1 results match your criteria: "Translational Research Institute Queensland University of Technology (QUT) Brisbane QLD Australia.[Affiliation]"
Systematic review of antitumour efficacy and mechanism of metformin activity in prostate cancer models.
BJUI Compass
January 2023
Australian Prostate Cancer Research Centre-Queensland, Centre for Genomic and Personalised Health, School of Biomedical Sciences, Faculty of Health, Translational Research Institute Queensland University of Technology (QUT) Brisbane QLD Australia.
Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting. Despite multiple studies evaluating the mechanisms underpinning antitumour effects of metformin in PCa, to date, no reviews have compared these findings.
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