1 results match your criteria: "Translational Medicine Research Institute The Hospital for Sick Children Toronto Canada.[Affiliation]"
Background: Upon platelet activation, a subpopulation of procoagulant platelets is formed, characterized by the exposure of the anionic aminophospholipid phosphatidylserine (PS) on the surface membrane.
Objective: To evaluate procoagulant PS-exposing platelets by imaging flow cytometry.
Methods: Platelet ultrastructure was examined by transmission electron microscopy, and a comprehensive analysis of procoagulant platelets was performed using imaging flow cytometry; platelets were fluorescently labeled for the markers glycoprotein (GP)IX, activated integrin αIIbβ3, CD62P, and PS exposure.