Morusacerane: A new gammacerane triterpenoid from the trunk of linn. with -glucosidase inhibitory activity.

This phytochemistry investigation on the trunk of L. resulted in the isolation of three triterpenoids, including a new gammacerane triterpenoid - morusacerane (); along with two known compounds of betulinic acid () and ursolic acid (). The structure elucidation was thoroughly conducted based on 1D, 2D-NMR and HRESIMS spectra, followed by a comparison with existing literatures.

Testusterol, a new sterol of the sponge species from Phu Quoc island, Vietnam.

A new sterol, named testusterol (), and five known compounds () were isolated from the -hexane and dichloromethane extracts of the sponge species . Their chemical structures were elucidated based on extensive spectroscopic analyses (1D, 2D NMR, ESIMS and HRESIMS) and comparison with published data. The results of test (utilizing brine shrimp LEACH) showed that three extracts ethanol, dichloromethane, and ethanol/water, significantly inhibited with LC values ranging from 6.

Structural modification of tanshinone IIA and their α-glucosidase inhibitory activity.

α-Glucosidase is one of the therapeutic approaches for treating type 2 diabetes mellitus. Almost 95 % of diabetes patients worldwide have been diagnosed with type 2 diabetes, resulting in 1.5 million fatalities each year.

A novel and effective method for solving the router nodes placement in wireless mesh networks using reinforcement learning.

Router nodes placement (RNP) is an important issue in the design and implementation of wireless mesh networks (WMN). This is known as an P-hard problem, which cannot be solved using conventional algorithms. Consequently, approximate optimization strategies are commonly used to solve this problem.

Omics analysis unveils changes in the metabolome and lipidome of Caenorhabditis elegans upon polydopamine exposure.

Polydopamine (PDA) is an insoluble biopolymer with a dark brown-black color that forms through the autoxidation of dopamine. Because of its outstanding biocompatibility and durability, PDA holds enormous promise for various applications, both in the biomedical and non-medical domains. To ensure human safety, protect health, and minimize environmental impacts, the assessment of PDA toxicity is important.

Sesquiterpenoids and hexanorcucurbitacin from agarwood with anti-inflammatory effects by inhibiting the STAT1/AKT/MAPK/NLRP3 pathway.

Seven unknown compounds 1-7, including four sesquiterpenoids, one azulene-type, one indene-type, and one rare hexanorcucurbitacin, together with eleven knowns ones (8-16), were isolated from the agarwood chips of . The structures of the isolated compounds were elucidated by extensive spectroscopic methods such as mass spectrometry, UV, IR, NMR spectroscopy. The precise stereo-chemical configurations of new compounds were determined by calculated ECD spectra data, as well as a single-crystal X-ray diffraction analysis.

Adjustment of optical absorption in phosphorene through electron-phonon coupling and an electric field.

This study investigates the optical absorption of monolayer phosphorene, focusing on its response to the electron-phonon coupling (EPC) and an electric field. Using a tight-binding Hamiltonian model based on the Barišic-Labbe-Friedel-Su-Schrieffer-Heeger model and the Kubo formula, we calculate the electronic band structure and optical absorption characteristics. The anisotropic dispersion of carriers along armchair and zigzag directions leads to distinct optical responses.

Innovative numerical modeling for predicting soil relaxation in the design of twin circular culverts.

This study presents a finite difference model for analyzing ground stability and settlement of twin circular culverts in undrained clay. The model is verified through simulations of soil movement and relaxation around a tunnel-boring machine's shield. Stability numbers and ground settlement are evaluated across various culvert geometries and soil ratios and compared to rigorous solutions and previous models.

Cyclosporine A-induced systemic metabolic perturbations in rats: A comprehensive metabolome analysis.

A better understanding of cyclosporine A (CsA)-induced nephro- and hepatotoxicity at the molecular level is necessary for safe and effective use. Utilizing a sophisticated study design, this study explored metabolic alterations after long-term CsA treatment in vivo. Rats were exposed to CsA with 4, 10, and 25 mg/kg for 4 weeks and then sacrificed to obtain liver, kidney, urine, and serum for untargeted metabolomics analysis.

Triple-Hybrid BioScaffold Based on Silk Fibroin, Chitosan, and nano-Biphasic Calcium Phosphates: Preparation, Characterization of Physiochemical and Biopharmaceutical Properties.

Bioscaffolds, which promote cell regeneration and restore tissues' functions, have emerged as significant need in clinic. The hybrid of several biomaterials in a bioscaffold renders clinically advanced and relevant properties for applications yet add challenges in cost efficiency, production, and clinical investigation. This study proposes a facile and sustainable method to formulate a triple-hybrid bioscaffold based on Vietnamese cocoon origin Silk Fibroin, Chitosan, and nano-Biphasic Calcium Phosphates (nano-BCP) that can be easily molded, has high porosity (55-80%), and swelling capacity that facilitates cell proliferation and nutrient diffusion.

Assessing sigmoidal function on memristive maps.

Memristors offer a crucial element for constructing discrete maps that have garnered significant attention in complex dynamics and various potential applications. In this study, we have integrated memristive and sigmoidal function to propose innovative mapping techniques. Our research confirms that the amalgamation of memristor and sigmoidal functions represents a promising approach for creating both 2D and 3D maps.

A new 3,4-seco-isopimarane and three new isopimarane diterpenoids from Kaempferia champasakensis collected from Vietnam and their cytotoxic activities.

