615 results match your criteria: "Tolosa-Hunt Syndrome"
Ital J Pediatr
June 2022
Department of Clinical and Experimental Medicine, Unit of Rare Diseases of the Nervous System in Childhood, Section of Paediatrics and Child Neuropsychiatry, University of Catania, Catania, Italy.
Background: Ophthalmoplegic migraine, renamed "Recurrent Painful Ophthalmoplegic Neuropathy" (RPON) in 2013 by the International Headache Society is a rare neurologic disorder characterized by recurrent attacks of ophthalmoplegia associated to ipsilateral headache. The etiology is still unknown. Typical magnetic resonance imaging findings show a focal nerve thickening and contrast enhancement.
View Article and Find Full Text PDFOxf Med Case Reports
May 2022
Department of Ophthalmology, Aleppo University Hospital, Aleppo, Syria.
We are presenting a rare case of an acute complete external ophthalmoplegia with positive polymerase chain reaction (PCR) for SARS-CoV-2. Our case is the first case that depicts development of Tolosa-Hunt Syndrome (THS) following infection with COVID-19, with a challenging diagnosis and spontaneous improvement. A 65-year-old diabetic female presented with a complete external ophthalmopegia in the left eye and a severe left-sided headache.
View Article and Find Full Text PDFJ Neuroophthalmol
June 2022
Department of Neurology (IL, ML), Division of Neuroimmunology and Neuroinfectious Disease, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; and Treadwell Virtual Library for the Massachusetts General Hospital (ML), Boston, Massachusetts.
Background: A worldwide mass vaccination campaign against the coronavirus disease 2019 (COVID-19) pandemic is currently underway. Although the safety data of the clinical trials did not report specific concerns regarding neuro-ophthalmological adverse events, they involved a limited number of individuals and were conducted over a relatively short time. The aim of the current review is to summarize the available postmarketing data regarding the occurrence of neuro-ophthalmological and other ocular complications of the COVID-19 vaccines.
View Article and Find Full Text PDFRinsho Shinkeigaku
April 2022
Department of Neurology, Anti-aging and Vascular medicine, Division of Internal Medicine, National Defense Medical College.
The patient was a 14-year-old boy with two previous episodes of self-remitting right ophthalmoplegia with right temporal pain at ages 9 and 12. In 2019, he developed right eyelid ptosis and diplopia 2 days after a pulsating right-sided temporoparietal headache. Recurrent headaches with ophthalmoplegia responded to high-dose steroid therapy, and the clinical features resembled recurrent painful ophthalmoplegic neuropathy (RPON).
View Article and Find Full Text PDFBMC Endocr Disord
March 2022
The First Department of Medicine, Wakayama Medical University, Wakayama, Japan.
Background: Early diagnosis of lymphoma involving the central nervous system is sometimes difficult but emergent to avoid the delay of therapeutic initiation. Pituitary insufficiencies are usually associated with lymphoma in the pituitary gland. There have been no cases of lymphoma originating from extra pituitary gland with hypopituitarism that simultaneously presenting unilateral upper cranial nerve palsies and ophthalmalgia.
View Article and Find Full Text PDFJ Yeungnam Med Sci
April 2023
Department of Neurology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Invasive sphenoid sinus aspergillosis can mimic Tolosa-Hunt syndrome (THS), leading to frequent misdiagnoses and potentially fatal consequences. We report a case of invasive sphenoid sinus aspergillosis initially misdiagnosed as THS. A 79-year-old man presented with right periorbital pain, ophthalmoplegia, and loss of vision.
View Article and Find Full Text PDFEur Neurol
August 2022
Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Background: Several case series of patients with Tolosa-Hunt syndrome have been described in the literature; however, few studies have focused on the cerebrospinal fluid (CSF) characteristics. This study aimed to analyse the CSF characteristics of patients with Tolosa-Hunt syndrome.
Methods: Fifty-five patients who fulfilled the 3rd Edition of the International Classification of Headache Disorders diagnostic criteria for Tolosa-Hunt syndrome were included in this study.
