classification of Scanning Errors of Digital Scans Recorded by Using Intraoral Scanners.

Objectives: The different scanning errors that can be caused by the operator handling an intraoral scanner (IOS) or the intraoral conditions of the patient being scanned have not been described. The purpose of this review was to describe and classify the scanning errors that can be identified in digital scans recorded by using IOSs.

Overview: The identification of scanning errors in an intraoral scan and understanding the cause of these scanning errors are fundamental procedures for successfully handling an IOS and integrating these digital data acquisition technologies in dental practices.

International Expert-Based Consensus Definition, Classification Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Inter-Disciplinary Modified Delphi Study.

Purpose: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and at least 16 classification systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely under-diagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ.

Influence of edentulous areas on the accuracy of the maximum intercuspal position recorded by using different intraoral scanners or an artificial intelligence-based program.

Statement Of Problem: Intraoral scans can be articulated in maximum intercuspal position (MIP) by using an artificial intelligence (AI) based program; however, the impact of edentulous areas on the accuracy of the MIP located using this AI-based program is unknown.

Purpose: The purpose of this in vitro study was to assess the impact of edentulous areas (0, 1, 2, 3, and 4 posterior mandibular teeth) on the accuracy of the MIP located using 3 intraoral scanners (IOSs) and an AI-based program.

Material And Methods: Stone casts articulated in MIP in an articulator were digitized (T710).

Familial Oculoauriculovertebral Spectrum: A Genomic Investigation of Autosomal Dominant Inheritance.

Objective: Oculoauriculovertebral spectrum (OAVS) encompasses abnormalities on derivatives from the first and second pharyngeal arches including macrostomia, hemifacial microsomia, micrognathia, preauricular tags, ocular, and vertebral anomalies. We present genetic findings on a 3-generation family affected with macrostomia, preauricular tags and ptosis following an autosomal dominant pattern.

Design: We generated whole-genome sequencing data for the proband, affected father, and unaffected paternal grandmother followed by Sanger sequencing on 23 family members for the top candidate gene mutations.

Accuracy (trueness and precision) of 3-dimensional virtual patients: An in vitro investigation of different facial scanners and digital integration techniques.

Objectives: To investigate the influence of different facial scanners and integration approaches on the accuracy of virtual dental patients (VDPs).

Methods: Forty VDPs were generated using a head mannequin and two facial scanners: 1) an industrial scanner and 2) a smartphone scanner. For each scanner, two integration methods were applied: 1) integration by virtual facebow scan and 2) integration by nose-teeth scan.

Performance evaluation of a machine learning-based methodology using dynamical features to detect nonwear intervals in actigraphy data in a free-living setting.

Goal And Aims: One challenge using wearable sensors is nonwear time. Without a nonwear (e.g.

Association Between Severe Periodontitis and Cognitive Decline in Older Adults.

(1) Background: Periodontal disease, a progressive inflammatory condition, disrupts the oral microbiome and releases inflammatory cytokines, leading to systemic issues, including cognitive decline. This study investigates the association between severe periodontitis and cognitive decline, exploring the role of alkaline phosphatase (ALP), an enzyme linked to systemic inflammation, as an effect modifier. (2) Methods: We analyzed cross-sectional data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES).

Long-Term Success of Dental Implants in Atrophic Maxillae: A 3-Year Case Series Using Hydroxyapatite and L-PRF.

Dental implants are essential for the prosthetic rehabilitation of edentulous patients, requiring adequate bone volume and density for osseointegration and load support. The posterior region of the maxilla, commonly deficient in bone quality and quantity, represents a clinical challenge. This case series reports an analysis involving 69 dental implants in the atrophic maxilla of nine patients.

Prevalence of Obesity and Dental Caries in Kindergarten Children During the First Decade of Saudi Vision 2030: A Cross-Sectional Study.

Background/objectives: Obesity and dental caries are significant health issues affecting children worldwide. This study aims to investigate the prevalence of obesity and dental caries among kindergarten children in Saudi Arabia during the early implementation years of the Vision 2030 initiative. Specifically, it examines the obesity rates between public and private kindergartens and assesses the correlation between obesity and caries risk.

Substituting the Conventional Facebow With an Extraoral Scan Body System for Transferring the Maxillary Cast Into the Virtual Articulator: Manufacturing Procedures and Digital Clinical Protocol.

Clinical Considerations: Conventional facebow records are used to transfer the maxillary cast into the analog articulator. Different reference planes have been described, including the true horizontal or gravity reference plane. A conventional facebow (Kois Dentofacial Analyzer; Panadent) allows the recording of the gravity plane for transferring the maxillary cast into the analog semi-adjustable articulator.

