Electrochemical Behavior of Glassy Carbon Electrodes Modified with Electropolymerized Film of N,N'-bis (2-thienylmethylene)-1,X-diaminobenzene toward Homovanillic Acid and 4-Hydroxyphenylacetic Acid.

This study evaluates different electrochemical behaviors of modified glassy carbon electrodes (GCEs) for detecting urinary biomarkers related to breast cancer, namely homovanillic acid (HVA) and 4-hydroxyphenylacetic acid (4HPA). The analysis was performed in the presence of common urinary interferents, creatinine and urea. Modification of bare GCEs was done through the electropolymerization of N,N'-bis (2-thienylmethylene)-1,X-diaminobenzene (X = 2, 3, 4) isomers, so-called BTMD.

An exuberant case of uremic stomatitis in an older adult.

Objective: To report the case of an older adult with uremic stomatitis.

Background: Uremic stomatitis is a rare condition, with only 57 cases documented in the literature. Gerodontologists may be unfamiliar with this condition.

Cerebellar control of targeted tongue movements.

The cerebellum is critical for coordinating movements related to eating, drinking and swallowing, all of which require proper control of the tongue. Cerebellar Purkinje cells can encode tongue movements, but it is unclear how their simple spikes and complex spikes induce changes in the shape of the tongue that contribute to goal-directed movements. To study these relations, we recorded and stimulated Purkinje cells in the vermis and hemispheres of mice during spontaneous licking from a stationary or moving water spout.

Quadroiliac Plane Block for Postoperative Pain Management in a Patient Undergoing Retrograde Intrarenal Surgery: A Case Report.

Opioid-free analgesia is crucial for high-risk patients, such as those with upper airway malignancies, to prevent respiratory complications. The Quadroiliac Plane Block (QIPB) offers an effective alternative. A 43-year-old female with base of tongue cancer underwent retrograde intrarenal surgery (RIRS) under spinal anesthesia.

Oral health-related knowledge, attitude and practices among nurses: a hospital-based questionnaire survey from a tertiary healthcare setting in Faridabad, India.

Background: Nurses play an integral part in the comprehensive delivery of healthcare services and contribute significantly to the success of public health initiatives. The knowledge, attitude and practices of nurses in the domain of oral health influence their own oral hygiene as well as that of the community. Their impact on overall oral health of the community is due to the fact that they provide health education as the primary contact of patients and their family members.

Aphthous-Like Stomatitis in a Patient Receiving Panitumumab.

Background: Panitumumab is an anti-epithelial growth factor receptor monoclonal antibody, approved for the treatment of metastatic colorectal cancer. Panitumumab has been more commonly associated with skin toxicity; oral adverse events have been scarcely reported in the literature. Herein, we present a case report of panitumumab-associated aphthous-like stomatitis.

Association between olfactory dysfunction and gustatory dysfunction: evidence from the National Health and Nutrition Examination Survey.

Background: Olfactory dysfunction (OD) and gustatory dysfunction (GD) are common among adults, with prevalence increasing significantly in older age groups. Both dysfunctions have negative effects on appetite, nutrition, social functioning and even environmental safety. OD and GD frequently coexist, indicating a possible close association between these conditions.

Association of Number of Oral bacteria with Ventilator-Associated Pneumonia and Delirium in Patients in the Intensive Care Unit.

Objectives: Ventilator-associated pneumonia (VAP) and delirium are major complications among patients in the intensive care unit (ICU). The impact of oral bacterial count on these conditions is not well understood. This study aimed to explore the association between oral bacterial load and the incidence of VAP and delirium in ICU patients.

Integrated Study of Fluorescence Enhancement in the Y176H Variant of Cyanobacterial Phytochrome Cph1.

Phytochromes are red-light-sensitive biliprotein photoreceptors that control a variety of physiological processes in plants, fungi, and bacteria. Lately, greater attention has been paid to these photoreceptors due to their potential as fluorescent probes for deep-tissue microscopy. Such fluorescing phytochromes have been generated by multiple amino acid substitutions in weakly fluorescent wild-type (WT) proteins.

[Study on the invasion of in tissues during carcinogenesis of oral mucosa].

To explore the differences in bacterial communities within tissues during the process of oral mucosal carcinogenesis, and analyze the relationship between the high-abundance species (Pi) and the occurrence and development of oral mucosal carcinogenesis. Fresh tissue samples were collected from patients diagnosed with oral leukoplakia (OLK), oral squamous cell carcinoma (OSCC), and healthy controls (HC) at Nanjing Stomatological Hospital from January 2022 to November 2024, following strict inclusion criteria. Bacterial DNA was extracted from these specimens, and the 2bRAD sequencing for microbiome (2bRAD-M) was employed to analyze and compare the α and β diversity, as well as the community composition of bacteria within tissues, aiming to identify specifically expressed bacteria.

The fourth family in the world with a novel variant in the ATP5MK gene: four siblings with complex V (ATP synthase) deficiency.

Mitochondrial Complex V (ATP synthase) deficiency nuclear type 6 (MC5DN6) is a progressive neurodegenerative disorder characterized by autosomal recessive inheritance and developmental regression, particularly in gross motor skills, which manifests in early childhood. This study aims to present the discovery of a novel variant in four male siblings aged 13 years 9 months to 25 years, making this the fourth family reported globally, while also raising awareness of rare mitochondrial diseases. Four individuals from the same family were retrospectively evaluated based on their demographic, clinical, laboratory, and molecular genetic data.