BMJ Case Rep
March 2022
Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Tolosa-Hunt syndrome is understood as a steroid-responsive, relapsing-remitting, unilateral headache disorder associated with ipsilateral cranial neuropathies, of a probable granulomatous aetiology. The diagnosis is made clinically from the history and examination, supported by appropriate imaging. Here the authors report a case of Tolosa-Hunt syndrome with a headache phenotype mimicking a trigeminal autonomic cephalalgias (hemicrania continua), and serial MRI studies showing a stable enlarged pituitary.
View Article and Find Full Text PDFSurg Neurol Int
January 2022
Department of Neurosurgery, Tokai University Hachioji Hospital, Ishikawamachi, Hachioji, Tokyo, Japan.
Background: The diagnostic criteria for Tolosa-Hunt syndrome (THS) were updated in 2013 in the 3 Edition of the International Classification of Headache Disorders. It is now possible to diagnose THS based on the presence of granulomatous inflammation demonstrated on magnetic resonance imaging (MRI) without confirmation by biopsy. No previous study has reported the use of arterial spin labeling (ASL) perfusion MRI for diagnosing THS.
View Article and Find Full Text PDFCureus
December 2021
Department of Rheumatology, Brown University, Warren Alpert Medical School, Providence, USA.
Tolosa-Hunt syndrome (THS) is a rare neuro-immunological disorder characterized by severe periorbital headaches and ophthalmoplegia. In some patients, THS may occur in parallel with other autoimmune disorders. The underlying etiology of THS remains to be definitively established.
View Article and Find Full Text PDFJ Educ Teach Emerg Med
January 2022
University of California, San Diego, Department of Emergency Medicine, San Diego, CA.
Unlabelled: A 39-year-old previously healthy male presented with three days of right eye pressure and one day of binocular diplopia. He denied history of trauma, headache, or other neurological complaints. He had normal visual acuity, normal intraocular pressure, intact convergence, and no afferent pupillary defect.
View Article and Find Full Text PDFEur J Ophthalmol
May 2023
Microbiology Department, "Giovanni Paolo II" Hospital, Ragusa, ASP 7 Ragusa, Italy.
Purpose: to describe a rare case of orbital apex syndrome caused by aspergillosis with acute presentation.
Case Description: retrospective case report of a 70-year-old man who developed unilateral ophthalmoplegia overnight. He was initially given the diagnosis of suspect Tolosa-Hunt syndrome, but biopsy of the involved tissue showed aspergillosis.
Neurol India
January 2022
Department of Neurology, Nalanda Medical College and Hospital, Patna, Bihar, India.
Ophthalmoplegic migraine (OM) also called recurrent painful ophthalmoplegic neuropathy (RPON) is not a so common disorder. It is characterized by childhood onset, ophthalmoplegia and migraine type of headache. The most common involved nerve is third cranial nerve.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
December 2021
Servicio de Neurología Clínica, Universidad Nacional de Colombia, Bogotá, Colombia; Grupo de investigación en Neurología de la Universidad Nacional de Colombia, NEUOUNAL, Bogotá, Colombia.
Painful ophthalmoplegia syndrome is characterised by the presence of peri-orbital or peri-cranial pain that is accompanied by paralysis of the oculomotor nerves. The differential diagnosis is broad, and requires a rigorous study. Three clinical cases of patients with painful ophthalmoplegia syndrome are described, in which multiple extension studies were required to obtain an aetiological diagnosis.
View Article and Find Full Text PDFJ Neuroophthalmol
December 2021
Departments of Ophthalmology (SV, AC, KD, BK, MS, SK, NM, JW), Rheumatology (JB), Neurology (AC, KD, BK, MS, JW), and Radiology and Imaging Sciences (EQ), University of Utah Hospital, Salt Lake City, Utah.
An 11-year-old boy presented with 2 weeks of intermittent headache, right orbital pain, and constant diplopia. Brain MRI showed dural thickening and enhancement of the right lateral cavernous sinus, right orbital apex, and tentorium. Initial cerebral spinal fluid analysis showed only mild pleocytosis, and serum diagnostics were unrevealing.
