409 results match your criteria: "Toyota Technological Institute[Affiliation]"

Because large brains are energetically expensive, they are associated with metabolic traits that facilitate energy availability across vertebrates. However, the biological underpinnings driving these traits are not known. Given its role in regulating host metabolism in disease studies, we hypothesized that the gut microbiome contributes to variation in normal cross-vertebrate species differences in metabolism, including those associated with the brain's energetic requirements.

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Rare-earth-transition-metal (RE-TM) ferrimagnets are excellent materials for spin encode/decode operations via spin transport in nonmagnetic regions. This superior performance stems from two key factors. First, the antiferromagnetic coupling between RE4f and TM3d sublattices reduces both the spin-transfer-torque switching time and inter-device magnetic-coupling.

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Studies on the ion-layer formation of imidazolium-based ionic liquids have extensively explored how to improve in-depth knowledge of electrical double-layer (EDL) properties. In this computational study, 1-alkyl-methylimidazolium bis(trifluoromethylsulfonyl)imide ([Cmim][NTf]), namely, [Cmim][NTf] and [Cmim][NTf], inside a simulated supercapacitor were investigated to expose an symmetric alkyl chain effect. Molecular dynamic simulations of a supercapacitor model with graphite electrodes were conducted.

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The signature feature of the 'strange metal' state of high-T cuprates-its linear-in-temperature resistivity-has a coefficient α that correlates with T, as expected were α derived from scattering off the same bosonic fluctuations that mediate pairing. Recently, an anomalous linear-in-field magnetoresistance (=γH) has also been observed, but only over a narrow doping range, leaving its relation to the strange metal state and to the superconductivity unclear. Here, we report in-plane magnetoresistance measurements on three hole-doped cuprate families spanning a wide range of temperatures, magnetic field strengths and doping.

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We investigated the thermoelectric and thermal behavior of Fe-V-W-Al-based thin films prepared using the radio frequency magnetron sputtering technique at different oxygen pressures (0.1-1.0 × 10 Pa) and on different substrates (n, p, and undoped Si).

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WO Nanofibers Functionalized with Graphene as a Selective Sensing of NO Gas at Room Temperature.

ACS Appl Mater Interfaces

September 2024

Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Indore, Simrol, Khandwa Road, Indore 453552, India.

Recent trends in two-dimensional (2D) graphene have demonstrated significant potential for gas-sensing applications with significantly enhanced sensitivity even at room temperature. Herein, this study presents fabrication of distinctive gas sensor based on one-dimensional (1D) WO nanofibers decorated 2D graphene, specifically coated on copper (Cu)-based interdigitated electrodes formed by DC sputtering, which can selectively detect NO gas at room temperature. The sensor device fabricated using WO/Gr1.

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Autoimmune diseases such as systemic lupus erythematosus (SLE) display a strong female bias. Although sex hormones have been associated with protecting males from autoimmunity, the molecular mechanisms are incompletely understood. Here we report that androgen receptor (AR) expressed in T cells regulates genes involved in T cell activation directly, or indirectly via controlling other transcription factors.

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Isotype-aware inference of B cell clonal lineage trees from single-cell sequencing data.

Cell Genom

September 2024

Toyota Technological Institute at Chicago, Chicago, IL 60637, USA; Department of Pathology, University of Chicago, Chicago, IL 60637, USA; Chan Zuckerberg Biohub Chicago, Chicago, IL 60642, USA. Electronic address:

Article Synopsis
  • Single-cell RNA sequencing (scRNA-seq) allows in-depth analysis of B cell evolution during immune responses, highlighting processes like somatic hypermutation (SHM) and class switch recombination (CSR).
  • The newly introduced TRIBAL algorithm focuses on accurately reconstructing B cell evolutionary histories by considering both SHM and CSR, addressing limitations of prior phylogenetic methods.
  • Simulations and real-world applications show TRIBAL outperforms existing approaches, offering more accurate lineage trees and insights into B cell responses, which can enhance vaccine development and therapeutic antibody identification.
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Article Synopsis
  • The sheath-in-sheath technique involves using a 15Fr cryoballoon delivery sheath inside a larger 16Fr sheath to assist in medical procedures.
  • This method is particularly effective for accessing complex iliac veins during cryoballoon ablation, a treatment for atrial fibrillation.
  • It ensures safe delivery of the cryoballoon while maintaining the device's performance and avoiding any complications.
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A Heat Flux Sensor (HFS) facilitates the visualization of heat flow, unlike a temperature sensor, and is anticipated to be a key technology in managing waste heat. Recently, an HFS utilizing the Anomalous Nernst Effect (ANE) has been proposed garnering significant interest in enhancing the transverse thermopower. However, ideal materials for HFS not only require a large transverse thermopower but also meet several criteria including low thermal conductivity and a bipolar nature of the transverse thermopower, especially a negative transverse thermopower.

