28 results match your criteria: "Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region[Affiliation]"
Association of human leukocyte antigen DP/DQ gene polymorphisms with chronic hepatitis B in Chinese Han and Uygur populations.
Infect Genet Evol
September 2016
Centre of Clinical Laboratory, the Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China. Electronic address:
Several genome-wide association studies (GWAS) have shown that human leukocyte antigen (HLA) DP/DQ gene polymorphisms are associated with susceptibility to chronic hepatitis B virus (HBV) infection. We clarified the roles of the HLA-DP/DQ gene in HBV infection in different nationalities. Three single nucleotide polymorphisms (SNPs) in HLA-DP (rs9277471, rs9277535 and rs9277542) and the SNP rs9272346 in HLA-DQ were studied.
View Article and Find Full Text PDFVariants in the Atherogenic ALOX5AP, THBD, and KNG1 Genes Potentiate the Risk of Ischemic Stroke via a Genetic Main Effect and Epistatic Interactions in a Chinese Population.
J Stroke Cerebrovasc Dis
September 2015
Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, China.
Background: Ischemic stroke (IS) is a multifactorial disease that displays a strong genetic predisposition. However, the genetic architecture of IS has yet to be fully elucidated. It was hypothesized that epistasis between genes in multiple atherothrombotic pathways may play a vital role in determining the susceptibility to IS.
View Article and Find Full Text PDFGene polymorphism of rs556621 but Not rs11984041 is associated with the risk of large artery atherosclerotic stroke in a Xinjiang Uyghur population.
J Stroke Cerebrovasc Dis
December 2015
Department of Neurology, the Third Xiangya Hospital, Central South University, Changsha, China. Electronic address:
Article Synopsis
- Stroke is a leading cause of death and disability in adults, and recent studies have linked specific genetic variants (rs556621 and rs11984041) to large artery atherosclerosis (LAA).
- Researchers examined these variants in a study of 733 LAA stroke patients from the Xinjiang Uyghur region of China, comparing them to a control group of 725 individuals.
- The findings showed that the rs556621 variant was significantly associated with LAA in the Uyghur population but not in the Han Chinese, while no notable differences were found for the rs11984041 variant in either group.