883 results match your criteria: "Trichosporon Infections"
Assessment of pathogenic yeast species in the oral cavity of dogs: Antifungal susceptibility and implications for human health.
Res Vet Sci
December 2024
Programa de Pós-Graduação Stricto sensu em Biociência Animal, Universidade de Cuiabá (UNIC), Cuiabá, MT, Brazil.
Companions' animals can present a risk for the transmission of opportunistic diseases to their owners, including those caused by yeasts of the Candida genus residing in their oral microbiota. This study aimed to isolate and identify yeasts from the oral cavity of dogs and assess their susceptibility to antifungals. Yeast species were identified using automated methods MALDI-TOF-MS and VITEK 2 from 50 dogs (aged 2-4 years, various breeds).
View Article and Find Full Text PDFIdentification of the cell-surface lectin domain-containing protein expressed in the adhesive colony morphology of Trichosporon asahii.
Med Mycol
December 2024
Department of Microbiology and Immunology, Faculty of Pharmaceutical Sciences, Shonan University of Medical Sciences, Japan.
Trichosporon asahii is a yeast pathogen that causes a deep-seated infection. In fungal infections, molecules involved in adhesion to host tissues or catheters are one of the pathogenic factors. A single strain of T.
View Article and Find Full Text PDFTrichosporon infection in chronic kidney disease patients from a tertiary care hospital - a case series or an outbreak? An unanswered question but a well-managed problem.
GMS Infect Dis
November 2024
Department of Community Medicine, Government Medical College, Thiruvananthapuram, India.
While the majority of spp. isolated in clinical laboratories are typically associated with episodes of colonization or superficial infections, this fungal species has gained recognition as an opportunistic pathogen, leading to invasive infections worldwide. In this article, we present a case series of spp.
View Article and Find Full Text PDFIdentification of fungal pathogens among COVID-19 and non COVID-19 cases in Bhaktapur hospital, Nepal.
BMC Res Notes
November 2024
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Article Synopsis
- COVID-19 patients are at a higher risk for fungal infections, prompting a study to identify fungal pathogens in both COVID positive and negative patients, as well as assess their antifungal resistance and biofilm formation abilities.
- The study found a 6.70% prevalence of fungal pathogens in COVID-positive cases and 22.77% in negative cases, with Candida albicans being the most common pathogen identified.
- Results indicated that most Candida species were susceptible to miconazole but resistant to ketoconazole, highlighting the need for increased awareness and antifungal susceptibility testing in clinical settings.
Role of Hog1-mediated stress tolerance in biofilm formation by the pathogenic fungus Trichosporon asahii.
Sci Rep
November 2024
Department of Microbiology, Meiji Pharmaceutical University, 2-522-1, Noshio, Kiyose, Tokyo, 204-8588, Japan.
Article Synopsis
- Trichosporon asahii is a fungus that can cause bloodstream infections in immunocompromised patients, especially those with low white blood cell counts (neutropenia).
- The fungus can switch between yeast and hyphal forms, forming biofilms on medical devices like catheters, a process potentially influenced by a protein called Hog1.
- Research revealed that a mutant strain of T. asahii lacking the hog1 gene produced more biofilm in rich lab conditions but less in living models like silkworms, indicating that Hog1 plays a crucial role in biofilm formation under different environmental stresses.
Emerging Fungal Infections of the Central Nervous System in the Past Decade: A Literature Review.
Infect Dis Rep
October 2024
Infectious Diseases Department, Hospital de São João-Unidade Local de Saúde São João, 4200-319 Porto, Portugal.
Article Synopsis
- Invasive fungal infections in the central nervous system (CNS) are a growing health issue linked to high mortality, largely due to an increase in immunocompromised individuals and better diagnostic tools.
- This article aims to highlight emerging fungal pathogens causing CNS infections and their clinical characteristics through a review of recent literature.
- The findings indicate a rise in reported cases from various fungi, emphasizing the urgent need for better diagnostic and treatment strategies to combat these serious infections.
[Infection of Aspergillus fumigatus after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia: 2 cases report and literature review].
Zhonghua Xue Ye Xue Za Zhi
September 2024
Department of Transplantation, Beijing Ludaopei Hospital, Beijing 100176, China.
Article Synopsis
- - Rising cases of rare yeast infections, like Trichosporon asahii, are linked to more immunocompromised patients following hematopoietic stem cell transplants.
- - A multidisciplinary approach is crucial for effectively managing these complex infections to enhance patient outcomes.
- - Early screening for infection spread and prompt, combined treatment strategies may improve prognosis for affected individuals.