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Hexagonal boron nitride (hBN) has a property similar to that of graphene, and it has become one of the most popular materials due to its flexible physical and chemical properties for a variety of applications, especially in nanoelectronics. Enhanced properties of hBN-based heterostructures are crucial for future electronic devices. In this work, a sheet-like hBN crystal was synthesized and transferred onto SiO/Si substrate and reduced graphene oxide (RGO)/SiO/Si substrate.

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A intermediate multidomain state and large crystallographic tilting of 1.78° for the (hh0) planes of a (001)-oriented single-domain Mn-doped BiFeO (BFMO) thin film were found when an electric field was applied along the [110] direction. The anomalous crystallographic tilting was caused by ferroelastic domain switching of the 109° domain switching.

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The newly-proposed tandem approach, Wire ThRoUgh Snare Twice (Wire TRUST) is effective for grasping a lead with inaccessible ends. This case report shows that Wire TRUST can also enable successful extraction of a left ventricular lead by iteratively grasping and repositioning to the distal portion of the lead.

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Momentum-dependent scaling exponents of nodal self-energies measured in strange metal cuprates and modelled using semi-holography.

Nat Commun

May 2024

Van der Waals - Zeeman Institute, Institute of Physics, University of Amsterdam, Sciencepark 904, 1098 XH, Amsterdam, The Netherlands.

The anomalous strange metal phase found in high-T cuprates does not follow the conventional condensed-matter principles enshrined in the Fermi liquid and presents a great challenge for theory. Highly precise experimental determination of the electronic self-energy can provide a test bed for theoretical models of strange metals, and angle-resolved photoemission can provide this as a function of frequency, momentum, temperature and doping. Here we show that constant energy cuts through the nodal spectral function in (Pb,Bi)SrLaCuO have a non-Lorentzian lineshape, consistent with a self-energy that is k dependent.

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Blood flow to the active muscles and arterial blood pressure (ABP) increase during dynamic exercise, whereas blood flow to inactive organs (e.g., splanchnic organs and inactive limbs) declines.

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Commensal microbes have the capacity to affect development and severity of autoimmune diseases. Germ-free (GF) animals have proven to be a fine tool to obtain definitive answers to the queries about the microbial role in these diseases. Moreover, GF and gnotobiotic animals can be used to dissect the complex symptoms and determine which are regulated (enhanced or attenuated) by microbes.

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Predictable Synthesis of 3D Polymer Networks Using Crystal Component-Linking.

Macromol Rapid Commun

July 2024

Department of Chemistry, Faculty of Science, Hokkaido University, Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan.

Controlled synthesis of 3D polymer networks presents a significant challenge because of the complexity of the polymerization reaction in solution. In this study, a polymerization system that facilitates the prediction of a polymer network structure via percolation simulations is realized. The most significant difference between general percolation simulations and experimental polymerization systems is the mobility of the molecules during the reaction.

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Single-sequence protein structure prediction by integrating protein language models.

Proc Natl Acad Sci U S A

March 2024

MoleculeMind Ltd., Beijing 100084, China.

Protein structure prediction has been greatly improved by deep learning in the past few years. However, the most successful methods rely on multiple sequence alignment (MSA) of the sequence homologs of the protein under prediction. In nature, a protein folds in the absence of its sequence homologs and thus, a MSA-free structure prediction method is desired.

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The purpose of this study was to clarify sex differences in the inhibition of sympathetic vasomotor outflow which is caused by the loading of cardiopulmonary baroreceptors. Ten young males and ten age-matched females participated. The participants underwent a passive leg raising (PLR) test wherein they were positioned supine (baseline, 0º), and their lower limbs were lifted passively at 10º, 20º, 30º, and 40º.

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