2,746 results match your criteria: "Tuberous Sclerosis Imaging"
Med Phys
December 2024
Department of Radiology, University of Missouri, Columbia, Missouri, USA.
World J Urol
September 2024
Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, 1 Shuaifuyuan Wangfujing, Dongcheng, Beijing, 100730, PR China.
Background: We aimed to launched new staging criteria to predict mTOR inhibitors treatment effect of renal angiomyolipomas (r-AMLs) in TSC patients.
Methods: 40 TSC patients with 69 r-AMLs were divided into two groups based on the efficacy of 6-month mTOR inhibitor treatment. Epidemiological data, therapeutic response, and predictive factors of enrolled patients were collected and analyzed.
World Neurosurg
December 2024
Department of Neurosurgery, Santobono-Pausilipon Children's Hospital, AORN, Naples, Italy.
Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) is a new minimally invasive treatment for tuberous sclerosis complex (TSC)-associated epilepsy in children. This video describes a case of a 17-year-old girl with TSC-associated drug-resistant epilepsy treated with robotic-assisted MRgLITT. In our case, MRgLITT was safe and effective in simultaneous targeting of multiple epileptic tubers in 1 single procedure, leading to a marked decrease in seizure frequency.
View Article and Find Full Text PDFCancer Med
September 2024
Department of Urology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Objectives: To assess the efficacy and safety of preoperative neoadjuvant everolimus in renal angiomyolipomas (AML) patients with or without Tuberous Sclerosis Complex (TSC).
Materials And Methods: This multi-institutional retrospective study enrolled renal AML patients who underwent partial nephrectomy (PN) or total nephrectomy after receiving at least 1 month of pre-operative everolimus. Imaging evaluations were collected before and after treatment, along with demographic, surgical, and follow-up information.
Am J Med Genet A
January 2025
Massachusetts General Hospital, Boston, Massachusetts, USA.
Abdom Radiol (NY)
September 2024
Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Hereditary renal mass syndromes, although rare, account for at least 3-5% of kidney cancers and significantly impact affected families. Accurate diagnosis and management by radiologists are crucial as these syndromes often present at imaging with both renal and extra-renal manifestations. The radiologist may be the first to recognize these stigmata at imaging, some of which satisfy major features for diagnosis and obviate the need for genetic testing.
View Article and Find Full Text PDFTuberous sclerosis (TSC) is an autosomal dominant neurocutaneous disorder. This case highlights rare isolated neurologic finding in a TSC patient emphasizing the need for heightened suspicion even in the absence of any cutaneous findings and family history.
View Article and Find Full Text PDFEur Heart J Imaging Methods Pract
July 2024
Cardiovascular Directorate, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, London SE1 7EH, UK.
Medicina (Kaunas)
August 2024
Department of Urology, Peking University Third Hospital, Beijing 100191, China.
Arch Dermatol Res
August 2024
Department of Dermatology and Venereology, Faculty of Medicine, Tanta University Hospital, 31527, Al-Bahr St., Tanta, Egypt.
Acta Neurochir (Wien)
August 2024
Department of Neurosurgery, Copenhagen University Hospital, Copenhagen, Denmark.
Prenat Diagn
September 2024
Maternal Fetal Care Center, Division of Fetal Medicine and Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lancet
August 2024
Barts Heart Centre, Barts Health NHS Trust, London, UK.
Ultrasound Obstet Gynecol
September 2024
Department of Paediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Epilepsy Res
September 2024
Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address:
Ninety percent of tuberous sclerosis complex (TSC) patients have seizures, with ∼50 % developing drug refractory epilepsy. Surgical intervention aims to remove the seizure onset zone (SOZ). This retrospective study investigated the relationship of SOZ size, ictal pattern, and extent of resection with surgical outcomes.
View Article and Find Full Text PDFCureus
August 2024
Department of General, Vascular, Endocrine and Transplant Surgery, Medical University of Warsaw, Warsaw, POL.
A renal angiomyolipoma (AML) is a rare, usually benign tumor consisting of smooth muscle cells, abnormal blood vessels, and fat tissue. Although AMLs are often asymptomatic, they can present with flank pain, hematuria, and a palpable mass in the abdomen. A significant complication involves rupture and hemorrhage into the retroperitoneal cavity, which can be life-threatening.
View Article and Find Full Text PDFOphthalmic Surg Lasers Imaging Retina
October 2024
Background And Objective: We used a multi-modal imaging approach including fundus fluorescein angiography (FFA) to assess the retinal lesions in tuberous sclerosis complex (TSC) and evaluate their correlation with intracranial tuber burden on magnetic resonance imaging (MRI).
Patients And Methods: Participants with TSC underwent bilateral fundus photography, optical coherence tomography (OCT), infrared (IR) imaging, and FFA. Participants' most recent MRI brain scans were analyzed to determine intracranial tuber load.
Int J Rheum Dis
July 2024
Department of Rheumatology, Hospital Clínic, University of Barcelona, Barcelona, Spain.
J Med Case Rep
July 2024
Radiotherapy Department, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Background: Subependymal giant cell astrocytoma is a benign brain tumor that occurs in patients with tuberous sclerosis complex. Surgical removal is the traditional treatment, and expert opinion is strongly against the use of radiotherapy. Recently, success has been reported with the mTor inhibitor everolimus in reducing tumor volume, but regrowth has been observed after dose reduction or cessation.
View Article and Find Full Text PDFiScience
July 2024
Department of Microbiology and Molecular Genetics, School of Medicine, University of California Irvine, Irvine, CA, USA.
Epilepsia Open
October 2024
Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), R. Santa Comba, University of Coimbra, Coimbra, Portugal.
Arch Gynecol Obstet
September 2024
Department of Ultrasound in Medicine, Hangzhou Women's Hospital, Hangzhou, Zhejiang, China.
Radiol Case Rep
September 2024
Neuroradiology department- Ibn Sina University hospital, Rabat, Morocco.