1,235 results match your criteria: "Transient Global Amnesia"

Punctate hippocampal hyperintensity (PHH) on diffusion-weighted imaging (DWI) is a well-known observation in patients with transient global amnesia (TGA), which is characterized by acute self-limiting episodes of anterograde and retrograde amnesia. These lesions occur unilaterally or bilaterally in the CA1 regions of the hippocampus, which are crucial for memory processes. PHH on DWI is well-documented in TGA but rare in other conditions.

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Article Synopsis
  • Transient global amnesia (TGA) is a temporary memory condition often seen in older adults, marked by sudden memory loss that resolves within 24 hours while the person remains aware of their identity.
  • A case study of a woman in her 60s illustrates how her acute memory problems were initially mistaken for a stroke after taking migraine and sleep medications, but were later correctly identified as TGA.
  • This situation emphasizes the need to carefully distinguish TGA from other serious conditions to avoid unnecessary treatments and hospital costs, particularly since combining certain medications may increase the risk of TGA.
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Background: Choline was frequently reported to have some beneficial effects on memory function. However, the association of dietary choline with different types of amnesia is not well understood. The objective of this study was to examine the association between dietary intake of choline and transient global amnesia (TGA).

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Unlabelled: Transient global amnesia (TGA) is a rare, temporary, sudden-onset disturbance in anterograde episodic memory with unclear pathophysiology. Previous brain volumetric analysis in TGA patients showed varied results.

Objective: To explore brain morphometry, hypothesizing that patients with TGA exhibit structural alterations.

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Article Synopsis
  • The study investigates the link between transient global amnesia (TGA) and dietary intake of vitamin B12, aiming to understand how diet might influence this form of short-term memory loss.
  • Conducted with 258 individuals with TGA and 520 without in Sabzevar, Iran, researchers used a Food Frequency Questionnaire to assess vitamin B12 intake and employed logistic regression models for analysis.
  • Findings indicate that higher dietary intake of vitamin B12 is associated with a lower risk of TGA, suggesting that vitamin B12 deficiency could be a concern for those at risk; further research is recommended to explore this relationship.
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Choroid plexus volumes in patients with transient global amnesia: A retrospective study.

Medicine (Baltimore)

October 2024

Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.

Increased choroid plexus (ChP) volume is well known to be associated with glymphatic system dysfunction. This study aimed to investigate glymphatic system function in patients with transient global amnesia (TGA) compared to healthy controls through ChP volumes measurements. We retrospectively enrolled patients with TGA from our hospital, as well as healthy controls.

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Both transient epileptic amnesia (TEA) and transient global amnesia (TGA) are clinically characterized by temporary amnesic symptoms. TEA involves recurring amnesic episodes, while TGA typically manifests as a singular occurrence. TGA rarely occurs repeatedly, known as recurrent TGA (r-TGA), which complicates differentiation, and raises the possibility of overlap between two disorders.

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Article Synopsis
  • - The study investigated the presence of small vessel disease in patients with transient global amnesia (TGA) by using a new marker called peak width of skeletonized mean diffusivity (PSMD).
  • - Researchers compared PSMD levels between 75 newly diagnosed TGA patients and 65 healthy controls, finding that TGA patients had significantly higher PSMD values.
  • - The results suggest that PSMD could be a potential marker for detecting small vessel disease in neurological disorders, indicating that such diseases may be present in TGA patients even without common vascular risk factors.
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Article Synopsis
  • Transient global amnesia (TGA) is a short-term memory condition that can be confused with other serious issues like hippocampal infarction, which needs further treatment.
  • A case study involving a 60-year-old woman showed difficulty in diagnosing between TGA and hippocampal infarction for about a week after her sudden onset of amnesia.
  • MRI scans revealed important differences over time, highlighting the need for thin-slice MRI and follow-up imaging to accurately distinguish between these two conditions.
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Cognitive deficits and course of recovery in transient global amnesia: a systematic review.

J Neurol

October 2024

Department of Neurology, University Hospital of Larissa, Faculty of Medicine, University of Thessaly, Mezourlo Hill, 41100, Larissa, Greece.

Article Synopsis
  • - The study aimed to explore cognitive deficits during transient global amnesia (TGA) episodes, discovering that impairments extend beyond just episodic memory.
  • - Researchers reviewed 1302 articles, ultimately including 17 in their analysis, and found that TGA patients experience significant issues with spatiotemporal awareness, anterograde amnesia, and working memory during acute episodes.
  • - Although many cognitive functions remain normal, recovery typically starts with spatiotemporal orientation, followed by working and semantic memory retrieval, while episodic memory issues may last longer, with subtle memory deficits possible even after 24 hours.
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  • * Researchers conducted a case-control study with 258 individuals with TGA and 520 without, using a food frequency questionnaire to assess fat intake.
  • * Findings indicate that higher intake of alpha-linolenic acid (a type of omega-3) is linked to a lower risk of TGA, while higher intake of n-6 fatty acids is associated with an increased risk, even after accounting for other factors.
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Article Synopsis
  • A 48-year-old patient had sudden memory loss (amnesia) 10 weeks after brain surgery for epilepsy.
  • Doctors thought it might be related to the epilepsy, but tests showed no signs of seizures during the memory loss episode.
  • This situation shows why it's important for doctors to recognize different types of memory problems after epilepsy surgery so patients don't get treated unnecessarily.
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Background And Objective: Atorvastatin is a drug widely used to prevent cardiovascular and cerebrovascular diseases. Current observational studies suggest that atorvastatin may be associated with cognitive dysfunction (especially memory loss). However, some studies have suggested that dyslipidemia may be an important factor in cognitive dysfunction.

