3,158 results match your criteria: "Toxocariasis"

Pattern of Uveitis in Northern Vietnam.

Ocul Immunol Inflamm

December 2024

Department of Ophthalmology, Hanoi Medical University, Hanoi, Vietnam.

Purpose: To characterize the spectrum of uveitis in patients visiting three tertiary hospitals in Hanoi, Vietnam.

Methods: This study collected prospective and multicenter data from patients diagnosed with uveitis at three tertiary hospitals in Hanoi City, Vietnam, between January 2022 and January 2024. Data on age, sex, clinical and laboratory findings, and etiology were collected.

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Toxocariasis is a common zoonotic parasitic disease, primarily caused by the larvae of or . Humans become infected through accidental ingestion of infective eggs in soil contaminated with feces of infected animals, or by consuming undercooked meat from paratenic hosts harboring larvae. This cross-sectional study aimed to evaluate the seroprevalence of spp.

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Article Synopsis
  • Toxocara canis and Toxocara cati are parasitic worms found globally, particularly posing risks to children through their eggs in the environment, highlighting the need for effective diagnostic methods for detection.
  • This study compared different detection techniques including a new sequential sieving protocol and a high-throughput qPCR method, evaluating their efficiency on cat and dog faecal samples.
  • Results indicated that the new sieving method was superior in sensitivity for egg detection, while mechanical lysis of DNA samples outperformed enzymatic lysis, and both DNA detection and microscopy methods showed comparable results with newer techniques being cost-effective.
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is one of the deadliest parasite of buffalo calves in Bangladesh. This study was conducted to explore genetic variability within and among the populations in buffalo calves of Bangladesh. Genomic DNA was extracted, and gene were amplified and sequenced.

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Proteomics analysis reveals the differential protein expression of female and male adult Toxocara canis using Orbitrap Astral analyzer.

Infect Dis Poverty

October 2024

Laboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi Province, 030801, People's Republic of China.

Background: Toxocara canis, the most prevalent helminth in dogs and other canines, is one of the socioeconomically important zoonotic parasites, particularly affecting pediatric and adolescent populations in impoverished communities. However, limited information is available regarding the proteomes of female and male adult T. canis.

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Clinical and laboratory characteristics of Toxocara canis infection among children in Ho Chi Minh City, Vietnam.

Trans R Soc Trop Med Hyg

September 2024

Department of Family Medicine, Faculty of Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, 2 Duong Quang Trung Str., Dist 10, 72500, Vietnam.

Article Synopsis
  • * Out of the participants, 14.2% tested positive for T. canis antibodies, with common symptoms being itching (10.1%) and abdominal pain (8.2%); high eosinophil counts were also observed.
  • * The research established that elevated IgE levels and eosinophil counts can help predict T. canis infection, suggesting that blood tests should be done when kids show related symptoms.
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Toxocara canis larvae are one of the most overlooked agents of nervous system infection in paratenic hosts. Previous studies in mouse models have shown that infection with various (mainly high) numbers of larvae leads to neurobehavioral disturbances and pathological changes. Our study investigated whether the infection with low and moderate numbers of larvae could affect the physical condition, motor skills, and pathogenesis in the brains of experimentally infected mice.

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Article Synopsis
  • - The study aimed to evaluate the prevalence of Toxoplasma gondii and Toxocara spp. infections among police dogs and their trainers in Tehran, Iran, since no prior studies had been conducted in this area.
  • - Researchers collected 150 samples consisting of blood and fecal samples from police dogs and blood samples from their trainers, using various tests such as the Modified Agglutination Test (MAT) and molecular techniques to detect specific parasites.
  • - The findings indicated a prevalence of T. gondii at 4% in dogs and 10% in trainers, and Toxocara spp. was found in 6% of trainer samples; there were no significant associations between infections and the examined variables. *
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Toxoplasma gondii and Toxocara spp. zoonotic infections may cause severe systemic and ocular illness in infected individuals. Cats play a significant role in environmental contamination and the transmission of parasites.

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The Red Reflex Test and Leukocoria in Childhood.

Acta Med Port

September 2024

Department of Ophthalmology. Unidade Local de Saúde de São João. Porto.; Department of Surgery and Physiology. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.

The red reflex test, performed using a direct ophthalmoscope, serves as a critical diagnostic tool in identifying various ocular conditions. These conditions encompass retinal anomalies (such as retinoblastoma, Coats disease, retinopathy of prematurity, familial exudative vitreoretinopathy, myelinated nerve fibers, ocular toxocariasis, ocular toxoplasmosis, retinochoroidal coloboma, astrocytic, and combined hamartoma), vitreous abnormalities (including persistent fetal vasculature), lens issues (like cataract), anterior chamber and corneal conditions (comprising dysgenesis of the anterior segment, congenital glaucoma, birth trauma), and tear film disturbances. During this examination, the presence of leukocoria, characterized by a white pupillary reflex, can suggest the presence of underlying conditions.

