2 results match your criteria: "Tufts Center for Vision Research and New England Eye Center[Affiliation]"

Aims: To determine whether albuminuria, hypertension, or HbA 1c are independently associated with antipericyte autoantibodies (APAAs) in type 2 diabetes mellitus.

Methods: Two hundred ninety-nine subjects with different degrees of retinopathy according to the Early Treatment Diabetic Retinopathy Study Scale participated in this study. Albuminuria was defined as an albumin/creatinine ratio above the normal cutoff limit, that is, 2.

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Circulating anti-pericyte autoantibodies are present in Type 2 diabetic patients and are associated with non-proliferative retinopathy.

Diabetologia

April 2003

Department of Ophthalmology, Tufts University School of Medicine, Tufts Center for Vision Research and New England Eye Center, Tufts-New England Medical Center (Box450), 750 Washington Street, MA 02111, Boston, USA.

Aims/hypothesis: This study aims to determine the prevalence of anti-pericyte autoantibodies in Type 2 diabetes and to characterize these autoantibodies as new markers of disease activity in diabetic retinopathy.

Methods: A total of 299 patients with Type 2 diabetes participated in this study. Retinopathy was assessed by 7-field stereo fundus photography and was graded according to the ETDRS scale.

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