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Increased risk of epilepsy after transient global amnesia: A population-based study in South Korea.

Clin Neurol Neurosurg

August 2024

Data Science Team, Hanmi Pharm. Co., Ltd., Seoul, South Korea.

Article Synopsis
  • The study examined the risk of developing epilepsy following an episode of transient global amnesia (TGA) using data from the Korean National Health Insurance Service from 2002 to 2020.
  • Researchers found that patients with TGA had a significantly higher rate of epilepsy compared to those without TGA, with an adjusted hazard ratio indicating a 46% higher risk.
  • Factors such as age, sex, hypertension, diabetes, mental health conditions, and socioeconomic status were identified as significant contributors to the likelihood of developing epilepsy in TGA patients.
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A Dive Into Oblivion: A Case of Transient Global Amnesia.

Cureus

May 2024

Department of Critical Care Medicine, Unidade Local de Saúde do Litoral Alentejano, EPE, Santiago do Cacém, PRT.

Article Synopsis
  • Transient global amnesia (TGA) is a rare neurological condition characterized by a sudden, temporary loss of memory, both for current events and past experiences.
  • A case study of a 58-year-old woman highlighted TGA, as she experienced sudden memory loss and disorientation after an ocean dive, with all medical tests returning normal results.
  • After close monitoring in the emergency department, she gradually recovered her ability to form new memories and was discharged with no lasting symptoms, with a need for further research to understand TGA's causes and risk factors.
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Article Synopsis
  • A case of transient global amnesia occurred after administering a non-ionic iodinated contrast agent for an abdominal CT scan.
  • Follow-up MRI scans showed signs of hippocampal microinfarction and temporary cerebral vasospasm.
  • This is the first documented case highlighting the risk of arterial vasospasm related to intravenous iodinated contrast, emphasizing the need for caution among medical professionals.
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Vertebral artery hypoplasia and hemodynamic impairment in transient global amnesia: a case control study.

Front Neurol

May 2024

Neurologie und Stroke Unit, Katholisches Klinikum Koblenz-Montabaur, Koblenz, Germany.

Introduction: The aetiology of transient global amnesia (TGA) is still a matter of debate. Besides ischemia of the mesial temporal lobe including the hippocampus, migraine-like mechanisms, epileptic seizures affecting mnestic structures, or venous congestion in the (para) hippocampal area due to jugular vein insufficiency have been discussed. We assessed the diameters of the intracranial arteries of TGA patients compared to controls to identify differences that support the hypothesis of reduced hippocampal perfusion as a pivotal factor in the pathophysiology of TGA.

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Article Synopsis
  • - Transient global amnesia (TGA) is a temporary condition primarily affecting older adults, causing short-term memory loss for new information, lasting 30 seconds to 3 minutes, while other cognitive functions remain intact.
  • - Recent data suggests TGA occurs more frequently than previously thought, with about 15 cases per 100,000 people annually, and episodes typically resolve within 24 hours, but 10% may experience future episodes.
  • - MRI scans often reveal small lesions in the hippocampus in TGA patients, but the precise causes and mechanisms are still unclear; potential triggers include physical exertion and anxiety, and reassurance for concerned relatives is part of managing TGA.
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Background And Purpose: This study aimed to evaluate the brain magnetic resonance imaging (MRI) of patients with acute transient global amnesia (TGA) using volumetric analysis to verify whether the brains of TGA patients have pre-existing structural abnormalities.

Methods: We evaluated the brain MRI data from 87 TGA patients and 20 age- and sex-matched control subjects. We included brain MRIs obtained from TGA patients within 72 hours of symptom onset to verify the pre-existence of structural change.

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Takotsubo syndrome and transient global amnesia can occur simultaneously, not only in the context of acute but also long-standing emotional stress. Probably, hypothyroidism and migraine make the patient more susceptible to both of these disorders.

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Objective: Cerebral Small Vessel Disease (CSVD) has not been systematically studied in patients with Transient Global Amnesia (TGA). We aimed to investigate the CSVD burden in patients with TGA and its relationship with TGA recurrence.

Methods: We retrospectively examined 69 patients diagnosed with TGA in a single center between January 2015 and November 2023.

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