21,149 results match your criteria: "Tokyo R&D Center[Affiliation]"
J Xenobiot
December 2024
Department of Physics, Faculty of Science, Ibn Tofail University, Kenitra 14000, Morocco.
The Silway River has historically failed to meet safe fecal coliform levels due to improper waste disposal. The river mouth is located in General Santos City, the tuna capital of the Philippines and a leading producer of hogs, cattle, and poultry. The buildup of contaminants due to direct discharge of waste from chicken farms and existing water quality conditions has led to higher fecal matter in the Silway River.
View Article and Find Full Text PDFR Soc Open Sci
September 2024
Centre for Neuroscience in Education, University of Cambridge, Cambridge, UK.
French and German poetry are classically considered to utilize fundamentally different linguistic structures to create rhythmic regularity. Their metrical rhythm structures are considered poetically to be very different. However, the biophysical and neurophysiological constraints upon the speakers of these poems are highly similar.
View Article and Find Full Text PDFJ Appl Physiol (1985)
December 2024
School of Health Science, Sapporo Medical University, Sapporo, Japan.
Peripheral endothelial function, which accounts for the variability in shear stimulus, can be assessed using shear-mediated dilation normalized to the increased shear stimulus. Similarly, shear-mediated dilation of the internal carotid artery (ICA), an index of cerebrovascular endothelial function, should be normalized to increased shear stimulus. However, this approach has not yet been validated.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Laboratory for Chemistry and Life Sciences, Tokyo Institute of Technology, Yokohama, Kanagawa, 226-8501, Japan.
Nanostructured Pt-based catalysts have attracted considerable attention for fuel-cell applications. This study introduces a novel one-pot and low-temperature polyol approach for synthesizing support-free, connected nanoparticles with non-Pt metal cores and Pt shells. Unlike conventional heat treatment methods, the developed support-free and Fe-free connected Pd@Pt (Pd@Pt) nanoparticle catalyst possesses a stable nanonetwork structure with a high surface area.
View Article and Find Full Text PDFACS Nano
December 2024
Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.
The intrinsic temperature dependence of Raman-active modes in carbon nanotubes (CNTs), particularly the radial breathing mode (RBM), has been a topic of a long-standing controversy. In this study, we prepared suspended individual CNTs to investigate how their Raman spectra depend on temperature and to understand the effects of environmental conditions on this dependency. We analyzed the intrinsic temperature dependence of the main Raman-active modes, including the RBM, the moiré-activated R feature, and the G-band in double-walled carbon nanotubes (DWCNT) and single-walled carbon nanotubes (SWCNTs) after complete desorption of air.
View Article and Find Full Text PDFJ Neuroeng Rehabil
December 2024
Department of Rehabilitation Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Background: Arm-lifting movements (shoulder flexion) are essential for upper extremity rehabilitation after a stroke. Abnormal flexor synergy (elbow flexion) is frequently observed during shoulder flexion, impeding functional improvement. However, no quantitative method exists for assessing abnormal flexor synergy.
View Article and Find Full Text PDFJ Phys Chem B
December 2024
Graduate School of Integrated Sciences for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Hiroshima, Japan.
We investigated oscillatory motion of a camphor disk floating on water containing 5 mM hexylethylenediaminium trifluoroacetate (HHexen-TFA) as an ionic liquid (IL). The frequency of the oscillatory motion increased with increasing concentrations of the transition metal ions Cu and Ni but was insensitive to Na, Ca, and Mg, the typical metal ions in the water phase. The surface tension of the water phase containing 5 mM HHexen-TFA also increased with increasing concentrations of Cu and Ni but was insensitive to Na, Ca, and Mg.
View Article and Find Full Text PDFBiosci Biotechnol Biochem
December 2024
R&D Division, Meiji Co., Ltd., 1-29-1 Nanakuni, Hachioji, Tokyo 192-0919, Japan.
It is essential to remove cholesterol from the body to suppress atherosclerosis progression. ABCA1 and ABCG1 transport cholesterol in peripheral cells including macrophages and function in the formation of high-density lipoprotein (HDL). ABCG5/ABCG8 functions in the efflux of cholesterol from the body.
