78 results match your criteria: "Tokyo Metropolitan Toshima Hospital.[Affiliation]"

Torticollis in incomplete Kawasaki disease: a case of atlantoaxial rotatory fixation.

BJR Case Rep

November 2024

Department of Orthopaedic Surgery, Tokyo Metropolitan Toshima Hospital, Tokyo 173-0015, Japan.

Various respiratory, musculoskeletal, gastrointestinal, neurological, and urinary complications have been reported in Kawasaki disease. Here, we describe a rare case of atlantoaxial rotatory fixation (AARF) associated with incomplete Kawasaki disease. The case is of a healthy 4-year-old Japanese boy who had a high-grade fever, lymphadenopathy, and torticollis diagnosed with incomplete Kawasaki disease.

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Introduction: Recently, researchers have introduced the concept of 'early term' infants, defined as infants born at 37 or 38 weeks of gestation, and their outcome has been discussed. Although the complications experienced by early term are less severe than those in preterm infants, this group accounts for a much larger proportion of newborns, making the assessment of outcomes important in clinical practice.

Methods: This observational study of term infants born at Tokyo Metropolitan Toshima Hospital aimed to understand the short-term outcomes in early term infants.

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Article Synopsis
  • Thromboembolism is a critical concern in patients undergoing endovascular treatment for ruptured cerebral aneurysms, and administering antiplatelet agents like aspirin before the procedure may lower this risk.
  • The study, called ASTOP, is a multicenter, randomized, double-blind trial involving 484 patients, comparing the effects of 200 mg of aspirin versus a placebo prior to treatment.
  • Primary outcomes will focus on measuring thromboembolic complications and ischemic lesions during the procedure, while secondary outcomes will assess cerebral ischemic events, bleeding incidents, and patient functional status after 90 days.
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The COVID-19 pandemic has impacted the epidemiology of other infectious diseases. In particular, the respiratory syncytial (RS) virus infects almost all children during their first or second year of life. However, during the COVID-19 pandemic, many restrictions were enforced that isolated children from other children.

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Article Synopsis
  • - Anamorelin is an oral drug designed to treat cancer cachexia, a condition often seen in cancer patients, and it interacts with the liver enzyme CYP3A4, which can lead to drug-drug interactions.
  • - The study developed a high-performance liquid chromatography-ultraviolet (HPLC-UV) method to measure anamorelin levels in human plasma, focusing on sample preparation and accurate separation using specific chemical conditions.
  • - The method showed a strong calibration curve and good precision and accuracy, suggesting it could be effectively used in clinical settings to monitor anamorelin concentration.
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Purpose: To compare different biopsy systems with different-sized needles by determining the weight of the tissue cores, which is one of the important factors for precise pathological diagnoses, and to provide a rationale for choosing the appropriate breast biopsy system with the appropriate needle for breast cancer biopsy.

Methods: Six different vacuum-assisted biopsy (VAB) systems and one core needle biopsy (CNB) system with different-sized needles in different modes were compared, representing 15 total combinations. Tissue cores were obtained from a chicken breast phantom, which is a common substitute for human breast tissue.

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Background And Objectives: Although intraprocedural rupture (IPR) is rare, it is a devastating complication of endovascular treatment (EVT) for intracranial aneurysms. Very few studies have been conducted on IPR, and the safety and efficacy of management techniques of IPR have not been investigated.

Methods: Patients who experienced IPR during EVT between 2013 and 2022 were enrolled from a multicenter observational registry.

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Here, we report the complete genome sequences of strains 473AN and 473GN, isolated from the blood culture of a Japanese patient with infective endocarditis. The complete genomes of 473AN and 473GN consist of single chromosomes of 2,065,772 and 2,094,461 bp, respectively.

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The Effects of Low Concentrations of Pravastatin on Placental Cells.

Reprod Sci

October 2024

Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

Pravastatin is a promising medication to treat preeclampsia. However, the appropriate dose of pravastatin for managing preeclampsia has not been established. In this in vitro study, we examined the effects of low concentrations of pravastatin (0.

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Contact aspiration for basilar artery occlusion safely reduces the puncture-to-recanalization time.

Clin Neurol Neurosurg

July 2024

Department of Endovascular Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address:

Article Synopsis
  • This study investigates the effectiveness of first-line contact aspiration compared to other treatment strategies for basilar artery occlusion in endovascular thrombectomy.
  • A total of 84 patients from 16 Japanese stroke centers were analyzed, with findings showing no significant differences in recanalization rates but indicating contact aspiration led to faster results.
  • The results suggest that while contact aspiration gives better functional outcomes, the main advantage is a significantly shorter time from puncture to successful recanalization.
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Typically, non-typhoidal (NTS) causes gastroenteritis; however, NTS can also lead to extraintestinal manifestations like bacteremia, meningitis, and abscess in vulnerable populations such as children, elderly, and immunocompromised individuals. Extraintestinal manifestations in an immunocompetent patient are uncommon. Here, we report a case of iliacus myositis and bacteremia caused by NTS in a healthy adult.

