5,389 results match your criteria: "Tricuspid Stenosis"

Quantification of right ventricular (RV) size and function after tetralogy of Fallot repair is critical for determining timing of reintervention and outcomes. Tetralogy of Fallot patients with pulmonary atresia and major aortopulmonary collateral arteries (TOF/PA/MAPCAs) are a unique group in which the RV is subjected to various loading conditions, allowing for direct comparison. Retrospective evaluation of RV echocardiographic indices in repaired pediatric TOF/PA/MAPCAs patients (2/2002 - 4/2018).

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Objective: We sought to assess whether post-implant transcatheter aortic valve prosthesis multi detector computed characteristics differ between patients with native tricuspid and bicuspid aortic valve stenosis, as well as the effect on valve performance and clinical implications.

Methods: We analysed 100 consecutive post-implant multi detector computed tomography scans to assess self-expandable prosthesis non-uniform expansion at six pre-specified valvular levels, and other specific parameters, including valvular and perivalvular thrombosis at six months follow-up. Echocardiographic prosthesis performance and clinical outcome was also evaluated.

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Article Synopsis
  • * Postmortem examinations showed that the manatee suffered from various health issues, including aortic stenosis, left ventricular hypertrophy, and a plastic bag lodged in its esophagus, alongside cold stress symptoms.
  • * Blood tests indicated systemic inflammation and potential coagulation problems, while heart-related findings included severe cardiac abnormalities; however, the exact cause of these cardiovascular issues remains undetermined.
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  • - This study examined the diagnosis and treatment of valvular heart disease (VHD) in Korea, focusing on adult patients with moderate to severe cases through echocardiography in 45 hospitals.
  • - Out of 4,094 patients, about 1,482 had severe VHD, with varied rates of intervention depending on the type of valve issue, highlighting significant in-hospital mortality, especially for secondary severe mitral regurgitation (9.0%).
  • - The findings reveal a 5.4% overall in-hospital mortality rate, with lower mortality in patients who underwent surgical or transcatheter interventions compared to those receiving conservative treatment, suggesting the need for improved VHD management strategies in the future.
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Background: Tricuspid regurgitation (TR) and mitral regurgitation (MR) are common valvular conditions encountered in patients undergoing transcatheter aortic valve replacement (TAVR). This retrospective study investigates the impact of moderate or severe TR and MR on all-cause mortality in 1-year post-TAVR patients.

Methods: Consecutive patients who underwent TAVR at the 3 academic tertiary care centers in our health system between 2012 and 2018 were identified.

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Psoriasis and risk of new-onset degenerative valvular heart disease: a prospective cohort study.

Eur Heart J Qual Care Clin Outcomes

November 2024

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing 100037, China.

Article Synopsis
  • The study investigates the relationship between psoriasis and degenerative valvular heart disease (VHD), finding that both share common risk factors and inflammatory conditions.
  • Utilizing data from the UK Biobank, researchers analyzed the incidence of various types of VHD among participants with and without psoriasis over a median follow-up period of around 13.7 years.
  • Results showed that participants with psoriasis had a higher risk of developing aortic stenosis (AS), particularly among women, whereas no significant links were found for other forms of degenerative VHD.
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  • The study compares the survival rates and durability between porcine and pericardial prostheses used in tricuspid valve replacement over a period from 1975 to 2022.
  • Results show no significant differences in 10-year survival rates, cumulative incidence of structural valve deterioration, or reoperation rates between the two types of valves.
  • The findings suggest that both valve types are equally effective, indicating that the choice of valve may be based on other factors rather than survival or durability outcomes.
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Article Synopsis
  • * Transcatheter aortic valve replacement (TAVR) has shown similar outcomes in selected patients with bicuspid and tricuspid pathology, which raises questions about its effectiveness in younger patients with longer life expectancies.
  • * Future research needs well-designed randomized controlled trials to determine the best treatment for bicuspid aortic stenosis, and there's uncertainty about how to approach patient enrollment in these studies.
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Carcinoid heart findings in vasoactive intestinal peptide-secreting tumour.

BMJ Case Rep

November 2024

Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.