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Toxocariasis and Strongyloidiasis as Triggering Factors for Wells' Syndrome.

Clin Cosmet Investig Dermatol

July 2024

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia.

Article Synopsis
  • Wells' syndrome is a rare skin condition marked by itchy, red lesions and swelling, often linked to high eosinophil levels and sometimes triggered by parasitic infections.
  • A case study in Indonesia reports a 27-year-old male who experienced recurrent painful rashes, fever, and diarrhea, ultimately diagnosed with Wells' syndrome after identifying eosinophilia and conducting histopathological tests.
  • The patient was treated for strongyloidiasis with albendazole, leading to improvement within two weeks, highlighting the importance of accurate diagnosis through clinical and pathological evaluations.
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This study aimed to evaluate the efficacy and safety of intravitreal dexamethasone implants in the treatment of ocular toxocariasis (OT). A retrospective analysis was performed on 6 cases in which laboratory tests diagnosed OT. All patients were administered with intravitreal dexamethasone implants with or without vitrectomy.

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Background: Toxocariasis is a zoonotic disease caused by the larvae of or . Patients with schizophrenia may be at higher risk of infection, possibly due to their cognitive and personal self-care impairments. We aimed to assess the association between spp.

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Article Synopsis
  • An indirect enzyme-linked immunosorbent assay (ELISA) was developed to detect specific IgG antibodies against Toxocara canis and Toxocara cati in patients with toxocariasis, analyzing serum samples.
  • The study calculated sensitivity, specificity, and predictive values for both T. canis and T. cati, showing excellent sensitivity (100% for T. canis and 97% for T. cati) and decent specificity (82% for both).
  • Five common immunoreactive bands were identified, with T. canis showing approximately twice the immune response compared to T. cati, indicating different immunological profiles in their somatic antigens.
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Toxocariasis is a zoonotic parasitic infection with worldwide distribution and high impact on human health. It has a limited clinical resolution with the available drugs, making it challenging to treat. Quercetin, which possesses biological and pharmacological qualities including antiparasitic, antioxidant, and anticancer activities, is a possible substitute for the current medications.

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Fatal Hymenolepis nana-associated visceral larva migrans in captive juvenile white-tailed antsangies (Brachytarsomysalbicauda).

J Comp Pathol

July 2024

International Zoo Veterinary Group, Station House, Parkwood Street, Keighley BD21 4NQ, UK. Electronic address:

Article Synopsis
  • White-tailed antsangies, a type of Madagascan rodent, were found to have an outbreak of H. nana, a type of tapeworm, marking the first recorded case in this species.
  • The examination of the affected rodents revealed cysticerci (larval form of the tapeworm) in multiple organs, including the intestines and liver, and identified gross lesions through histopathological methods.
  • DNA testing confirmed the presence of H. nana in all cases, suggesting that these infections may lead to unique pathological features like visceral larva migrans in white-tailed antsangies, different from typical rodent hosts.
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Background: Human toxocariasis (HT) is a zoonotic disease with a global expansion. Contaminated soil with spp. eggs is the main source of human infection, which may lead to severe complications depending on the organs invaded by migrating larvae.

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Article Synopsis
  • Toxocariasis is a zoonotic infection from dog and cat larvae that can pose serious health risks to humans, with a case described involving a 21-year-old male who had close contact with a pet dog.
  • The patient's symptoms initially resembled a common liver abscess, with lab results showing elevated white blood cells and IgE levels, but persistent fever led to more testing revealing a Toxocara-induced liver abscess.
  • Successful treatment with albendazole demonstrated significant improvement, highlighting the importance of considering toxocariasis in liver abscess cases, especially in regions with high rates of infection, and the need for thorough diagnostic methods beyond serological tests.
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Association between Alzheimer's disease and Toxocara infection/exposure: a case-control study.

Trans R Soc Trop Med Hyg

November 2024

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Infections may contribute to Alzheimer's disease (AD) risk. Limited evidence suggests Toxocara spp. infection/exposure could influence AD development.

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Human toxocariasis is a neglected anthropozoonosis with global distribution. Treatment is based on the administration of anthelmintics; however, their effectiveness at the tissue level is low to moderate, necessitating the discovery of new drug candidates. Several groups of synthetic compounds, including coumarin derivatives, have demonstrated bioactivity against fungi, bacteria, and even parasites, such as Dactylogyrus intermedius, Leishmania major, and Plasmodium falciparum.

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Article Synopsis
  • Toxocariasis is a zoonotic infection caused by parasitic roundworms from dogs and cats that can lead to various health issues in humans, primarily mild febrile illness, but also severe cases affecting eyes and internal organs.
  • Research shows that the disease results in an estimated loss of 91,714 Disability-Adjusted Life Years (DALYs) annually worldwide, with a significant portion associated with cognitive impairment in children.
  • The study highlights a link between pet prevalence and human infection rates, indicates a substantial economic impact of around $2.5 billion annually, and calls for more research and targeted interventions to address this health concern.
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