5,883 results match your criteria: "Tracheal Intubation Laryngeal Mask Airways"

Background: Ciprofol, a novel intravenous anesthetic, exhibits similar sedation mechanisms and pharmacokinetic properties to propofol. However, ciprofol demonstrates greater potency and is associated with reduced injection pain compared to propofol. Given the varying sensitivities to anesthetic agents across different age groups, this study aims to determine the median effective dose (ED) of ciprofol required to suppress the laryngeal mask airway (LMA) insertion response in both young and older adult patients, as well as to assess its potential adverse reactions.

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Introduction: The effectiveness of supraglottic airway devices (SGDs) as a strategy for blind endotracheal intubation (ETI) was compared in this study.

Methods: A systematic review of clinical trials (CTs) involving SGDs for blind ETI in patients under general anesthesia or simulation manikins, was conducted. CTs that used SGDs for fiberoptic-guided ETI and those conducted in children were excluded.

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Article Synopsis
  • The study aimed to identify anesthetic agents that reduce negative outcomes during laryngeal mask airway (LMA) insertion in adult patients receiving general anesthesia.
  • A network meta-analysis of 53 randomized controlled trials involving 4695 patients found that the combination of propofol and dexmedetomidine was most effective in minimizing adverse events during the procedure.
  • Overall, all anesthetic combinations, except for those involving thiopental, were better than propofol alone in reducing adverse outcomes related to apnea, insertion failure, and inadequate anesthesia depth.
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Study Objective: Second-generation laryngeal mask airways are equipped with an additional lumen for a gastric tube, with the intention to reduce the risk of aspiration by draining gastric content. However, the effect of an inserted gastric tube through the gastric channel on gastric insufflation, a substantial part of the pathomechanism of aspiration, during positive-pressure ventilation is not clear. We hypothesized, that an inserted gastric tube increases the risk of gastric insufflation.

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Background: Over the last two decades, significant research interest has led to the development of a wide variety of supraglottic airways (SGAs) for anaesthesia providers to choose from.

Methods: In this network meta-analysis, we analysed 111 studies, enrolling 12 045 patients undergoing airway management with 29 SGAs. We targeted outcomes that contribute to clinicians' choice of one SGA over another.

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Comparison of the clinical performance of the Ambu®AuraGain™ laryngeal mask in children undergoing surgery in the supine and prone position - A prospective, non-inferiority clinical trial.

J Clin Anesth

December 2024

Department of Anesthesiology and Pain Medicine, Severance Hospital, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodamungu, Seoul 03722, Republic of Korea. Electronic address:

Article Synopsis
  • This study evaluated the effectiveness of the Ambu®AuraGain™, a second-generation supraglottic airway (SGA), in children undergoing surgery in both prone and supine positions.
  • The research involved 126 children aged 2-12 years, measuring oropharyngeal leak pressure (OLP) after positioning and noting any airway-related issues.
  • Results showed that OLP in the prone position was not inferior to the supine position, although more airway maneuvers were needed for the prone position, suggesting it may be slightly more challenging.
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Comparison of the ED50 of Ciprofol Combined With or Without Fentanyl for Laryngeal Mask Airway Insertion in Children: A Prospective, Randomized, Open-Label, Dose-Response Trial.

Drug Des Devel Ther

October 2024

Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Key Laboratory of Pediatric Anesthesiology of Ministry of Education, Wenzhou, Zhejiang Province, People's Republic of China.

Article Synopsis
  • The study investigated how different doses of fentanyl affect the required dose of ciprofol for smooth insertion of a laryngeal mask airway (LMA) in healthy preschool children undergoing surgery.
  • 90 patients were divided into three groups, receiving either ciprofol alone or ciprofol with varying doses of fentanyl, with the main outcome being the effective dose of ciprofol needed for LMA insertion.
  • Results showed that higher doses of fentanyl significantly reduced the amount of ciprofol needed and decreased the time to loss of consciousness, with minimal side effects reported among the groups.
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Upper airway resistance during use of a laryngeal mask airway is flow-dependent and dominated by the laryngeal resistance.

