615 results match your criteria: "Tolosa-Hunt Syndrome"

Orthostatic Ocular Neuromyotonia Associated With Recurrent Tolosa-Hunt Syndrome.

J Neuroophthalmol

December 2024

Department of Neurology (HJ), Soonchunhyang University Seoul Hospital, Seoul, South Korea; Department of Neurology (E-SL, J-SL, S-KL), Soonchunhyang University Bucheon Hospital, Bucheon, South Korea; and Department of Neurology (J-SK), Seoul National University Bundang Hospital, Seoul, South Korea.

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Introduction: Tolosa-Hunt syndrome (THS) is a disorder related to inflammation of cavernous sinus and superior orbital fissure that usually presents with ophthalmoplegia and oculomotor nerve palsies. The etiology of the syndrome is unknown and the diagnosis is set by exclusion of other clinical conditions that manifest in a similar way. Intracranial aneurysms, such as intracavernous ones, should be included in the differential diagnosis as they can compress cranial nerves leading to similar clinical presentation.

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Article Synopsis
  • Orbital apex syndrome (OAS) causes visual loss, double vision, and eye pain due to various underlying conditions, including acute invasive fungal rhinosinusitis (AIFRS).
  • A case study presented a 76-year-old man with OAS linked to AIFRS, who underwent surgery and received antifungal treatment after a failed corticosteroid regimen.
  • The findings highlight the difficulty in differentiating between AIFRS-induced OAS and other forms, emphasizing the importance of conducting a biopsy before corticosteroid treatment to avoid worsening fungal infections and ensure better patient outcomes.
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Introduction: Tolosa-Hunt Syndrome (THS) stands as a rare headache disorder distinguished by painful ophthalmoplegia, accompanied by headaches and cranial nerve palsies. The syndrome was initially identified by Eduardo Tolosa in Spain in 1954. He observed granulomatous inflammation surrounding a carotid siphon in a patient with an intracavernous carotid aneurysm.

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This study aims to establish the final definite etiology among patients with long-term follow-up for painful ophthalmoplegia. The data of 44 cases (16 females, 28 females) were examined. In the first diagnosis, subjects were scanned in terms of benign and secondary etiologies.

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A Rare Case of Recurrent Tolosa-Hunt Syndrome With Optic Perineuritis.

J Neuroophthalmol

July 2024

Department of Neurology (BP-S), Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Departments of Ophthalmology (Y-HL) and Neurology (A-CC), Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; and Departments of Ophthalmology (Y-HL) and Neurology (A-CC), School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

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Tolosa-Hunt syndrome (THS), also known as painful ophthalmoplegia, recurrent ophthalmoplegia, or ophthalmoplegia syndrome, is described as severe and unilateral peri-orbital headaches associated with painful and restricted eye movements. THS is an uncommon disorder due to granulomatous inflammation of the cavernous sinus. Although THS is primarily idiopathic, it has rarely been reported in association with systemic lupus erythematosus (SLE).

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Tolosa-Hunt syndrome: a review of diagnostic criteria based on a case series.

Postep Psychiatr Neurol

March 2024

Department of Neurology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Bielański Hospital, Poland.

Purpose: Tolosa-Hunt syndrome (THS) is a rare cause of painful ophtalmoplegia with different clinical manifestations. It is described as a unilateral periorbital headache with concomitant dysfunction of at least one out of the IIIrd, IVth and VIth cranial nerves due to the granulomatous inflammation of periorbital structures, but no underlying cause has been established.

Case Description: We present six patients referred to the Neurology Department due to a unilateral headache with ipsilateral paresis of at least one cranial nerve responsible for eye movements.

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One in a Million: A Woman Presenting with Unilateral Painful Ophthalmoplegia.

Clin Pract Cases Emerg Med

May 2024

Memorial Healthcare System, Department of Emergency Medicine, Hollywood, Florida.

Case Presentation: A 52-year-old female presented to the emergency department with four days of right periorbital pain, ipsilateral temporal headache, diplopia, and photophobia. Physical examination of the right eye revealed painful ophthalmoplegia, cranial nerves III and VI paresis, increased intraocular pressure, and mild proptosis. Magnetic resonance venogram and magnetic resonance imaging orbits with contrast demonstrated an abnormal signal surrounding the right cavernous sinus/petrous apex.

