3,269 results match your criteria: "Trauma Lower Genitourinary"

Traumatic ureteral injury: an initial outcome and experience.

Ther Adv Urol

December 2024

Department of Urology, Peking University First Hospital, 8 Xishiku Street, Xicheng, Beijing 100034, China.

Traumatic ureteral injury is a rare and challenging condition of the urinary system. To summarize the clinical features of patients with traumatic ureteral injury and examine the literature on traumatic ureteral injuries from the past 20 years. The clinical data of 30 patients with traumatic ureteral injury in Peking University First Hospital, Beijing Jiangong Hospital, as well as Emergency General Hospital from August 2015 to August 2023 were retrospectively collected.

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Spontaneous transvaginal small bowel evisceration, without recent trauma or surgery, is extremely rare. Complications include bowel obstruction, perforation, gangrene, septicaemia and death, requiring urgent surgical intervention. We report a case of a woman in her late 60s, who presented with 70-75 cm of small intestine eviscerated through the vagina, alongside a long history of uterine and rectal prolapse.

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Background: This study aims to investigate the impact of combining crush fluid resuscitation with gelsolin treatment on renal function in a rat model of crush syndrome.

Methods: Twenty-four adult female Wistar albino rats were randomly assigned to one of three groups for crush syndrome treat-ment: Control (C) group, gelsolin + crush fluid (gel) group, and crush fluid only (CF) group, each containing eight rats. Sedated rats underwent unilateral hind limb compression of 2 kg using a compression device, maintained for five hours.

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Background: This study reports our seven-year experience of one-year follow-up results after scrotal and testicular trauma, classified according to the Gülhane Grading System (GGS). We provide detailed hormonal analyses, ultrasound (US) evaluations, and spermiogram results. There are no previous studies that focus on all these detailed topics in relation to a grading system.

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Effect of maternal heat stress at different stages of pregnancy on the reproductive performance and antral follicle count of the progeny of Holstein cows.

Anim Reprod Sci

January 2025

Faculty of Animal Science and Veterinary Medicine, UFLA, Lavras, MG 37200-900, Brazil; Department of Veterinary Medicine, UFJF, Juiz de Fora, MG 36036-900, Brazil.

Article Synopsis
  • The study aimed to investigate how maternal heat stress during pregnancy affects the reproductive capabilities and follicle count of dairy calves.
  • Conducted in southeastern Brazil, it analyzed data from Holstein cows exposed to heat stress in different trimesters, comparing them to non-exposed cows.
  • Results showed that heat stress led to lower reproductive performance, longer calving intervals, and reduced antral follicle counts in their calves, indicating adverse effects on future fertility.
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[Fire needle therapy combined with bladder function training for neurogenic bladder caused by spinal cord injury: a randomized controlled trial].

Zhongguo Zhen Jiu

December 2024

Inpatient Department of Acupuncture-Moxibustion and Tuina, 3Second Inpatient Department of Endocrinology, Tangshan TCM Hospital, Tangshan 063000, Hebei Province, China.

Objective: To observe the clinical effect and safety of fire needle therapy combined with bladder function training on neurogenic bladder (NB) caused by spinal cord injury.

Methods: A total of 60 patients with NB caused by spinal cord injury were randomly divided into an observation group and a control group , with 30 cases in each group. On the basis of conventional treatment with western medicine, the bladder function training was adopted in the control group, once a day and for 4 weeks.

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Introduction: Morphological changes in the prostatic urethra and bladder cavity resulting from Aquablation treatment are still unknown. This study aims to assess the safety and efficacy of Aquablation within one-year post-surgery, focusing on both functional and endoscopic outcomes.

Methods: Prospective enrollment of patients undergoing Aquablation (10/2018-04/2023) included those with baseline International Prostate Symptom Score (IPSS) ≥ 10, prostate volume from 40 to 80 mL, and Qmax ≤ 12 mL/s.