Optimization of the Diagnosis of Central Nervous System Infections in Vietnamese Hospitals: Results From a Retrospective Multicenter Study.
Open Forum Infect Dis
September 2024
Institute of Tropical Medicine, Universitätsklinikum Tübingen, Tübingen, Germany.
Article Synopsis
- * A study in Vietnam involving 330 patients compared the BioFire FilmArray Meningitis/Encephalitis (FAME) Panel to traditional diagnostic methods, with FAME showing an 87% agreement rate and detecting 19% of specimens.
- * While FAME offers rapid pathogen detection, it's not a complete replacement for traditional methods and should be tailored to local disease patterns to improve healthcare outcomes.
Snakes as sentinel of zoonotic yeasts and bio-indicators of environmental quality.
Sci Rep
September 2024
Department of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Reptiles in the wild or as pets may act as spreaders of bacteria, viruses, fungi and parasites. However, studies on the mycobiota of these animals are scanty. This study investigates the occurrence of yeasts from the cloacal swabs of snakes of different origins and the antifungal profile of the isolated strains.
View Article and Find Full Text PDFIdentification of Trichosporon yeast isolates from superficial infections in male patients from Central Brazil: an approach to the diversity of infections caused by this basidiomycete fungus.
Braz J Biol
September 2024
Secretaria de Saúde, PPG em Ciências, Coordenação de Controle de Doenças (PPG-CCD-SES), São Paulo, SP, Brasil.
Article Synopsis
- The study focuses on Trichosporon fungi, which can cause skin infections and serious diseases, particularly in certain populations in Central-West Brazil.
- Researchers isolated 25 strains, with the most common being T. asahii, and found that skin infections were particularly prevalent in males aged 21-30, especially among black men.
- Identification of the Trichosporon species involved a combination of traditional phenotypic methods and advanced molecular techniques, specifically analyzing DNA sequences.
Neonatal Fungemia by Non-Candida Rare Opportunistic Yeasts: A Systematic Review of Literature.
Int J Mol Sci
August 2024
Neonatal Intensive Care Unit, General Hospital of Nikaia "Agios Panteleimon", 18454 Piraeus, Greece.
Article Synopsis
- Diagnosis and treatment are challenging due to limited information on antifungal effectiveness and the complexity of identifying emerging opportunistic yeast pathogens.
- The study found significant risk factors such as low birth weight, central catheter use, prematurity, and antibiotics, highlighting the urgent need for early detection and tailored treatments for affected neonates.
The Brief Case: Tricky in the urinary tract.
J Clin Microbiol
September 2024
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Photodynamic therapy combined with voriconazole of extensive ulcer caused by Trichosporon asahii.
Photodiagnosis Photodyn Ther
October 2024
Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, China; Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou 510095, China. Electronic address:
Article Synopsis
- Trichosporon species are normally found in humans but can lead to infections in both healthy and weakened immune systems, with T. asahii causing rare giant ulcers in healthy individuals.
- Treatment of these ulcers is complicated by drug resistance and the ability of the fungi to form biofilms.
- A case study showed that a large ulcer from T. asahii healed completely with a combination of photodynamic therapy (PDT) and the antifungal voriconazole, suggesting this method could work for similar tough infections.
White Piedra: More Than Trichosporon Species Infection.
Mycopathologia
August 2024
Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
Identification of causative fungus from sterile abscess using metagenomics followed by in situ hybridization.
Access Microbiol
August 2024
Department of Infection Metagenomics, Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan.
Article Synopsis
- Early diagnosis is crucial for treating invasive fungal infections, which are challenging to identify especially from sterile abscess biopsies.
- A case study on a 65-year-old Japanese male with acute myeloid leukemia showed that despite antifungal prophylaxis, no fungi were detected in blood cultures, but fragmented fungi were found in a liver biopsy and spleen abscess.
- Retrospective analyses and deep sequencing of the fungal genome allowed identification of the causative fungus, confirmed through hybridization with a DNA probe.
Microevolution during Chronic Infection May Lead to Coexist with the Host.
Dermatol Res Pract
July 2024
Department of Dermatology The Seventh Medical Center of PLA General Hospital, Beijing, China.
Article Synopsis
- The study focuses on a type of fungus that normally lives on human skin but can cause deadly infections, exploring how it changes over time during chronic infections.
- Two strains of this fungus were collected from a patient over a 15-year period to analyze microevolutionary changes using various methods, including immune response tests and gene expression analysis.
- Results showed that the later strain of fungus caused less immune response and had altered gene activity, suggesting it became less harmful over time, allowing it to coexist more easily with the host.
