741 results match your criteria: "Topiwala National Medical College & BYL Nair Ch. Hospital[Affiliation]"
Indian J Psychiatry
November 2024
Department of Psychiatry, Murshidabad Medical College and Hospital, Murshidabad, West Bengal, India.
Background: There is lack of data on bipolar disorder (BD) type II from India.
Aim: To compare the demographic and clinical characteristics of patients with BD-I and BD-II using the data of the Bipolar Disorder Course and Outcome study from India (BiD-CoIN study).
Methodology: Using the data of the BiD-CoIN study, patients with BD-I and BD-II were compared for demographic and clinical variables.
World Neurosurg
December 2024
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA. Electronic address:
Background: The Spinal Instability Neoplastic Score (SINS) is used in determining instability in patients with spinal metastases. Intermediate scores of 7 to 12 suggest possible instability, but there are no clear guidelines to address patients with these scores.
Methods: We searched in PubMed, EMBASE, and Cochrane databases for studies that included patient demographics, tumor histology, surgical or radiotherapy management, and outcomes of patients with intermediate SINS.
Med J Armed Forces India
December 2024
Professor (Surgery), Topiwala National Medical College, Mumbai, Maharashtra, India.
Hydrocele of the Canal of Nuck is a rare inguinal-scrotal swelling that occurs primarily as a chronic painful lump in childhood or in young women. Here, we present a rare case of the same, presenting at an extreme of age and with a short history. An 85-year-old female patient presented with a progressive inguinal swelling for 2 months in a known case of decompensated cirrhosis of liver in form of ascites and portal cavernoma.
View Article and Find Full Text PDFIndian J Plast Surg
December 2024
Department of Plastic Surgery, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital, Mumbai, Maharashtra, India.
Convincing a patient who has undergone any aesthetic surgery to come for a long-term follow-up is extremely difficult. The result obtained after rhinoplasty usually stabilizes in the first year and it is unlikely to change after 2 years. The precision carving technique described in 2014 has been employed by us for the last several years.
View Article and Find Full Text PDFIndian J Plast Surg
December 2024
Aesthetique, Plastic and Cosmetic Surgery Centre, Gujarat, India.
The influence of Instagram, as a social media platform, in shaping perceptions of aesthetic surgery cannot be understated. The idea of a more "aesthetic" self cultivates a desire for cosmetic enhancements. This article underscores the profound impact of Instagram on aesthetic surgery, shedding light on both its fantasies and fallacies.
View Article and Find Full Text PDFIndian J Plast Surg
December 2024
Department of Plastic Surgery, Breach Candy Hospital, Mumbai, Maharashtra, India.
Augmentation rhinoplasty requires graft with substantial volume. In cases where patient is reluctant to use costal cartilage, this can be done using septum and conchal cartilage graft. Using the technique of "stacked cartilage graft" an assembly is made using septum and conchal cartilage for nasal augmentation and contour defects.
View Article and Find Full Text PDFJ Family Med Prim Care
November 2024
Department of Paediatrics, B.Y.L. Nair Hospital and Topiwala National Medical College, Mumbai, Maharashtra, India.
Background: Birth asphyxia is a major cause of neonatal mortality and neurological morbidity. This study was aimed to determine biochemical (sodium, potassium, and calcium) abnormalities and their correlation across different severities of perinatal asphyxia in term neonates.
Methods: This observational analytical study was conducted in term neonates with perinatal asphyxia admitted at the neonatal intensive care unit of a tertiary care centre for a period of 18 months.
Monaldi Arch Chest Dis
December 2024
Department of Clinical Pharmacology, Topiwala National Medical College And Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai.
The N-acetyltransferase 2 (NAT2) gene exhibits substantial genetic diversity, leading to distinct acetylator phenotypes among individuals. In this study, we determine NAT2 gene polymorphisms in tuberculosis (TB) patients and analyze serum isoniazid (INH) concentrations across the various genotypes. An observational prospective cohort study involving 217 patients with pulmonary or extrapulmonary TB was carried out.
View Article and Find Full Text PDFCureus
November 2024
Department of Gastroenterology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, IND.
A 12-year-old female, resident of western India, presented with a history of pruritus associated with jaundice for two months. On presentation, she had icterus with mild palpable hepatomegaly. Investigations revealed direct hyperbilirubinemia and elevated transaminases, while gamma-glutamyl transferase levels were normal.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Paediatrics, Topiwala National Medical College & B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra, India
Diagnosing hereditary spastic paraplegia (HSP) in paediatric patients can be challenging, especially when there is no positive family history. Children are often initially misdiagnosed with cerebral palsy due to the gradual progression of the disease and non-specific neuroimaging findings, despite the absence of perinatal insult. This misdiagnosis can prevent timely prenatal diagnosis, limiting the ability to make informed decisions about the pregnancy and to plan early interventions.
View Article and Find Full Text PDFCureus
November 2024
Medical Affairs, Sun Pharma Laboratories Limited, Mumbai, IND.
Introduction Fixed-dose combinations (FDCs) have the potential in glaucoma management to improve efficacy due to the complementary mechanism of action of the drugs as well as compliance while reducing adverse effects by minimizing exposure to preservatives and the financial burden on the patients. FDC of brinzolamide/timolol has demonstrated efficacy and safety in multinational phase 3 studies in primary open-angle glaucoma (POAG) and ocular hypertension. However, efficacy and safety in the Indian population are not known.
