Community assembly and succession of the functional membrane biofilm in the anammox dynamic membrane bioreactor: Deterministic assembly of anammox bacteria.

The anammox dynamic membrane bioreactor (DMBR) exhibits potential for efficient nitrogen removal via anammox processes. The functional membrane biofilm in the anammox DMBR significantly enhances nitrogen removal, ensuring robust operation. Nevertheless, ecological mechanisms underpinning the nitrogen removal function of the membrane biofilm remain unclear.

How Do Nurses Decide on Missed Nursing Care? A Grounded Theory Study of Grassroots Arrangement of Nursing Care.

Aims: To explore the complete decision-making process and action logic of nurses making autonomous decisions that result in missed nursing care.

Background: The complex characteristics of patients in Intensive Care Units place higher demands on the allocation of nursing resources, as well as on the professional skills, resilience and ethics of nursing staff. Preventing missed nursing care is particularly crucial in Intensive Care Units.

Combined effect of the smartphone addiction and physical activity on the depressive symptoms in secondary school students: a cross sectional study in Shanghai, China.

Objective: This study aims to investigate the prevalence of smartphone addiction, physical activity levels, and depressive symptoms among secondary school students, and to analyze the combined impact of smartphone addiction and physical activity on depressive symptoms.

Methods: A cluster sampling method was employed in two secondary schools in the Jing'an District of Shanghai, China. Univariate analysis was used to compare the prevalence of depressive symptoms across different demographic characteristics.

Effectiveness of a theory-based tailored mHealth physical activity intervention for women undergoing chemotherapy for breast cancer: A quasi-experimental study.

Objectives: This study aimed to explore the effectiveness of the theory-based tailored mHealth physical activity (PA) intervention among patients with breast cancer undergoing chemotherapy.

Methods: A quasi-experimental study design was adopted. A total of 60 breast cancer patients were selected from two tertiary hospitals in Shanghai and Hangzhou City from September 2019 to August 2021.

Quantitative evaluation of accumulated and planned dose deviations in patients undergoing gated and non-gated lung stereotactic body radiation therapy patients: a retrospective analysis.

Background: Stereotactic body radiation therapy (SBRT) is crucial for treating early-stage inoperable non-small cell lung cancer (NSCLC) due to its precision and high-dose delivery. This study aimed to investigate the dosimetric deviations in gated (GR) versus non-gated radiotherapy (NGR), analyzing the impact of tumor location, target volume, and tumor motion range on dose distribution accuracy.

Methods: Sixty patients treated with either gated (n=30) or non-gated (n=30) SBRT for early-stage NSCLC were retrospectively analyzed.

EGFR inhibitors plus dabrafenib and trametinib in patients with EGFR-mutant lung cancer and resistance mediated by BRAF mutation: a multi-center real-world experience in China.

Background: The combination therapy of the B-Raf proto-oncogene (BRAF) inhibitor dabrafenib and the mitogen-activated protein kinase kinase (MEK) inhibitor Trametinib has shown favorable outcomes in patients initially identified with BRAF mutations. However, there are currently no large-scale study data focusing on the use of a triple therapy regimen of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) plus dabrafenib and trametinib in patients with newly concomitant BRAF mutations after acquiring resistance to EGFR-TKIs. Our study aimed to explore the efficacy and safety of the triple therapy regimen through a multi-center real-world experience.

Design and fabrication of 1D nanomaterials for electromagnetic wave absorption.

The design and fabrication of high-performance electromagnetic wave (EMW) absorbing materials are essential in developing electronic communication technology for defense and civilian applications. These materials function by interacting with EMWs, creating various effects such as polarization relaxation, magnetic resonance, and magnetic hysteresis in order to absorb EMWs. Significant progress has been made to improve the dimensional performance of such materials, emphasizing the 'thin, light, broad, and strong' functional specifications.

Metabolic response to burn injury: a comprehensive bibliometric study.