A phytochemical investigation of Kaempferia champasakensis rhizomes led to the isolation of a new 3,4-seco-isopimarane diterpene, kaempferiol A (1), and three new isopimarane diterpenes, kaempferiols B-D (2-4), together with six known isopimarane diterpenes (5-10). The structures of 1-4 were elucidated by extensive spectroscopic analyses, including HR-ESI-MS, UV, IR, and 1D and 2D NMR. The absolute configurations of 1, 3, and 4 were determined by ECD calculations, while that of 2 was established using the modified Mosher method.

Two New Benzoquinone Derivatives from Vietnamese Knema globularia Stems.

The chemical investigation of the stems of Knema globularia led to the isolation of two new benzoquinones derivatives, embenones A and B (1 and 2), along with three known compounds (3-5). The structures of the isolated compounds were determined using spectroscopic techniques, including HRESIMS, 1D and 2D NMR, in conjunction with comparison to existing literature data. Compounds 1 and 2 represent new carbon skeletons in nature.

Numerical entropy analysis of MHD electro-osmotic flow of peristaltic movement in a nanofluid.

The present study investigates the MHD electro-osmotic flow of entropy generation analysis for peristaltic movement in a nanofluid with temperature-dependent viscosity. Long wavelengths, i.e.

A bibliometric literature review of stock price forecasting: From statistical model to deep learning approach.

We introduce a comprehensive analysis of several approaches used in stock price forecasting, including statistical, machine learning, and deep learning models. The advantages and limitations of these models are discussed to provide an insight into stock price forecasting. Traditional statistical methods, such as the autoregressive integrated moving average and its variants, are recognized for their efficiency, but they also have some limitations in addressing non-linear problems and providing long-term forecasts.

Correction: Nguyen et al. Green Silver Nanoparticles Formed by , , and Leaf Extracts and the Antifungal Activity. 2020, , 542.

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Optimal placement and operation of soft open points, capacitors, and renewable distributed generators in distribution power networks to reduce total one-year energy loss.

The paper optimizes the placement of soft open points (SOPs) devices, shunt capacitor banks (SCBs), and distributed generators (DGs) in the IEEE 69-node distribution power grid for reducing the power loss of a single hour and total energy losses of one year. EO is proven to be more effective than previous methods and three other applied algorithms, including the Coot optimization algorithm (COOT), Modified weight inertia factor and modified acceleration coefficients-based particle swarm optimization (CFPSO), and Tunicate swarm algorithm (TSA). So, EO is applied for the last case considering one SOPs, one wind turbine (WT), two solar photovoltaic systems (PVs), and two SCBs over one year with twelve months and 24 h each month.

Precise cuts for tailoring chromene-phenyl COX inhibitors with Ligand Designer.

Cyclooxygenases 1 and 2 (COX-1/2) are enzymes renowned for inducing inflammatory responses through the production of prostaglandins. Thus, the development of COX inhibitors has been a promising approach for identifying compounds with anti-inflammatory potential. In this study, we designed 27 new compounds (1-27) based on the structure of a previously known COX inhibitor, using the Ligand Designer tool.

Thermal and hydraulic performance of ZnO/EG based nanofluids in mini tubes of different diameters: An experimental investigation.

The present experimental study investigates the thermal and hydraulic performance of Ethylene Glycol (EG)-based ZnO nanofluids (NFs) in circular minichannel test sections, each of 330 mm in length and 1.0-2.0 mm inner diameters.

Xanthine oxidase inhibition study of isolated secondary metabolites from (Bignoniaceae): and approach.

Xanthine oxidase (XO) has been widely recognized as a pivotal enzyme in developing hyperuricemia, primarily contributing to the excessive production of uric acid during purine metabolism in the liver. One of the standard treatment approaches involves reducing uric acid levels by inhibiting XO activity. In this study, the leaf extract of , traditionally used in folk medicine, was found to inhibit XO activity in the ethyl acetate and butanol fractions at a concentration of 100 µg/mL, their values were 78.

Adaptive neuro-fuzzy inference system for forecasting corrosion rates of automotive parts in biodiesel environment.

It is precarious to scrutinize the impacts of operational parameters on corrosion when choosing materials for the green diesel and automotive industries. This was the original study to showcase an optimization stratagem for abating corrosion rates (CRs) of automotive parts (APs) explicitly copper and brass in a biodiesel environment, adopting novel Response Surface Methodology (RSM) and Adaptive Neuro-Fuzzy Inference System (ANFIS).To model CRs, the RSM and ANFIS were utilized.

Identification and -glucosidase inhibitory activity evaluation of two new coumarins derived from J. R. Drumm.

Five coumarins were isolated from the heartwood of , which included two newly discovered compounds, namely 11-hydroxypopulene E () and mansorin D (), along with three previously identified compounds. The structures were determined through the utilisation of comprehensive spectroscopic data, ECD calculations, and a thorough comparison with existing literature data. The -glucosidase inhibitory activities of all isolated compounds were assessed in yeast.

The effects of free trade agreements on the stock market: Evidence from Vietnam.

This study examines the effects of news events related to the European Union-Vietnam Free Trade Agreement (EVFTA) on the Vietnam stock market from 2010 to 2020. We calculate sectoral abnormal returns prior to, during, and after announcements and find that the Vietnamese stock market is susceptible to these events. We discovered that the announcement had a negative impact on the market, which might diminish the effectiveness of the Agreement.