Sci Rep

October 2024

Department of Anesthesiology and Critical Care, Medical Center, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

Article Synopsis
  • * Researchers measured the pressure-flow relationships using different sizes of LMAs and varying vocal cord angles to understand their resistive behavior more clearly.
  • * Findings indicate that upper airway resistance is a combined, nonlinear factor that primarily depends on the angle of the vocal cords, which accounts for 59-98% of the total resistance in adults when using an LMA.
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Article Synopsis
  • The study compares two methods for inserting a laryngeal mask airway (LMA): the standard technique and a technique using a 30° curved tongue depressor.
  • Involving 154 patients, the results showed a significantly higher first-attempt success rate for the tongue depressor-aided method (97.40%) compared to the standard method (88.31%).
  • Additionally, the tongue depressor technique reduced the incidence of sore throat symptoms post-insertion, suggesting it as a superior option for LMA insertion.
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Article Synopsis
  • The study investigates how positioning the endotracheal tube (ET) at the glottis through a laryngeal mask airway (LMA) can reduce ventilation issues caused by glottic contraction during surgery.
  • In a randomized trial, patients were divided into two groups: one using only the LMA and the other combining the LMA with the ET, showing significantly lower leakage rates in the latter group.
  • Results indicated that while the combination method reduced LMA leakage, it also maintained stable blood pressure and heart rate, with no significant increase in postoperative complications.
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Article Synopsis
  • In emergency situations, airway management is crucial, with endotracheal intubation being the standard method for unconscious patients, allowing for effective ventilation and removal of secretions.
  • Supraglottic airways, such as the intubating laryngeal mask airway (ILMA), offer advantages like quicker insertion and less reliance on paralysis, making them useful as a backup or in difficult scenarios.
  • This study aims to test the ILMA's effectiveness in prehospital settings, particularly when access around the patient's head is limited, and evaluates a new handle design for easier insertion from any angle.
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Article Synopsis
  • The study aimed to evaluate the placement effectiveness of the V-gel Advanced (V-gel-A) in cats during controlled ventilation using CT scans, comparing it with endotracheal tube placement.
  • Twenty healthy cats underwent CT scans at different stages: baseline, after V-gel-A placement, after 5 minutes of controlled mechanical ventilation, and after endotracheal tube insertion, assessing position and gas distribution.
  • Results showed that the V-gel-A was mostly well-positioned, with a high success rate at first attempt; however, it sometimes failed to completely occlude the esophagus, potentially affecting tracheal selectivity.
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Airway management for patients with tracheal stenosis and severe scar contracture of the face and neck via bronchoscopy: a case report.

J Cardiothorac Surg

September 2024

Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.

Article Synopsis
  • Both anaesthesiologists and surgeons face significant challenges when dealing with airway stenosis and scars in the face and neck, as exemplified by a case of a 38-year-old woman with severe airway constriction due to burns.
  • The patient presented with a very difficult airway (limited mouth opening and severe tracheal stenosis) and had a trachea only 5.5 mm wide, making standard procedures problematic.
  • After unsuccessful attempts to insert a laryngeal mask, a custom tracheal tube was successfully placed using a fiberoptic bronchoscope, allowing for the patient's transfer to the ICU post-operation.
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Article Synopsis
  • * Results showed that the LMA blockbuster had a significantly higher success rate (91.4%) for blind intubation compared to the Air-Q ILA (55.7%).
  • * Despite similar numbers of attempts and insertion times for both devices, the LMA blockbuster proved to be more effective, particularly when enhanced with specialized tubes and techniques.
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Innovative (and Safe) Techniques With Supraglottic Airways.

Int Anesthesiol Clin

October 2024

Department of Anesthesiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.