Objective: Burns lead to systemic changes manifested by systemic disturbances in water-electrolyte balance and systemic metabolic and inflammatory responses. The hypermetabolic response after a burn injury relies on metabolic, hormonal, and inflammatory dysregulation mechanisms. This study aimed to provide a comprehensive bibliometric analysis of the burn metabolism research field, identifying key trends, influential contributors, and emerging research hotspots to inform future investigative efforts.

Silica Nanoparticles Modified by Biphenyl Groups for Crack-Free Coating on Synthetic Paper.

Water-based acrylic emulsions are a crucial component of water-based ink. Preventing visible cracks in emulsion coating during drying is a great challenge due to the high polarity and high surface tension of water. Herein, we propose that the cracking resistance of the coating can be enhanced through the incorporation of hydrophobic silica nanoparticles.

Rapid Determination of Water-Soluble Vitamins in Human Serum by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry.

Water-soluble vitamins play essential roles in normal body functions and metabolic activities. However, few methods have simultaneously measured all nine water-soluble vitamins in biological matrices. In this study, we developed a sensitive and accurate method for the simultaneous measurement of thiamine (B1), riboflavin (B2), nicotinamide (B3), pantothenic acid (B5), 4-pyridoxic acid (B6), biotin (B7), 5-methyltetrahydrofolic acid (B9), ascorbic acid (VC), and methylmalonic acid (MMA) in human serum.

B4GALNT1 Regulates Hepatocellular Carcinoma Cell Proliferation and Apoptosis via the PI3K-AKT-mTOR Pathway.

Background: Hepatocellular carcinoma (HCC) is a ubiquitous malignancy linked to significant mortality. The abnormal expression of β-1,4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) seemed to be implicated in tumorigenesis. Nonetheless, this enzyme's roles in HCC are unclear.

Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis.

Background: Enolase 1 (ENO1) is a conserved glycolytic enzyme that regulates glycolysis metabolism. However, its role beyond glycolysis in the pathophysiology of multiple myeloma (MM) remains largely elusive. Herein, this study aimed to elucidate the function of ENO1 in MM, particularly its impact on mitophagy under bortezomib-induced apoptosis.

Synergistic Adhesion and Shape Deformation in Nanowire-Structured Liquid Crystal Elastomers.

Nature provides many examples of the benefits of nanoscopic surface structures in areas of adhesion and antifouling. Herein, the design, fabrication, and characterization of liquid crystal elastomer (LCE) films are presented with nanowire surface structures that exhibit tunable stimuli-responsive deformations and enhanced adhesion properties. The LCE films are shown to curl toward the side with the nanowires when stimulated by heat or organic solvent vapors.

Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3 tissue-resident CD4 T cells in acute liver injury.

Acetaminophen (APAP) stands as one of the most prevalent triggers of drug-induced acute liver injury (ALI). The intricate modulation of immune system activation and inflammatory cascades by hepatic immune cells is paramount in managing liver injury and subsequent restoration. In this study, we employed an integrative approach that fused our proprietary flow cytometry analyses across various time points post-APAP injury with publicly available single-cell RNA sequencing (scRNA-seq) datasets, encompassing time-series data from liver tissue of mice subjected to APAP intoxication.

Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch.

Chronic itch remains a clinically challenging condition with limited therapeutic efficacy, posing a significant burden on patients' quality of life. Despite its prevalence, the underlying neural mechanisms remain poorly understood. In this study, we explored the synaptic relationships between neuropeptide Y (NPY) neurons and gastrin-releasing peptide receptor (GRPR) neurons in the spinal cord.

Is simpler better? Semantic content modulates the emotional prosody perception in Mandarin-speaking children with autism spectrum disorder.

Introduction: It is still under debate whether and how semantic content will modulate the emotional prosody perception in children with autism spectrum disorder (ASD). The current study aimed to investigate the issue using two experiments by systematically manipulating semantic information in Chinese disyllabic words.