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Article Synopsis
  • Sitafloxacin is a 4th generation fluoroquinolone antibiotic effective against both Gram-negative and Gram-positive bacteria, primarily used in Japan to treat infections like pneumonia and UTIs.
  • It has a low minimum inhibitory concentration (MIC) for various bacteria and is effective against anaerobes, intracellular bacteria, and biofilms, showing promise in treating implant-related infections.
  • The review focuses on sitafloxacin's mechanisms, activity, resistance profile, and potential for future clinical use, suggesting further evaluation in biofilm-related infections.
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Article Synopsis
  • - The study compares two decellularization methods (enzyme-detergent and detergent-detergent) to see how they affect the structure and mechanics of human urethral tissue, using samples from 18 individuals.
  • - Both methods successfully removed cellular content while maintaining essential extracellular matrix components like collagen and elastic fibers, indicating they preserved the tissue's structural integrity.
  • - Biomechanical tests showed that the detergent-detergent method resulted in lower stress levels compared to native tissues, and both methods had reduced elasticity, but none were toxic to stem cells, suggesting they are viable for tissue engineering and biobanking.
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Background: Renal hypoxia and ischemia significantly contribute to chronic kidney disease (CKD) progression, underscoring the need for noninvasive quantitative assessments. This study employs blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) and arterial spin labeling (ASL) MRI to comprehensively evaluate renal oxygenation and blood flow in CKD patients.

Methods: Forty-two CKD patients across stages 1-5 and ten healthy volunteers underwent simultaneous BOLD-MRI and ASL-MRI.

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Interstitial cystitis/bladder pain syndrome (IC/BPS) represents a chronic, aseptic inflammatory bladder condition with an unclear etiology and few therapeutic options. A composite barrier structure composed of the uroepithelium and glycosaminoglycan layer forms on the bladder's inner surface to block urine and other harmful substances. Dysfunction of this barrier may initiate the pathogenesis of IC/BPS.

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The presence of foreign bodies in the lower urinary tract has always been an interesting topic. From time to time, every urologist encounters such patients in their practice. A large number of such observations are described in the literature.

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Background: The other side of radiotherapy (RT), in addition to the cytotoxic effect, is the ability to modulate the immune system in terms of activation or suppression, also depending on the dose and fractionation delivered. This immune RT effect can be detected both locally in the irradiated tumor site and in the peripheral blood. The aim of this study was to assess the consequence of pelvic irradiation on peripheral immune cells and cytokine secretions in localized prostate cancer (PC) patients undergoing pelvic irradiation with a simultaneous moderately hypofractionated prostate/prostate bed boost by Volumetric Modulated Arc Therapy (VMAT).

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Lower uterine segment thickness to predict uterine rupture: a secondary analysis of PRISMA cluster randomized trial.

Am J Obstet Gynecol MFM

December 2024

Centre de Recherche du CHU de Québec-Université Laval, Québec, Canada (Bujold, Dubé, Girard, and Chaillet); Department of Obstetrics and Gynecology, Faculty of Medicine, Université Laval, Québec, Canada (Bujold and Chaillet).

Background: Third-trimester lower uterine segment thickness (LUST) is associated with uterine rupture during trial of labor after cesarean (TOLAC) but threshold values vary according to the approach used (lower values with vaginal ultrasound, higher values with abdominal ultrasound).

Objective: To estimate the optimal LUST cut-off value combining vaginal and abdominal ultrasound to predict uterine rupture during TOLAC.

Study Design: We performed a secondary analysis of PRISMA cluster randomized trial including women with a single previous cesarean who underwent ultrasound LUST measurement at 34-38 weeks using the thinnest measurement obtained by combining transvaginal and transabdominal measurements.

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Introduction And Clinical Importance: Inserting foreign bodies (FBs) into the lower genitourinary tract is an emergency and uncommon medical condition. The materials used for this purpose are batteries, telephone cables, wires and glass. This report highlights a rare case of urethrovesical FBs "hand sewing needles", emphasizing the limited literature on asymptomatic long-term retention and discussing removal strategies that include conservative care, endoscopic retrieval, and surgical intervention based on case complexity.