The Effectiveness of Platelet Rich Fibrin in Alveolar Ridge Reconstructive or Guided Bone Regenerative Procedures: A Systematic Review and Meta-Analysis.

Introduction And Objectives: Clinical studies have shown favorable outcomes following use of platelet rich fibrin (PRF), either alone or in conjunction with biomaterials for alveolar ridge reconstruction (ARR) or guided bone regeneration (GBR) . While PRF application accelerates wound healing and reduces postoperative discomfort, its effects on the alveolar bone gain, as part of ARR or GBR is less clear. Therefore, this study aims to investigate the clinical effectiveness of PRF when used in ARR or GBR, as well as postoperative discomfort following these procedures.

In vivo bioengineered tooth formation using decellularized tooth bud extracellular matrix scaffolds.

The use of dental implants to replace lost or damaged teeth has become increasingly widespread due to their reported high survival and success rates. In reality, the long-term survival of dental implants remains a health concern, based on their short-term predicted survival of ~15 years, significant potential for jawbone resorption, and risk of peri-implantitis. The ability to create functional bioengineered teeth, composed of living tissues with properties similar to those of natural teeth, would be a significant improvement over currently used synthetic titanium implants.

Effects of Platelet-Rich Fibrin on Bone Healing Around Implants Placed in Maxillary Sinuses: A Histomorphometric Assessment in Rabbits.

This study investigated the effect of platelet-rich fibrin (PRF) on bone healing around implants placed in elevated sinus cavities. Forty New Zealand albino rabbits were divided into eight groups, based on the time of sacrifice (14 or 40 days) and the material used: blood clot (control), hydroxyapatite (HA) from bovine bone, HA combined with PRF, and PRF alone. Each group consisted of five animals (n = 5).

Is There an Ideal Concentration of Ozonized Oil for the Prevention and Modulation of Zoledronate-Induced Mandibular Osteonecrosis? A Study on Senescent Rats.

This study aimed to identify whether there is an ideal concentration for applying ozonized oil (OZ) in the post-exodontic alveoli of senescent rats treated with zoledronate (ZOL). Thirty-five female rats, aged 18 months, were divided into five groups: ZOL; ZOL+OZ500; ZOL+OZ600; ZOL+OZ700; and SAL. The groups treated with ZOL, and other concentrations of OZ received applications at a dose of 100 μg/kg, while the SAL group received saline.

Modified Periosteal Releasing Incision (MPRI) for Primary Closure: Visualization of the Mental Nerve.

Periodontal procedures often require flap advancement for adequate coverage of the surgical site, with tension-free primary closure essential for successful outcomes. Although the periosteal releasing incision is frequently performed, it may necessitate deeper or more incisions, which could result in consequences such as edema, bleeding, paresthesia, and discomfort for the patient. To address these issues, the modified periosteal releasing incision was proposed to minimize trauma into the submucosa.

Multiancestry Genome-Wide Association Study of Early Childhood Caries.

Early childhood caries (ECC) is the most common noncommunicable childhood disease-an important health problem with known environmental and social/behavioral influences lacking consensus genetic risk loci. To address this knowledge gap, we conducted a genome-wide association study of ECC in a multiancestry population of U.S.

LL-37 regulates odontogenic differentiation of dental pulp stem cells in an inflammatory microenvironment.

Background: Inflammation often causes irreversible damage to dental pulp tissue. Dental pulp stem cells (DPSCs), which have multidirectional differentiation ability, play critical roles in the repair and regeneration of pulp tissue. However, the presence of proinflammatory factors can affect DPSCs proliferation, differentiation, migration, and other functions.

Metabolic and Regulatory Pathways Involved in the Anticancer Activity of Perillyl Alcohol: A Scoping Review of In Vitro Studies.

Background/objectives: Perillyl alcohol (POH), a plant-derived compound, has demonstrated anti-tumor activity across various human cancers. Understanding the regulatory pathways through which POH exerts its effects is crucial for identifying new therapeutic opportunities and exploring potential drug repositioning strategies. Therefore, this scoping review aims to provide a comprehensive overview of the metabolic and regulatory pathways involved in the anticancer effects of POH, based on in vitro evidence.

Accuracy of Intraoral Scanner Systems for Fabricating Inlay, Onlay, and Veneer Restorations: A Systematic Review and Meta-Analysis.

Purpose: To evaluate the accuracy of intraoral scanners (IOSs) for fabricating inlay, onlay, and veneer restorations.

Materials And Methods: A literature search was completed in five databases: PubMed/Medline, Scopus, Embase, Web of Science, and Cochrane. A manual search was also conducted.