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The article presents a case of idiopathic hypertrophic pachymeningitis of a 61-year-old male patient with severe cephalgia and progressive neuropathy of the oculomotor nerves. The diagnosis was confirmed by MRI with gadolinium, which revealed thickening of the dura mater with accumulation of paramagnetic in the convexital parts of the frontal and temporal regions, as well as on the base of the skull and tentorium. During the use of pulse therapy with glucocorticosteroids (GCS) the symptoms regressed, but when the therapy was stopped, there was a relapse of ptosis and oculomotor abnormalities on the other side followed by a slower effect of GCS therapy.

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Introduction And Importance: Tolosa-Hunt syndrome is a rare condition with unknown aetiology that manifests clinically as unilateral orbital pain and ophthalmoplegia. It is a diagnosis of exclusion that resolves spontaneously but can recur and respond dramatically to systemic steroids.

Case Presentation: The authors herein report a case of a 38-year-old male who presented with horizontal diplopia, limited outward movement of the right eye, and blurry vision for two days which was managed with oral Prednisolone.

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Article Synopsis
  • * The case reported involves a patient with Tolosa-Hunt syndrome, who also showed abducens palsy and tested positive for AQP4 antibodies.
  • * This rare occurrence suggests that there may be a broader clinical connection between NMOSD and Tolosa-Hunt syndrome, highlighting the importance of AQP4 antibody testing in such patients.
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A New Case of Granulomatosis with Polyangiitis Presented with Tolosa-Hunt Syndrome Manifestations.

Case Rep Rheumatol

January 2024

Department of Internal Medicine, School of Medicine, Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Tolosa-Hunt syndrome (THS) is a rare disorder involving the orbital and retro-orbital space. The typical symptoms include sensory loss in the trigeminal nerve's distribution, orbital pain, swelling, headaches, and cranial nerve palsies. .

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Background: Tolosa Hunt Syndrome (THS) was first delineated in 1954 and is caused by a granulomatous inflammation in the cavernous sinus, superior orbital fissure or orbit. In this study the different clinical and diagnostic findings of THS are discussed.

Methods: Case records of patients diagnosed with THS using the International Classification of Headache Disorders 3rd edition criteria from January 2016-July 2022 were considered for the current study.

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Background: Neuromuscular diseases (NMD) emerged as one of the main side effects of the COVID-19 vaccination. We pooled and summarized the evidence on the clinical features and outcomes of NMD associated with COVID-19 vaccination.

Methods: We comprehensively searched three databases, Medline, Embase, and Scopus, using the key terms covering "Neuromuscular disease" AND "COVID-19 vaccine", and pooled the individual patient data extracted from the included studies.

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Review of Tolosa-Hunt Syndrome, Recent Updates.

Curr Pain Headache Rep

December 2023

Division of Neurology, SUNY Upstate Medical University, Syracuse, NY, USA.

Purpose Of Review: We aim to present diagnostic considerations and management insights on Tolosa-Hunt syndrome. We highlight recent controversies in this field and emerging literature.

Recent Findings: The diagnostic categorization of Tolosa-Hunt syndrome remains controversial, with imaging negative cases described in the literature and an increasing literature of secondary causes falsely diagnosed as Tolosa-Hunt syndrome.

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Background: Tolosa-Hunt syndrome (THS) and recurrent painful ophthalmoplegic neuropathy (RPON) are rare diseases reported within the "Painful lesions of the cranial nerves" section of the International Classification of Headache Disorders-3 edition (ICHD-3). In case of a first painful attack, differential diagnosis could be challenging and many pitfalls are due to the rarity of the disorders and the lack of information about correct medical management in youngsters.

Case Presentation: Our main purpose was to report a new case of THS and a new case of RPON describing management and diagnostic investigation at the time of the first episode.

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Tolosa-Hunt syndrome (THS) is an idiopathic inflammatory condition involving the cavernous sinus and orbital apex with an incidence of 1 case per million per year. We report on a case of a 70-year-old male with atypical MRI findings, vision loss, and painless ophthalmoplegia.  Ophthalmic evaluation revealed his best-corrected visual acuity was 20/40 in the right eye and counting fingers at a 0.

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