1 results match your criteria: "Trinity College Dublin and Dublin Dental University Hospital (DDUH).[Affiliation]"
Eur J Cancer Prev
March 2021
School of Dental Science, Trinity College Dublin and Dublin Dental University Hospital (DDUH).
Background: Since the serendipitous discovery of bovine α-lactalbumin made lethal to tumour cells (BAMLET)/human α-lactalbumin made lethal to tumour cells there has been an increased interest in the ability of the two components, oleic acid and α-lactalbumin, to form anti-cancer complexes. Here we have investigated the in-vitro efficacy of the BAMLET complex in killing oral cancer (OC) cells, determined the active component of the complex and investigated possible biological mechanisms.
Materials And Methods: Two OC cell lines (±p53 mutation) and one dysplastic cell line were used as a model of progressive oral carcinogenesis.