Rhinocerebral mucormycosis and Trichosporon asahii fungemia in a pediatric patient with acute lymphoblastic leukemia: a rare coinfection.
Rev Inst Med Trop Sao Paulo
July 2024
Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Department of Laboratory Medicine, Nanning, Guangxi, China.
Article Synopsis
- The patient developed a severe case of T. asahii fungemia along with rhinocerebral mucormycosis following infection by Pseudomonas aeruginosa, leading to significant health complications and ultimately death.
- This case highlights the need for multidisciplinary treatment strategies and ongoing research to improve understanding and management of complex infections like mucormycosis and T. asahii coinfection.
Real-time application of ITS and D1-D3 nanopore amplicon metagenomic sequencing in fungal infections: Enhancing fungal infection diagnostics.
Int J Med Microbiol
September 2024
Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
Article Synopsis
- Fungal infections have high rates of illness and death, but current diagnostic tests aren't very effective, prompting the exploration of advanced techniques like nanopore amplicon metagenomic sequencing.* -
- In this study involving 84 samples from 73 patients, a comparison was made between conventional fungal assays and sequencing results, revealing that sequencing was more effective in detecting rare fungi and had a shorter turnaround time.* -
- Overall, the study found that nanopore amplicon sequencing not only led to faster results (almost 5 days quicker) but also identified more uncommon fungal infections than traditional methods, highlighting its potential for clinical use.*
Fungemia due to opportunistic fungi in patients with cancer.
Rev Iberoam Micol
October 2024
Infectious Diseases Department, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico. Electronic address:
Background: Fungemia due to uncommon fungi and secondary to multiple risk factors has become an emergent health problem, particularly in oncology patients.
Aims: This study shows the following data collected during an 11-year period in a tertiary care oncologic center from patients with fungemia: demographic data, clinical characteristics, and outcome.
Methods: A retrospective study was performed at Instituto Nacional de Cancerología, a 135-bed referral cancer center in Mexico City, from July 2012 to June 2023.
Clinico-mycological characteristics and outcomes of rare yeast infections.
Indian J Med Microbiol
August 2024
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, 110029, India. Electronic address:
Article Synopsis
A review of the epidemiology of invasive fungal infections in Asian patients with hematological malignancies (2011-2021).
Epidemiol Rev
September 2024
Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Article Synopsis
- The rise of invasive fungal infections (IFIs) is notably higher in patients with hematological malignancies due to their weakened immune systems.
- Key risk factors for developing IFIs include older age, use of immunosuppressive drugs, low white blood cell counts (neutropenia), and the presence of catheters.
- The study highlights a lack of epidemiological data on IFIs in Asian patients and explores diagnostic and management challenges over the past decade (2011-2021).
AWMF mold guideline "Medical clinical diagnostics for indoor mold exposure" - Update 2023 AWMF Register No. 161/001.
Allergol Select
May 2024
Laboratory Dr. Wisplinghoff.
Article Synopsis
- This text lacks any provided content or specific information.
- Without details, it is impossible to summarize or draw key points.
- For a meaningful synopsis, additional context or a defined topic is needed.
Unveiling Trichosporon austroamericanum sp. nov.: A Novel Emerging Opportunistic Basidiomycetous Yeast Species.
Mycopathologia
May 2024
Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute (WI-KNAW), Uppsalalaan 8, 3584CT, Utrecht, The Netherlands.
Article Synopsis
- - A new species of yeast called Trichosporon austroamericanum sp. nov. was identified during an epidemiological survey of a kidney transplant recipient from Brazil, based on a urine sample.
- - The strain was characterized using molecular techniques, specifically the intergenic spacer (IGS1) ribosomal DNA locus, revealing its close relation to Trichosporon inkin but highlighting its uniqueness.
- - T. austroamericanum can be differentiated from other related Trichosporon species through distinct morphological, physiological, and phylogenetic traits.
co-infection with in a renal transplant patient.
IDCases
April 2024
Department of Laboratory Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
is considered an opportunistic pathogen, capable of causing superficial infections in humans and invasive deep-seated infections in immunocompromised hosts. can cause life-threatening pneumonia in immunosuppressed patients. Both and are highly lethal in immunocompromised individuals.
View Article and Find Full Text PDFArticle Synopsis
- - Invasive fungal infections are a major health risk for immunocompromised patients, leading to high rates of illness and death.
- - The most common fungal pathogens in Europe are Aspergillus and Candida, but other types like Mucorales are also becoming more frequent.
- - Diagnosing these infections is difficult and relies on a mix of imaging, clinical symptoms, fungal cultures, microscopy, and various tests to detect antibodies or genetic material.