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Human mpox presenting with penile edema and ulcer: A case report.

J Infect Chemother

August 2024

Department of Infectious Diseases, Tokyo Metropolitan Toshima Hospital, Tokyo, Japan.

Human mpox, which has spread worldwide since May 2022, is characterized by symptoms involving the genital area; however, its treatment methods and clinical course are not completely understood. Furthermore, penile swelling in human mpox can be difficult to differentiate from cellulitis and antibiotic use has been reported in such cases. Herein, we report a case of human mpox in Japan with prominent penile swelling and persistent penile ulcers that improved without specific treatment.

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Infectious virus shedding from individuals infected with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is used to estimate human-to-human transmission risk. Control of SARS-CoV-2 transmission requires identifying the immune correlates that protect infectious virus shedding. Mucosal immunity prevents infection by SARS-CoV-2, which replicates in the respiratory epithelium and spreads rapidly to other hosts.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variants are now a pandemic. There are differences in clinical features in SARS-CoV-2 variants and we conducted this study to assess the clinical features of coronavirus disease (COVID-19) in children with SARS-CoV-2 omicron variants. The study included children with COVID-19 arrivedto Tokyo Metropolitan Toshima Hospital between January 2020 and October 2022.

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Background: Exercise therapy is the key to preventing admission of patients with type 2 diabetes mellitus (T2DM). However, a few studies have examined the effects of exercise therapy on patients with T2DM undergoing inpatient diabetes self-management education and support (IDSMES).

Objective: This study investigated whether exercise therapy influenced the incidence of admission after discharge in patients with T2DM undergoing IDSMES.

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Objective: The association between the severity of COVID-19 and gastrointestinal (GI) bleeding is unknown. This study aimed to determine whether the severity of COVID-19 is a risk factor for GI bleeding.

Design: A multicentre, retrospective cohort study was conducted on hospitalised patients with COVID-19 between January 2020 and December 2021.

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Aim: The head circumference to chest circumference (HC/CC) ratio has been used to identify low birth weight infants in developed countries. This study was conducted to examine whether the ratio could distinguish asymmetrical foetal growth restriction (FGR).

Methods: This retrospective observational study was conducted with 1955 infants (50.

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Background: A left atrial posterior wall isolation (LAPWI) is one of the atrial fibrillation (AF) ablation strategies.

Hypothesis: We hypothesized that an additional empirical LAPWI would increase the freedom from recurrent atrial arrhythmias as compared to standard AF ablation in persistent AF patients.

Methods: The CORNERSTONE AF study is a prospective, randomized, multicenter study investigating patients with AF persisting for >7 days and <3 years undergoing first-time AF ablation.

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Article Synopsis
  • The study aimed to explore how baseline infarct area and collateral status affect clinical outcomes in stroke patients with acute basilar artery occlusion after undergoing endovascular treatment.
  • It analyzed 86 patients treated within 24 hours, finding that those with a higher baseline infarct score (pc-ASPECTS ≥ 7) had better chances of recovery, with 43% achieving good outcomes.
  • It concluded that while pc-ASPECTS is a reliable predictor of positive clinical outcomes after treatment, the collateral status scores did not show a significant impact.
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Retiform hemangioendothelioma of the breast in a man with F-flurodeoxyglucose accumulation on positron emission tomography: a case report.

Surg Case Rep

April 2023

Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo, 113-8677, Japan.

Background: Retiform hemangioendothelioma (RH) is a rare, intermediate-grade vascular tumor that often arises in the trunk and extremities. The clinical and radiological features of RH remain largely unknown.

Case Presentation: A male patient in his 70s presented with shortness of breath on exertion, and computed tomography incidentally revealed a tumor in his right breast.

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Article Synopsis
  • The study aimed to determine if SARS-CoV-2 infection leads to acute encephalopathy in children and to identify the prevalent syndromes and their outcomes among pediatric patients in Japan from January 2020 to May 2022.
  • A nationwide survey of the Japanese Society of Child Neurology found 31 eligible patients, with common diagnoses being biphasic seizures and cases linked to multisystem inflammatory syndrome in children (MIS-C).
  • Out of the 31 patients studied, 29% experienced severe outcomes or died, highlighting the seriousness of encephalopathy associated with severe COVID-19 symptoms.
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Objective/aim: We aimed to demonstrate the anatomical relationship between the recurrent laryngeal nerves (RLNs), thin membranous dense connective tissue (TMDCT [e.g., the visceral or vascular sheaths around the esophagus]), and the lymph nodes around the esophagus at the curving portion of the RLNs for rational and efficient lymph node dissection.

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