View Article and Find Full Text PDFCancer Chemother Pharmacol
December 2024
Division of Pharmacotherapeutics, Department of Clinical Pharmacy, School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Purpose: The blood concentrations of some tyrosine kinase inhibitors are known to decrease with long-term administration. We evaluated the variability in the serum concentrations of sunitinib and its metabolites in patients receiving long-term sunitinib treatment.
Methods: This study prospectively recruited patients who received sunitinib for metastatic renal cell carcinoma at the Showa University Hospital between March 2020 and January 2022.
Transl Vis Sci Technol
December 2024
Kawasaki-Tama Eye Clinic, Kawasaki, Kanagawa, Japan.
Purpose: The purpose of this study was to investigate the dynamic changes in aqueous concentrations of angiopoietin (Ang)-1/2 and vascular endothelial growth factor (VEGF) during injection in treatment-naïve patients with diabetic macular edema (DME) receiving faricimab during the induction phase (3 consecutive monthly doses) and retrospectively analyze the data.
Methods: Thirty-five eyes of 26 patients (age = 63.1 ± 12.
Nat Chem Biol
January 2025
CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
J Sports Sci
December 2024
Faculty of Sports and Budo Coaching Studies, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan.
This study aimed to comprehensively demonstrate support leg joint kinetic determinants of maximal speed sprint performance. Ground reaction forces and marker coordinates attached to the body were measured in the maximal speed phase from 44 male sprinters. Then, three-dimensional leg joint torque, angular velocity and power were calculated.
View Article and Find Full Text PDFGeriatr Gerontol Int
December 2024
Department of Home and Palliative Care Nursing, Graduate School of Health Care Sciences, Institute of Science Tokyo, Tokyo, Japan.
This study examined the relationship between Long-Term Care Insurance care need levels and Barthel Index scores in Japanese nursing home residents. Findings show a strong correlation (r = -0.68), comparable to community-dwelling individuals, yet certain care need levels exhibited large score variability.
View Article and Find Full Text PDFNature
December 2024
State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
NPJ Sci Food
December 2024
Institute of Advanced Biomedical Engineering and Sciences, TWIns, Tokyo Women's Medical University, Tokyo, Japan.
To establish a sustainable cultured meat technology, a low-cost culture medium must be developed without expensive biological materials such as serum and coating substances. However, even adhering bovine myogenic cells to uncoated culture dishes in the serum-free medium is challenging. We found that serum-free culture medium conditioned by HepG2 and NIH/3T3 cells not only accomplished the cell adhesion on uncoated culture dishes (the serum-containing medium : the serum-free medium : the conditioned medium = 6722 ± 1500 : 2210 ± 319 : 5985 ± 1558 cells/cm), but also induced proliferation comparable to that observed in a serum-containing medium (the serum-containing medium : the serum-free medium : the conditioned medium = 10,050 ± 2814 : 2200 ± 707 : 8998 ± 3890 cells/cm).
View Article and Find Full Text PDFAnal Sci
December 2024
School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo, 192-0982, Japan.
A biosensor for biochemical oxygen demand (BOD) was developed based on intracellular 5'-adenosine triphosphate (ATP) measurements in Saccharomyces cerevisiae. Intracellular ATP was measured using an engineered protein named ATeam, comprising a bacterial FF-ATP synthase ε subunit sandwiched between cyan fluorescent protein and mVenus, a modified yellow fluorescent protein. Because the binding of ATP to ATeam induces changes in the fluorescence spectra owing to Fӧrster resonance energy transfer, S.
View Article and Find Full Text PDFWien Klin Wochenschr
December 2024
Department of Rehabilitation Medicine, Mie University Graduate School of Medicine, Mie, Japan.
Objective: The potential link between malnutrition and dysphagia along with its underlying mechanisms remains unknown. This study aimed to investigate the association between malnutrition factors and dysphagia mediated by a decline in activities of daily living (ADL) among nursing home residents.
Methods: This cross-sectional study used data from 705 nursing home residents.
ACS Nanosci Au
December 2024
Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551, Japan.
