Facial Contouring Through Jaw Exercises: A Report of Two Cases Examining Efficacy and Consumer Expectations.

This study examines the efficacy of jaw exercising products for facial contouring. The two individuals used a commercially available jaw exerciser for approximately three months, following the provided instructions. Neither case reported noticeable changes in jaw appearance based on subjective measurements.

Adolescent vs. Young Adult Idiopathic Scoliosis patients: how different are their two year postoperative radiographic and clinical outcomes?

Purpose: To compare the long-term outcomes among AIS (10-18 years) and young AdIS (YAdIS) (19-40 years) patients with minimum 2 year follow up.

Methods: A retrospective review of AIS and YAdIS patients who underwent primary corrective surgery at a single center was conducted. Demographic, radiographic, operative data, patient reported outcome measures (PROMs), including the ODI and SRS-22r, and long-term complications were collected.

Forensic Dermatology Expert Analytical Report: A New Frontier of Forensic Medicine.

Specialists in forensic medicine assist in crime scene investigations. The forensic medicine experts include anthropologists, ballistic analysts, entomologists, odontologists, and osteologists. The experts are usually not at the crime scene; they provide an evaluation of evidence that is sent to them.

Clinical and research applications of natural language processing for heart failure.

Natural language processing (NLP) is a burgeoning field of machine learning/artificial intelligence that focuses on the computational processing of human language. Researchers and clinicians are using NLP methods to advance the field of medicine in general and in heart failure (HF), in particular, by processing vast amounts of previously untapped semi-structured and unstructured textual data in electronic health records. NLP has several applications to clinical research, including dramatically improving processes for cohort assembly, disease phenotyping, and outcome ascertainment, among others.

Contact Lens Wear Alters Transcriptional Responses to in Both the Corneal Epithelium and the Bacteria.

Purpose: Healthy corneas resist colonization by virtually all microbes yet contact lens wear can predispose the cornea to sight-threatening infection with . Here, we explored how lens wear changes corneal epithelium transcriptional responses to and its impact on bacterial gene expression.

Methods: Male and female C57BL/6J mice were fitted with a contact lens on one eye for 24 h.

Development of a Real-Time Single-Leg Hop Movement Quality Assessment to Identify Lower-Extremity Biomechanical Risk Factors.

Context: The single-leg hop is based solely on performance with no measure of movement quality. The purpose of this study was to (1) develop a real-time screening tool to capture single-leg functional performance and movement quality and (2) to provide preliminary validation (criterion validity) of a trained clinician's real-time movement quality assessment with 3D kinematics.

Study Design: Cross-sectional.

Family planning behavior before and during the COVID-19 pandemic.

Objective: Contraception use and follow-up visit data from before and in two periods during the coronavirus disease-2019 (COVID-19) pandemic were compared to investigate change in behavior.

Material And Methods: A retrospective study of women aged 18-49 years from New York City during three one-year time periods: pre-COVID-19 pandemic [(COV-PRE); n=4,261], early COVID-19 pandemic when the COVID-19 vaccine was not available [(COV-VACNO); n=3,365], and later COVID-19 pandemic when the COVID-19 vaccine was available [(COV-VACAV); n=4,170].

Results: There were higher odds of implant use [odds ratio (OR): 1.

A scoping review and hypothetical framework about the interplay between oxytocin and eating disorders.

Introduction: Despite emerging evidence on oxytocin's role in eating disorders,there is a need for a comprehensive review to integrate findings across neurobiological, genetic, hormonal, and therapeutic dimensions. This scoping review synthesizes existing literature on OXT's role in EDs and proposes a new theoretical perspective based on diverse research findings.

Methods: In accordance with PRISMA guidelines, we systematically synthesized all peer-reviewed articles indexed on PubMed which focused on both OXT and EDs as of December 2023 (k = 32 studies, n = 1942 participants).

From I to We: The Evolution of Individual Students from Seven Health Professions Programs to a Functioning Interprofessional Team.

This study presents a qualitative thematic analysis of the conversations between students from clinical mental health counseling (CMHC), occupational therapy (OT), nursing, physician assistant (PA), physical therapy (PT), social work (SW), and speech-language pathology (SLP) programs at an interprofessional education (IPE) symposium. The analysis describes the evolution from individuals to a collaborative interprofessional team, capturing the evolution as it unfolded. During a 1-day IPE symposium, conversations from one table of 11 students and a faculty facilitator were recorded and analyzed.

Structural proteomics defines a sequential priming mechanism for the progesterone receptor.

The progesterone receptor (PR) is a steroid-responsive nuclear receptor with two isoforms: PR-A and PR-B. Disruption of PR-A:PR-B signaling is associated with breast cancer through interactions with oncogenic co-regulatory proteins (CoRs). However, molecular details of isoform-specific PR-CoR interactions remain poorly understood.

Association of Gene Variants with Adverse Perinatal Outcomes in COVID-19 Infected Pregnant Women in Kazakhstan.

SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptors located on membranes to enter host cells. Nevertheless, the gene primarily encodes for a zinc metalloproteinase, which is a part of the renin-angiotensin system (RAS). ACE2 downregulation results in the deregulation of RAS in favor of pro-fibrosis, pro-apoptosis, oxidative stress, pro-inflammation, aldosterone production and release, and blood vessel contraction axis.

Wait, Where's the Flynn Effect on the WAIS-5?

The recent release of the WAIS-5, a decade and a half after its predecessor, the WAIS-IV, raises immediate questions about the Flynn effect (FE). Does the traditional FE of points per decade in the U.S.

A mitochondrial redox switch licenses the onset of morphogenesis in animals.

Embryos undergo pre-gastrulation cleavage cycles to generate a critical cell mass before transitioning to morphogenesis. The molecular underpinnings of this transition have traditionally centered on zygotic chromatin remodeling and genome activation, as their repression can prevent downstream processes of differentiation and organogenesis. Despite precedents that oxygen depletion can similarly suspend development in early embryos, hinting at a pivotal role for oxygen metabolism in this transition, whether there is a chemical switch that licenses the onset of morphogenesis remains unknown.

A Review of Platelet-Rich Plasma Use in Patients Taking Non-steroidal Anti-inflammatory Drugs for Guideline Development.

Platelet-rich plasma (PRP) is an autologous blood product containing concentrated platelets, growth factors, and anti-inflammatory cytokines that promote healing and regeneration. Platelets release active components through a degranulation process, which is inhibited by certain nonsteroidal anti-inflammatory drugs (NSAIDs). Current deferral guidelines are not established, but NSAIDs are expected to have a time-dose relationship with platelet inhibition.

Determining Ideal Practices for Student Course Evaluations Using a Modified Delphi Approach.

Objective: While approaches for utilizing student course evaluations (SCEs) have been discussed in the literature, there remain opportunities to identify ideal practices for SCEs. Thus, the objective of this project was to generate consensus on best practices in creating, administering, and using SCEs.

Methods: A modified Delphi approach was utilized to generate a set of items based on the literature and prior work.

Plate-Based Measurement of Respiration by Isolated Mitochondria and by Intact Cells.

Measuring respiration rate can be a powerful way to assess energetic function in isolated mitochondria and intact cells. Current plate-based methods have several advantages over older suspension-based systems, including greater throughput and the requirement of only microgram quantities of material. In this chapter, we provide an update to our previously published methods for plate-based measurement of oxygen consumption in isolated adherent mitochondria in a 96-well format plate.