View Article and Find Full Text PDFJ Assoc Physicians India
December 2024
Professor of Medicine (Retd), Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital; Hon. Physician, Bhatia Hospital, Mumbai, Maharashtra, India.
Frank Macfarlane Burnet (1899-1985) was born in Victoria, Australia, and obtained his MD in 1924 from the University of Melbourne. Burnet spent 2 years in England at the Lister Institute, where he studied bacteriophages and earned a PhD in 1928. Returning to Australia, he worked at the Walter and Eliza Hall Institute; as a bacteriologist, he continued his research on phages.
View Article and Find Full Text PDFJ ASEAN Fed Endocr Soc
December 2024
Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, India.
Typically, primary hyperparathyroidism (PHPT) develops as a result of multiglandular hyperplasia, parathyroid cancer, or parathyroid adenoma. Patients usually present with skeletal manifestations such as low-trauma fractures. Osteitis fibrosa cystica (OFC) is a classic yet rare skeletal manifestation of advanced PHPT currently reported in less than 2% of patients.
View Article and Find Full Text PDFJ Indian Fed Neurorehabilit
August 2024
Bombay Hospital and Medical Research Center, Mumbai, India.
The organized provision of health services in India has been envisioned since 1946 by the recommendations from the Bhore committee. However, the policy and program strategies for the provision of good quality health care still lack effectiveness. Access to rehabilitation services for persons with disabilities continues to be a significant public health problem in India.
View Article and Find Full Text PDFJ Assoc Physicians India
November 2024
Professor (Retired), Department of Medicine, Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital; Honorable Physician, Bhatia Hospital, Mumbai, Maharashtra, India.
Corneille Heymans (1892-1968) was born in 1892 in Ghent, Belgium. Heymans received his doctor's degree in 1920 from the University of Ghent. He studied physiology in Paris, Lausanne, Vienna, and London under EH Starling and in the United States after graduation.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2024
Neurosurgeon, MGIMS, Wardha, India.
We describe a case of a 24 year old female who came with complaint of bilateral tinnitus, profound hearing loss, and weakness in both lower limbs which on imaging work up showed unilateral acoustic schwannoma, and spinal extramedullary intradural lesions at D8-D9 level giving the classical features of neurofibromatosis II along with cafe au lait spots, axillary freckling, cutaneous neurofibromas, which are unique to NF1. The purpose of this report is to discuss the study of a patient with classical features of both NF-I and NF-II, emphasizing the need for surveillance regarding sporadic mutations seen in NF I AND NF II genes, as well as genetic mosaicism to be kept in mind when diagnosing such patients.
View Article and Find Full Text PDFFetus in fetu (FIF) is a rare anomaly characterized by the presence of a monozygotic twin that becomes incorporated into the abdomen of its sibling during fetal development. FIF is a rare congenital condition typically identified in infancy. We present a case of FIF in a 16-year-old male, which is an extremely rare presentation during adolescence.
View Article and Find Full Text PDFBackground: Meningococcal disease remains an important public health problem globally. We assessed the non-inferiority and the lot-to-lot consistency of a pentavalent meningococcal ACYWX conjugate vaccine (NmCV-5; Serum Institute of India, Pune, India) versus a quadrivalent meningococcal ACWY conjugate vaccine (MenACWY-D) in healthy adults.
Methods: In this observer-blind, randomised, active-controlled, phase 2/3 study, healthy adults aged 18-85 years were recruited from nine hospitals across seven cities in India.
Cureus
October 2024
General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND.
Malignant gastrointestinal neuroectodermal tumor (GNET) are rare malignant mesenchymal tumors. The tumor can present with various symptoms like abdominal pain, anorexia, or small bowel obstruction. Here, we present a case of small intestinal GNET who presented with gastrointestinal bleed and hemoperitoneum, a rare presentation of this disease.
View Article and Find Full Text PDFMol Cell Endocrinol
January 2025
Department of Neuroendocrinology, ICMR-National Institute for Research in Reproductive and Child Health, Parel, Mumbai, 400012, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address:
Varicocele has been associated with reduced male fertility potential. Treatment modalities for varicocele improve semen parameters, yet more than 50% of cases remain infertile. Varicocele-induced heat and hypoxia stress may affect sperm mitochondrial functions, possibly leading to aberrant epigenetic modifications.
View Article and Find Full Text PDFPsychiatry Res
December 2024
Murshidabad Medical College and Hospital, Murshidabad, India.
Background: There is a lack of information on the long-term course and outcomes of bipolar disorder (BD) patients with seasonal affective disorder (SAD).
Aim: To compare the demographic and clinical profile of BD patients with and without SAD.
Methodology: Data from 773 BD patients with an illness duration of at least 10 years were collected from 14 tertiary care centers.
Cureus
September 2024
General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND.
Paraduodenal hernias, especially right sided, are extremely rare entities that are difficult to diagnose due to their uncommon presentation. Some may experience small bowel obstruction. Such patients will have a guarded prognosis if complicated by sepsis due to strangulation or perforation.
View Article and Find Full Text PDFTurk J Haematol
December 2024
YB Chavan College of Pharmacy, Department of Pharmaceutics, Aurangabad, India
J Assoc Physicians India
October 2024
Family Physician, Bengaluru, Karnataka, India.
Indian J Med Res
June 2024
Department of Clinical Pharmacology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai 400 008, Maharashtra, India.