Method: The present study explored the potential modulation of semantic content complexity on emotional prosody perception in Mandarin-speaking children with ASD.

Motion analysis for the evaluation of dynamic spasticity during walking: A systematic scoping review.

Background: Three-dimensional (3D) gait analysis has the potential to assess dynamic spasticity (DS). However, little is known about which parameters can be utilized for assessment.

Objective: To evaluate the application of 3D gait analysis in assessing DS during walking and to identify the most relevant parameters for clinical practice.

TWEAK-Fn14 signaling protects mice from pulmonary fibrosis by inhibiting fibroblast activation and recruiting pro-regenerative macrophages.

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by excess accumulation of the extracellular matrix (ECM). The role of macrophage-fibroblast crosstalk in lung fibrogenesis is incompletely understood. Here we found that fibroblast growth factor-inducible molecule 14 (Fn14), the receptor for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is highly induced in myofibroblasts in the lungs of IPF patients and the bleomycin-induced lung fibrosis model.

Colorectal cancer in Lynch syndrome families: consequences of gene germline mutations and the gut microbiota.

Background: Lynch syndrome (LS)-associated colorectal cancer (CRC) always ascribes to pathogenic germline mutations in mismatch repair (MMR) genes. However, the penetrance of CRC varies among those with the same MMR gene mutation. Thus, we hypothesized that the gut microbiota is also involved in CRC development in LS families.

The clean analysis process of Mn for industries: a comparative study on direct determination of high-concentration Mn in solution using spectrophotometry.

Mn is an essential cation extensively utilized in various industrial processes, including electrolytic manganese production, manganese dioxide manufacturing, and zinc processing. It also poses significant environmental challenges as a primary pollutant in Mn-containing wastewater and hazardous materials. Effective monitoring and control of Mn in these processes are vital for improving resource conversion efficiency and minimizing pollutant production.

Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells.

As a novel form of nonapoptotic cell death, ferroptosis is developing into a promising therapeutic target of dedifferentiating and therapy-refractory cancers. However, its application in pancreatic cancer is still unknown. In the preliminary research, we found that F-box and WD repeat domain-containing 7 (FBW7) inhibited the migration and proliferation of pancreatic cancer cells through its substrate c-Myc.

Electrospun meshes for abdominal wall hernia repair: Potential and challenges.

Surgical meshes are widely used in abdominal wall hernia repairs. However, consensus on mesh treatment remains elusive due to varying repair outcomes, especially with the introduction of new meshes, posing a substantial challenge for surgeons. Addressing these issues requires communicating the features of emerging candidates with a focus on clinical considerations.

Polydopamine-coated montmorillonite micro/nanoparticles enhanced pectin-based sprayable multifunctional liquid mulching films: Wind erosion resistance, water retention, and temperature increase/heat preservation properties.

Natural biopolymer-based liquid mulching films (LMF) have received widespread attention, whereas the fragile structure and limited functionality have severely restricted their application. Herein, polydopamine-coated montmorillonite micro/nanoparticles enhanced pectin-based sprayable multifunctional liquid mulching films (P-MMT@PDA LMF) were prepared. Dopamine has abundant active sites, and its self-polymerization onto the surface of MMT improves the compatibility of MMT with pectin chains, facilitates the homogeneous dispersion of MMT@PDA in pectin polymers, and makes them more tightly entangled through hydrogen bonding.

Transcriptional regulation of Rankl by Txnip-Ecd in aging and diabetic related osteoporosis.

Introduction: Bone homeostasis between osteoclast bone resorption and osteoblastic bone formation is tightly regulated by a series of factors such as the receptor activator of nuclear factor-κB ligand (RANKL). Denosumab that neutralizes RANKL is effective and widely applied in the treatment of postmenopausal osteoporosis. However, factors that participated in the RANKL-related bone remodeling process in primary and secondary osteoporosis are less known.