The dynamic control of chiral (enantiomeric) responses in chiral host-guest complexes through external stimuli is a significant challenge in modern chemistry for developing smart stimuli-responsive materials. Herein, we report the (chir)optical properties and chiral recognition behavior of water-soluble chiral naphthotubes () under the influence of hydrostatic pressure as an external stimulus. The hydrostatic pressure spectral profiles compared to those obtained at normal pressure revealed the dynamic behavior of under hydrostatic pressure, owing to the flexible linker.
View Article and Find Full Text PDFPCN Rep
December 2024
Department of Medicine, Division of Neurology, Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.
Aim: This study aimed to develop and validate a Japanese version of the Public Attitudes Toward Epilepsy (PATE-J) Scale to measure attitudes towards epilepsy among the general Japanese population.
Methods: The study employed a cross-sectional design using an online survey of 537 participants from the general public in Japan, with follow-up surveys at 2 weeks and 3 months. The PATE Scale was translated following standard guidelines and validated by conducting confirmatory factor analysis (CFA) on the complete data set to assess the original two-factor structure of the PATE Scale.
J Infect Chemother
December 2024
Pfizer R&D Japan, Tokyo, Japan. Electronic address:
Background: This phase 3 open-label study evaluated the efficacy and safety of ceftazidime-avibactam in Japanese patients with complicated intra-abdominal infections (cIAIs).
Methods: Hospitalised adults with cIAI received ceftazidime-avibactam + metronidazole for 5-14 days. The primary efficacy endpoint was clinical cure at the test-of-cure (TOC) visit in the clinically evaluable (CE) analysis set.
Clin Physiol Funct Imaging
January 2025
Research Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya, Japan.
The present study examined the relationships between trunk tissue distribution, metabolic risk factors, and physical performance in young Japanese individuals using cross-sectional and longitudinal analyses. Thirty-six healthy Japanese men (n = 20, body mass index [BMI]: 20.8 ± 2.
View Article and Find Full Text PDFSci Data
December 2024
University of Oslo, Department of Geosciences, Oslo, 0313, Norway.
Sea ice is a key element of the global Earth system, with a major impact on global climate and regional weather. Unfortunately, accurate sea ice modeling is challenging due to the diversity and complexity of underlying physics happening there, and a relative lack of ground truth observations. This is especially true for the Marginal Ice Zone (MIZ), which is the area where sea ice is affected by incoming ocean waves.
View Article and Find Full Text PDFJ Strength Cond Res
December 2024
Faculty of Sports and Life Science, National Institute of Fitness and Sports in Kanoya, Kanoya, Kagoshima, Japan.
Chiba, Y, Sato, K, Yoshimoto, T, Ohnuma, H, Yamanaka, R, Takahashi, K, Kobayashi, K, Matsubayashi, T, and Takai, Y. Revamping pace distribution: A case study on elevating the men's 400 m track and field Japanese national record after 32 years. J Strength Cond Res XX(X): 000-000, 2024-Many studies have investigated the 400-m sprint, and the optimal pacing strategy is subject to debate.
View Article and Find Full Text PDFClin Biomech (Bristol)
December 2024
Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan; Global Nursing Research Center, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan. Electronic address:
Background: Pressure injury prevention is important in older patients with immobility. This requires an accurate and efficient prediction of the development of pressure injuries. We aimed to develop a method for estimating skin temperature changes due to ischemia and inflammation using temperature sensors placed under bedsheets to provide an objective, non-invasive, and non-constrained risk assessment tool.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
Graduate School of Science and Engineering, Soka University, Tokyo, 192-8577, Japan.
Numerous studies indicate biochar's nitrogen (N) adsorption capacity plays a crucial role in soil N retention. However, there is limited understanding on inorganic N adsorption mechanisms in biochar derived from aquatic weeds such as water hyacinth (WH). This study investigated ammonium-N (NH-N) and nitrate-N (NO-N) adsorption capacities and mechanisms of WH biochar pyrolyzed at different pyrolysis temperatures of 400 °C, 600 °C, and 800 °C (BC400, BC600, and BC800, respectively).
View Article and Find Full Text PDF