Article Synopsis
  • Supraglottic airways serve as alternatives to traditional facemask ventilation and endotracheal intubation, playing a crucial role in airway management since the late 1980s.
  • The chapter discusses key aspects of using these devices and offers an update on their current clinical practices, highlighting safe management techniques.
  • Advancements in supraglottic airway technology have improved their effectiveness in addressing modern airway challenges, benefiting both patients and medical practitioners.
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Article Synopsis
  • * A total of 141 elderly patients were divided into three groups receiving different anesthesia methods: one group preserving spontaneous breathing, and two groups using mechanical ventilation with either laryngeal mask airway or tracheal intubation.
  • * Results showed that the group with spontaneous breathing (Group A) had significantly faster onset times, quicker recovery, lower sedation and pain scores, and better mental function post-anesthesia compared to the other two groups.
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Article Synopsis
  • The study investigated the effective doses (ED50 and ED95) of remimazolam for laryngeal mask airway insertion in pediatric patients undergoing strabismus correction surgery.
  • It included 32 children aged 3-12 and employed a precise dosage method to determine the necessary amounts for effective sedation.
  • Results showed that the ED50 was 0.300 mg/kg and ED95 was 0.369 mg/kg, with patients maintaining stable vital signs throughout the procedure, indicating safety and reliability for clinical use.
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Article Synopsis
  • This study compares the use of supraglottic airway devices (SAD) and endotracheal tubes (ETT) for general anesthesia in former preterm infants undergoing herniorrhaphy.
  • The research found that infants using SAD experienced significantly fewer cases of intraoperative desaturation compared to those using ETT (21.1% vs. 73.7%).
  • Overall, while SAD showed better outcomes for intraoperative desaturation, the rates of other respiratory complications were similar between both groups, and all infants were successfully extubated after surgery.
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A new video laryngoscope combined with flexible laryngeal mask insertion: A prospective randomized study.

J Clin Anesth

November 2024

Affiliated Chifeng Clinical Medical College of Inner Mongolia Medical University, Chifeng, Inner Mongolia, China; Department of Anesthesiology, Chifeng Municipal Hospital, Chifeng, Inner Mongolia, China. Electronic address:

Article Synopsis
  • The study evaluated the effectiveness of an improved video laryngoscope (VLS) for inserting a flexible laryngeal mask airway (F-LMA) compared to the standard blind insertion technique.
  • Results showed a significantly higher first-attempt success rate (99% for VLS vs. 86% for standard) and better oropharyngeal leakage pressure with the VLS method.
  • The new VLS technique required less adjustment and reinsertion, offering a safer and more efficient airway management option without increasing the risk of complications.
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Article Synopsis
  • The study compared the Air-Q Self Pressurized Airway Device with Blocker (SP Blocker) to the Proseal Laryngeal Mask Airway (PLMA) for positive pressure ventilation in adult female patients undergoing elective surgeries.
  • Significant results showed that the SP Blocker had better performance on key metrics like oropharyngeal leak pressure (OLP), lower peak inspiratory pressure (PIP), and improved tidal volumes compared to the PLMA.
  • Additionally, the SP Blocker allowed for faster insertion times, indicating it may be a more effective option for airway management during surgeries.
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Article Synopsis
  • This study looked at whether a special way to position obese patients (called the ramped position) makes it easier and faster to put in a breathing device during surgery.
  • The researchers found that it took less time to insert the device in the ramped position compared to another position called the sniffing position, and it was easier for the doctors too.
  • Overall, the ramped position is a better choice for helping patients breathe during surgery without causing extra problems.
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Article Synopsis
  • - The study investigates the use of advanced endotracheal intubation (ETI) techniques in critically ill children, as direct laryngoscopy (DL) is commonly used but not always effective.
  • - Data was collected from the National Emergency Airway Registry for Children (NEAR4KIDS) over a three-year period, excluding cases that only used DL.
  • - Advanced ETI techniques showed a 91.1% overall success rate, with video laryngoscopy being the most common method, indicating that multiple medical disciplines, including pediatric critical care and anesthesia, are involved in this process.
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