6 results match your criteria: "Tommy's Centre for Miscarriage Research[Affiliation]"

Article Synopsis
  • Pregnant women infected with SARS-CoV-2 face increased risks, including preterm birth and higher rates of stillbirth or neonatal admissions, highlighting ongoing concerns even after the WHO declared an end to the COVID-19 pandemic in May 2023.
  • A systematic review was performed to analyze the prevalence of early pregnancy loss in women with SARS-CoV-2 and compare these results to those of non-infected pregnant women.
  • The review included various studies that reported pregnancy losses before 20 weeks, as well as data on ectopic pregnancies and pregnancy terminations, ensuring a comprehensive examination of the impact of SARS-CoV-2 on early pregnancy outcomes.
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TPO antibody positivity and adverse pregnancy outcomes.

Best Pract Res Clin Endocrinol Metab

July 2020

Institute of Metabolism and Systems Research, College of Medical & Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK; Tommy's Centre for Miscarriage Research, College of Medical & Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK; Centre for Women's and Newborn Health, Birmingham Women's and Children's Foundation Trust, Edgbaston, Birmingham, B15 2TG, UK.

Thyroid autoimmunity (TAI) is prevalent amongst women of reproductive age. TAI describes the presence of circulating anti-thyroid autoantibodies that are targeted against the thyroid, with or without thyroid dysfunction. Thyroid peroxidase antibodies (TPOAb) are the most common anti-thyroid autoantibodies.

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The Prevalence of Thyroid Dysfunction and Autoimmunity in Women With History of Miscarriage or Subfertility.

J Clin Endocrinol Metab

August 2020

Institute of Metabolism and Systems Research, College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK.

Article Synopsis
  • - A study assessed thyroid dysfunction in asymptomatic women aged 16 to 41 who have experienced miscarriage or subfertility while trying to conceive, involving nearly 20,000 participants across UK hospitals from 2011 to 2016.
  • - The study found that 4.8% of women had abnormal thyroid function, with 0.2% having overt hypothyroidism and 0.3% overt hyperthyroidism; notable rates of subclinical hypothyroidism increased significantly when TSH levels were defined more strictly.
  • - Factors linked to higher rates of thyroid dysfunction included a BMI of 35.0 kg/m² or higher, Asian ethnicity, and a history of subfertility, while 9.5%
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Outcomes in prevention and management of miscarriage trials: a systematic review.

BJOG

January 2019

Institute of Metabolism and Systems Research, College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK.

Background: There is a substantial body of research evaluating ways to prevent and manage miscarriage, but all studies do not report on the same outcomes.

Objective: To review systematically, outcomes reported in existing miscarriage trials.

Search Strategy: MEDLINE, Embase, CINAHL, and Cochrane were searched from inception until January 2017.

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