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Article Synopsis
  • The study assessed the feasibility and outcomes of I-LEVUR, a surgical technique for treating upper moiety ectopic ureter in patients with a duplex renal system, which avoids reimplanting the lower ureter.
  • Twelve patients, mostly young children, underwent the procedure with a mean surgical time of 127.5 minutes, and no major complications were reported post-surgery.
  • Results indicated improved urinary continence in all patients after an average follow-up of about 78.5 months, suggesting that I-LEVUR is a safe and effective option that preserves normal ureter function.
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Rationale: Complex vesicovaginal fistulas (VVFs) with large defects pose significant surgical challenges. Traditional repair methods often require extensive tissue separation and multilayer suturing, risking local blood supply and healing. This study introduces a novel modified transvaginal repair technique that simplifies the procedure while preserving tissue vascularity.

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  • The study investigates how COVID-19 affects bladder function in patients with benign prostate hyperplasia (BPH) by using sonography video urodynamic studies, a method not previously utilized for this purpose.
  • Results show that BPH patients with a history of COVID-19 have a significantly higher incidence of detrusor underactivity (DU), reduced bladder muscle contractility, and thicker bladder walls compared to those without COVID-19.
  • The findings suggest that COVID-19 may worsen bladder issues arising from existing conditions like BPH, indicating that DU could be a potential urodynamic marker of long-COVID.
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One potential advantage of single-port (SP) robotic surgery compared with multiport (MP) robotic surgery is improved cosmesis. The only studies in urology patients to suggest this finding did not assess differences based on incision site. Our study evaluated SP, MP, incision location, age, gender, and prior abdominal surgery as predictors of cosmesis and scar consciousness for reconstructive procedures.

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Introduction: Rhabdomyosarcoma is the most common neoplasm of skeletal myoblast-like cells in children aged 5-8 years. It typically occurs in the head, neck region, genitourinary tract, retroperitoneum, and extremities.

Case Presentation: An 8-year-old boy complained of a lump under his left eye that he had felt for the past 4 years.

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Article Synopsis
  • - Cancer is the second leading cause of death globally, and about 50% of patients receive radiation therapy, predominantly photon radiation, despite advancements in proton radiation therapy (PBT) that aims to minimize damage to healthy tissue.
  • - Proton therapy utilizes the Bragg peak property of protons to deliver targeted radiation with potentially lower toxicity compared to photon therapy, but patients may still experience proton-specific side effects.
  • - Reported toxicities from proton therapy include issues related to the brain, lungs, heart, gastrointestinal system, and genitourinary system; while similar to those from photon therapy, they generally occur less frequently.
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  • * A new electrical neuromodulation technique was developed, using stimulation of the major pelvic ganglion and pudendal nerve to promote bladder contractions and relaxation of the external urethral sphincter in SCI mice.
  • * The study's results indicate that this technique effectively improves voiding function and mimics natural urination patterns, showing potential for personalized treatments for individuals suffering from NLUTD due to SCI.
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  • * The condition can affect various mucosal areas, including the mouth and genitals, and is typically triggered by a hypersensitivity reaction to drugs like NSAIDs, antibiotics, and anticonvulsants.
  • * A case study is presented of a 79-year-old woman who developed TEN after taking clindamycin for a sacral ulcer, emphasizing the need for awareness and quick management of SJS/TEN after new medication use to enhance patient outcomes.
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Aim: Recently, substantial studies have been accumulated to indicate the important role of gut microbiota in diabetic kidney disease (DKD). The abnormal change of bacterial-derived products could imply specific injuries or play beneficial or harmful roles in DKD progression. In this study, we examined the presence and contribution of the Klebsiella oxytoca gene in the circulation of patients with DKD.

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  • Environmental heat stress negatively impacts reproductive efficiency in farm animals, specifically prepubertal Ossimi ram lambs exposed to severe heat conditions in this study.* -
  • The study assessed the effects of melatonin and nano melatonin treatment on various reproductive parameters, finding that both treatments improved testicular function and structure compared to a control group.* -
  • Results showed significant increases in testicular volume, echotexture, and antioxidant levels in the treated groups, although testosterone levels remained unchanged.*
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