Article Synopsis
  • - Diagnosis of tricuspid valve disease in patients with carcinoid heart syndrome is often done with echocardiography, especially in those already diagnosed with carcinoid syndrome.
  • - VIPoma is a rare type of tumor occurring in 0.05%-2% of cases, causing symptoms like flushing, diarrhea, and electrolyte issues without typically affecting heart valves.
  • - In a notable case, detection of tricuspid regurgitation and stenosis during echocardiography led to a quicker investigation for cancer, ultimately revealing the presence of VIPoma.
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Article Synopsis
  • - Transcatheter aortic valve replacement (TAVR) has greatly improved aortic valve disease treatment but has highlighted the lack of effective solutions for concurrent tricuspid valve disease.
  • - The review discusses new methods for transcatheter tricuspid valve interventions (TTVI) after TAVR, such as repair, replacement, annuloplasty, and edge-to-edge repair.
  • - It emphasizes the importance of interdisciplinary collaboration to enhance patient selection and tackle procedural challenges as the field of TTVI evolves.
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Article Synopsis
  • This study investigates how right ventricular (RV) dysfunction affects the outcomes of patients with low-flow, low-gradient aortic stenosis (LFLG-AS) who are undergoing transcatheter aortic valve replacement (TAVR).
  • Utilizing data from two Italian centers, it was found that RV dysfunction is linked to a significantly increased risk of all-cause death and major cardiovascular events after one year.
  • The findings suggest that assessing RV dysfunction before TAVR can enhance the ability to predict patient prognosis.
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Article Synopsis
  • - This study examined the effects of transcatheter aortic valve replacement (TAVR) on patients with heart failure and moderate aortic stenosis, comparing TAVR with clinical surveillance followed by valve replacement if the condition worsened.
  • - A total of 178 patients were randomly assigned to either TAVR or surveillance, and results indicated that TAVR was associated with better clinical outcomes, though the statistical significance was borderline.
  • - TAVR led to a more substantial improvement in heart failure symptoms, as measured by the Kansas City Cardiomyopathy Questionnaire, compared to the surveillance group after one year of follow-up.
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Article Synopsis
  • This study investigates the long-term durability of bioprosthetic valves in patients with bicuspid aortic valve (BAV) after undergoing transcatheter aortic valve replacement (TAVR), compared to patients with tricuspid aortic valve (TAV).
  • A total of 170 BAV and 145 TAV patients were followed for an average of over 5 years, showing no significant differences in rates of structural valve deterioration or bioprosthetic valve failure between the two groups.
  • The findings suggest that TAVR provides satisfactory long-term valve performance for patients with BAV, comparable to those with TAV, indicating good outcomes for both groups.
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Article Synopsis
  • The study focuses on severe aortic stenosis (AS), particularly the paradoxical low-flow low-gradient (PLF-LG) type, which has unique characteristics and uncertain management and prognosis.
  • It analyzed 205 patients diagnosed with severe AS at a hospital in 2021, categorizing them into four groups: high gradient (HG), concordant low-flow low-gradient (CLF-LG), PLF-LG, and normal-flow low-gradient (NF-LG).
  • Findings indicated that PLF-LG patients had a significantly higher mortality rate despite similar intervention rates compared to those with high gradient AS, suggesting a need for closer monitoring and early intervention for this group.
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Early surgical outcomes of rapid deployment aortic valve replacement in bicuspid aortic valves.

J Thorac Dis

September 2024

Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Article Synopsis
  • This study investigates the outcomes of rapid-deployment aortic valve replacement (RD AVR) in patients with bicuspid aortic valves (BAV) compared to those with tricuspid aortic valves (TAV), aiming to fill the gap in existing research.
  • The analysis included 80 patients, with 30 undergoing RD AVR; 16 had TAV and 14 had BAV, allowing for a thorough comparison of preoperative and postoperative outcomes.
  • Results showed significant differences in postoperative pressure gradients favoring the BAV group, with no severe complications reported, although one BAV patient required a pacemaker, indicating generally good safety and feasibility for BAV patients undergoing RD AVR.
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Background: This study aimed to compare the incidence and prognostic implications of new-onset conduction disturbances after surgical aortic valve replacement (SAVR) in patients with bicuspid aortic valve (BAV) aortic stenosis (AS) versus patients with tricuspid aortic valve (TAV) AS (ie, BAV-AS and TAV-AS, respectively). Additionally, the study included stratification of BAV patients according to subtype.

Methods: In this cohort study, the incidence of postoperative third-degree atrioventricular (AV) block with subsequent permanent pacemaker requirement and new-onset left bundle-branch block (LBBB) was investigated in 1147 consecutive patients without preoperative conduction disorder who underwent isolated SAVR (with or without ascending aortic surgery) between January 1, 2005, and December 31, 2022.

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Article Synopsis
  • - The study examined ultrasound findings and SNP-array results for fetuses with 17q12 deletions and duplications during the second and third trimesters, focusing on prenatal characteristics and outcomes.
  • - Data from 16 fetuses with deletions and 7 with duplications were analyzed, revealing significant abnormalities; deletions often led to renal issues, while duplications were associated with cardiovascular and gastrointestinal problems.
  • - Out of the pregnancies, 9 were terminated, while 14 continued; some cases presented multiple severe structural malformations, highlighting the complexity of conditions associated with these genetic variations.
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[Clinical characteristics of patients with moderate or severe valvular heart disease].

Zhonghua Xin Xue Guan Bing Za Zhi

October 2024

Department of Cardiovascular Medicine, Center for Circadian Metabolism and Cardiovascular Disease, Key Laboratory of Geriatric Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Southwest Hospital, Army Medical University, Chongqing 400038, China.

Article Synopsis
  • This study aimed to explore the characteristics, causes, and patterns of patients with moderate to severe valvular heart disease (VHD) using data from Southwest Hospital between 2001 and 2020.
  • A total of 68,354 patients were analyzed, revealing an average age of 63 years, with 52.24% being female; age patterns showed a peak incidence in the 65-69 age group.
  • The analysis indicated differences in gender distribution for specific VHD types, with female patients showing higher rates of certain conditions, and rheumatic VHD represented a higher percentage than degenerative VHD among the patients studied.
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Effect of aortic valve phenotype and sex on aorta dilation in patients with aortic stenosis.

Open Heart

October 2024

Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada

Article Synopsis
  • Bicuspid aortic valve (BAV) shows increased progression of aorta dilation compared to tricuspid aortic valve (TAV) in patients with aortic stenosis, with a median annualized change of 0.33 mm/year for BAV versus 0.21 mm/year for TAV.
  • Factors influencing the dilation rate differ by valve type; BAV patients are more affected by low-density lipoprotein (LDL) levels, while TAV patients are influenced by the apolipoprotein B/A-I ratio and baseline aortic jet velocity.
  • The study highlights that men and women have different predictors for AA dilation; men’s dilation relates to baseline jet velocity and aortic diameter, while
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