View Article and Find Full Text PDFBMJ Case Rep
November 2021
Pediatric Neurology and Neurodevelopmental disorders, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India
Recurrent painful ophthalmoplegic neuropathy (RPON), previously called ophthalmoplegic migraine, is a rare condition characterised by recurrent episodes of headache and ophthalmoplegia. We report a case of 11-year-old girl with recurrent painful ophthalmoplegia due to isolated right oculomotor nerve involvement. MR brain imaging showed enhancing lesion of cisternal segment of right oculomotor nerve.
View Article and Find Full Text PDFN Z Med J
October 2021
University of Otago, Christchurch, New Zealand; Department of Neurology, Canterbury District Health Board, Christchurch, New Zealand.
Here we discuss a presentation of Tolosa-Hunt syndrome (THS) in a 44-year-old female with new right-eye ptosis, ophthalmoplegia and headache. Four days prior, she had almost identical ptosis and ophthalmoplegia in her left eye, which resolved. Cavernous sinus inflammation and symptom improvement with glucocorticoid treatment indicated THS with bilateral eye involvement, a presentation which may be undervalued by the current THS classification.
View Article and Find Full Text PDFEur J Hybrid Imaging
October 2021
Department of Nuclear Medicine, CUB-Hôpital Erasme, Anderlecht, Belgium.
A 73-year-old man with a history of marginal zone lymphoma was admitted to the emergency room for diplopia and ipsilateral headache. The Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) demonstrated intense and symmetrical hypermetabolism of the cavernous sinuses, and hypermetabolic lesions diffusely in the lymph nodes and bones. The diagnosis of high-grade relapse of lymphomatous disease was made.
View Article and Find Full Text PDFPediatr Neurol
December 2021
Department of Pediatrics, National Hospital Organization Beppu Medical Center, Beppu, Oita, Japan. Electronic address:
Acta Neurol Taiwan
March 2021
Department of Ophthalmology, Chi Mei Medical Center, Tainan, Taiwan.
Purpose: Case presentation of newly diagnosed systemic lupus erythematosus (SLE) presenting initially as Tolosa-Hunt syndrome (THS).
Study Design: Retrospective clinical case.
Method: Case report.
Cureus
July 2021
Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, USA.
Coronavirus disease 2019 (COVID-19) infection is associated with a plethora of neurological complications. Newly developed vaccinations targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral spike protein represent a great epidemiological promise with respect to the resolution of the pandemic. However, vaccinations are not without side effects and, in rare cases, have even been implicated in various autoimmune phenomena.
View Article and Find Full Text PDFJNMA J Nepal Med Assoc
July 2021
Department of Neurology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
Tolosa-Hunt Syndrome is a rare disease characterized by painful ophthalmoplegia affecting third, fourth, and/or sixth cranial nerve caused by non-specific inflammation in the cavernous sinus or superior orbital fissure of unknown etiology. We presented a 67-year-old female with Tolosa-Hunt Syndrome. She had a right-sided headache and periorbital pain with double vision.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
September 2021
Research Center of Neurology, Moscow, Russia.
Objective: To study clinical/laboratory signs of primary vasculitis (PV) of the internal carotid artery (ICA) and vertebral artery (VA).
Material And Methods: We examined 31 patients (23 men, 74%, mean age - 36.2±5.
J Curr Ophthalmol
July 2021
Guru Nanak Eye Centre, Department of Ophthalmology, Maulana Azad Medical College, New Delhi, India.
Purpose: To review the diagnostic criteria for Tolosa-Hunt syndrome (THS) and utility of recent modifications.
Methods: We searched PubMed for keywords Tolosa Hunt and magnetic resonance imaging. We compared the three editions of International Classification of Headache Disorders and isolated case reports and case series with the assessment of cavernous internal carotid artery (ICA) caliber to find the prevalence of vascular anomalies.
Tzu Chi Med J
October 2020
Department of Neurology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
The Tolosa-Hunt syndrome (THS) is caused by granulomatous inflammation in the cavernous sinus, superior orbital fissure, or orbit characterized by painful ophthalmoplegia. Here, we report a case of recurrent THS in a 48-year-old female, who initially showed a poor response to low-dose steroids. Each episode involved different cranial nerves and painful ophthalmoplegia.
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