Advancing early detection of organ damage and cardiovascular risk prevention: the Suzhou cardiometabolic health study protocol - exploring the role of oral microbiome and metabolic profiling in risk stratification.

Background: Cardiovascular Disease (CVD) is the leading cause of global mortality, with its incidence rate rising year by year due to the prevalence of metabolic diseases. Existing primary and secondary prevention strategies for cardiovascular disease have limitations in identifying some high-risk groups, and 1.5-level prevention aims to achieve more precise intervention by early identification of subclinical target organ damage.

Cross-population tongue image features and tongue coating microbiome changes in the evolution of colorectal cancer.

Introduction: Tongue diagnosis, a cornerstone of Traditional Chinese Medicine (TCM), relies significantly on the assessment of tongue coating, which is used to evaluate Zang-fu organ functions, qi and blood dynamics, and the influence of pathogenic factors. This diagnostic method is integral to disease diagnosis and treatment in TCM. Recent research suggests a strong correlation between the characteristics of tongue coating and its microbial composition.

Outcomes of stretching exercises after lingual frenotomy in infants: A prospective, interventional study.

Objective: To evaluate the safety and efficacy of stretching exercises after frenotomy for ankyloglossia.

Study Design: Prospective cohort study.

Setting: Single academic tertiary care hospital.

Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia.

Oral squamous cell carcinoma (OSCC) is characterized by aggressiveness and a poor prognosis, in part because most patients are diagnosed during the later stages of the disease. B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), part of polycomb repressive complex 1 (PRC1), is a key transcription factor overexpressed in OSCC. Although increased BMI1 has been linked to tumor formation in mouse models of the disease, the molecular mechanisms have not been elucidated.

Early-stage immunoexpression of inflammatory, angiogenic, and survival markers in tongue epithelium of mice exposed to hookah smoke.

Objective: The objective was to evaluate the early-stage immunoexpression of markers (COX-2, NF-kB, VEGFR-1 and apoptotic index) related to inflammation, angiogenesis, and cell survival in the tongue dorsum epithelium of mice exposed to hookah smoke.

Materials And Methods: The sample consisted of Swiss mice (N = 20), female gender, aged 2 months, and approximately 25g each, four groups (n = 5) mice: group exposed to fresh air and groups exposed to hookah smoke for 7, 15, and 30 days. Tongues were embedded in paraffin.

Tongue Base Schwannoma Presenting With Dyspnea.

Schwannoma is a benign nerve sheath tumor arising from Schwann cells. Its exact etiology remains known. Tongue base schwannoma is a remarkably rare form of schwannoma.

Motor Imagery Practice to Improve Respiratory and Cough Function.

Motor imagery practice (MP), or visualizing performing a task without executing it, is an effective intervention for the limbs and tongue. However, MP of expiratory muscle strength training (EMST) and voluntary cough (VC) has not been explored. We examined the feasibility and impact of MP of VC and EMST on pulmonary and cough function in twenty community-dwelling adults.

Immediate effects of photobiomodulation on maximum tongue pressure: a randomized clinical study.

Purpose: To verify the immediate effects of infrared laser photobiomodulation on maximum tongue pressure.

Methods: This is a randomized clinical study with 72 healthy adults of both sexes, with a mean age of 24.6 years, standard deviation of 4.

Phenotypic variations of the human ear in the Basrah population.

<b>Introduction:</b> External ears are distinct and do not alter with age. Ear traits may be as reliable as fingerprints in identifying people. An external ear morphological analysis and observation of Basrah population ear features were undertaken to assess how beneficial the ear is for identification.

Novel insights into palatal shelf elevation dynamics in normal mouse embryos.

Development of the embryonic palate requires that the palatal shelves (PS), which extend from maxillary processes, to grow bilaterally and vertically alongside the tongue. This growth continues until embryonic day (E) 13.5, after which the PS elevate above the tongue and adhere, completing the process by E14.

Chronic Kidney Disease With Related Oral Health Problems and Alterations in the Tongue Microbiome Illustrated by a 15-Year-Old Girl: A Case Report.

Chronic kidney disease (CKD) is characterised by a gradual loss of kidney function over time and is often linked to oral health issues. This case illustrates typical conditions in young CKD patients based on a 15-year-old girl with CKD stage 4 and methylmalonic aciduria, severe gingivitis and hyperplasia of the gingiva, and a need for orthodontic treatment. Oral hygiene interventions, homecare instructions and deep cleaning under antibiotic shielding were necessary to improve the patient's oral health.

[Clinical research of mandibular embedded third molars extraction by root dislocation first method resulting in external root absorption of adjacent teeth].

Purpose: To evaluate the impact of impacted lower third molar(ILTM) extraction by root dislocation first method on bone formation in the distal middle of the second molar(M2M), pulp status and external root resorption (ERR).

Methods: A total of 64 patients who underwent ILTM extraction in the First Affiliated Hospital of Xinjiang Medical University from January 2023 to October 2023 were selected. Among them, 32 patients underwent root first removal of ILTM (experimental group), and 32 patients underwent crown first removal of ILTM (control group).

[Clinical study of cervical lymph node metastasis in oral tongue squamous carcinoma by a machine learning model based on contrast-enhanced CT radiomics].

Purpose: To investigate the value of machine learning model based on enhanced CT imaging features and clinical parameters in predicting cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC).

Methods: A total of 75 patients with TSCC who were treated in the Affiliated Stomatology Hospital of Nanjing Medical University from January 2015 to July 2022 were collected. All patients had complete clinical data, enhanced CT image data and postoperative cervical lymph node pathological examination results.