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Association Between Plasma Concentration of Klotho Protein, Osteocalcin, Leptin, Adiponectin, and Bone Mineral Density in Patients with Chronic Kidney Disease.

Horm Metab Res

November 2018

Department of Nephrology, Transplantology and Internal Diseases Pomeranian Medical University, Szczecin, Poland.

Małgorzata Marchelek-Mysliwiec Magda Wisniewska Monika Nowosiad-Magda Krzysztof Safranow Ewa Kwiatkowska

Patients with early-stage chronic kidney disease (CKD) are susceptible to changes in metabolic processes. Partial loss of kidney function leads to homoeostatic disturbances in bone and fatty tissue. The aim of this study was to investigate the association between plasma concentrations of Klotho protein, FGF23, leptin, adiponectin, osteocalcin, and bone mineral density (BMD) in patients with CKD in the pre-dialysis period.

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