Amebic liver abscess in an elderly AIDS patient.

An elderly bisexual male AIDS patient, whose CD4 cell count was 128/mm3 and HIV-RNA was 3.0x10(5) copies/ml, was admitted because of amebic liver abscess and poor nutritional condition. He was treated with daily doses of 1,500 mg of metronidazole for 14 days for amebic liver abscess and with anti-HIV drugs; good therapeutic results were observed.

Acute cerebellar ataxia of a patient with SLE.

We described a 28-year-old woman with systemic lupus erythematosus (SLE) presented with digestive tract, skin and renal symptoms and afterwards developed acute cerebellar ataxia, a paresis of the right inferior rectus muscle, left abducens paralysis and left facial palsy which seemed to be consistent with a brainstem lesion visible on magnetic resonance imaging (MRI). This lesion disappeared within 9 days of corticosteroid treatment. It is suggested that this lesion is focal edema induced by acute changes in the blood brain barrier secondary to a vasculopathy.

Serum levels of thrombomodulin, intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin in the acute phase of Plasmodium vivax malaria.

Elevated plasma or serum levels of thrombomodulin (TM), intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin have been reported in several diseases. However, plasma or serum levels of TM, ICAM-1, VCAM-1, and E-selectin have not been investigated in the acute phase of Plasmodium vivax malaria. Serum TM, ICAM-1, VCAM-1, E-selectin, and creatinine levels were determined in six Japanese patients in the acute phase of vivax malaria and in seven healthy Japanese controls.

Serum thrombomodulin levels in patients with typhoid fever.

Elevated plasma or serum levels of thrombomodulin (TM) have been reported in some diseases. However, to our knowledge, plasma and serum levels of TM have not been investigated in febrile patients with typhoid fever. Serum TM and creatinine levels were determined in 7 male Japanese febrile patients with typhoid fever and 6 male Japanese healthy controls.

[A girl with transient psychological disturbance caused by orally administered acyclovir--differentiation between acyclovir neurotoxicity and herpes simplex encephalitis].

A previously healthy 7-year-old girl suffered from oral herpetic gingivostomatitis. After four days, oral administration of acyclovir (ACV), 1,000 mg in five divided doses, was started. She became irritable and intermittently delirious next day.

Present characteristics of symptomatic amebiasis due to Entamoeba histolytica in the east-southeast area of Tokyo.

Admitted medical records, from January 1988 to December 1995, of 28 symptomatic amebic patients who lived in the east-southeast area of Tokyo were studied retrospectively, in order to find the present characteristics of symptomatic amebiasis due to Entamoeba histolytica in this area. Categorized by disease, there were 14 cases of colitis, 9 cases of liver abscess, 4 cases of colitis with liver abscess, and 1 case of liver abscess with brain abscess. Patients consisted of 26 Japanese males, 0 Japanese females, 1 non-Japanese male and 1 non-Japanese female.

[Localized lesions on MRI in the globus pallidus, subthalamic nuclei and hippocampus in patients with severe intellectual and motor disabilities].

We examined the clinical picture of eight patients with severe intellectual and motor disabilities, who had experienced prolonged and severe neonatal jaundice, and showed localized lesions in the globus pallidus, subthalamic nuclei and hippocampus on MRI. All patients had athetoid tetraplegia, and five patients showed disturbed ocular movements and seven showed dysphagia. Five patients could communicate with others or utter words, and all showed mental retardation.

Epidemiologic features of domestically contracted shigellosis in a Tokyo Metropolitan Hospital.

Sixty-nine Japanese patients infected with shigellosis domestically were admitted to a hospital in eastern Tokyo from January 1988 to December 1995. According to a review of their charts 92% of these patients lived in Tokyo, and 88% contracted the disease in Tokyo. Sixty-eight percent and 29% of them were infected withShigella sonnei and S.

Treatment of symptomatic amebic colitis in human immunodeficiency virus-infected persons.

While most Entamoeba histolytica appearing in male homosexuals infected with human immunodeficiency virus (HIV) is considered non-invasive in Western countries, and treatment of amebiasis in these persons has received very little attention, in Japan some male homosexual amebiasis patients infected with HIV complain of symptoms attributable to E. histolytica infection. We investigated whether symptomatic E histolytica amebic colitis in HIV-infected persons requires higher doses or longer duration of antiamebic drug therapy than in non HIV-infected patients.

Schistosoma mansoni infestation: an imported case of a Japanese patient.

A 25-year-old male Japanese who had resided in Ethiopia, presented to our department with eosinophilia, which had been present for about 1 year. Stool examination revealed eggs of Schistosoma mansoni containing miracidia with flame cell activity, and he was diagnosed as having an infestation with this organism. He was treated with praziquantel, and a good parasitological therapeutic result was obtained.

Malaria--eight years of experience in a Tokyo metropolitan hospital.

Malaria patients who were admitted to the Department of Infectious Diseases of the Tokyo Metropolitan Bokutoh General Hospital during the past 8 years are reviewed. Cases included 17 patients infected with Plasmodium falciparum (14 Japanese), 13 patients infected with P. vivax (9 Japanese), 3 patients infected with P.

Therapeutic Effect of Fluoroquinolones against Shigellosis Patients Coinfected with Giardia lamblia.

This study examined whether coinfection of shigellosis patients with Giardia lamblia had any influence on the bacterial therapeutic effect of fluoroquinolones. Five shigellosis patients with a coinfection with G. lamblia and 15 control patients with shigellosis only were treated with standard doses of fluoroquinolones.

[Two cases of catheter tip dislocation to the duodenal bulb: a rare complication of hepatic arterial infusion chemotherapy].

Case 1: A 63-year-old woman underwent transverse colectomy and hepatectomy for colonic cancer and liver metastasis. A hepatic arterial infusion port (HAIP) was implanted. Continuous infusion of 5-FU (total amount, 7,500 mg) caused a hemorrhagic duodenal ulcer 15 months after.

Possible formation of new brood capsule by the previously formed brood capsule in Echinococcus multilocularis metacestodes.

In Echinococcus multilocularis metacestodes obtained from the peritoneal cavity of an experimentally infected jird, cellular accumulations were found not only on the inner surfaces of germinal layers but also on the outer surfaces of brood capsules. These cellular accumulations are believed to represent at incipient form of the brood capsule. It has been thought that brood capsules are produced by the germinal layer, but we speculate that the brood capsule itself, as well as the germinal layer, may have the potential to produce new brood capsules.

Brain abscess due to infection with Entamoeba histolytica.

We successfully treated a serious case of Entamoeba histolytica infection showing brain abscess, meningitis, and liver abscess by oral administration of metronidazole, intramuscular injection of dehydroemetine, and drainage of the brain abscess. The diagnosis of amebic brain abscess was based on a combination of clinical symptoms and signs, computed tomography and magnetic resonance imaging findings, a positive serologic test result for E. histolytica, a dramatic response to anti-amebic drugs after an ineffective therapeutic history with antibacterial drugs, and application of the polymerase chain reaction method.

Symptomatic amebic colitis in a Japanese homosexual AIDS patient.

A 30-year-old Japanese homosexual AIDS patient was admitted to hospital because of Kaposi's sarcoma and mild diarrhea on February 4, 1993. Mud-like stool with blood and mucous was recognized after admission. Although serologic tests for Entamoeba histolytica were negative, trophozoites of E.

Cerebral cysticercosis.

A 44-year-old female underwent a right frontal craniotomy under a diagnosis of metastatic brain tumor and a fluid-filled cystic lesion was extirpated. One rice grain sized nodule was identified in the cyst and histopathological examination of the nodule showed a scolex with hooks and suckers. These macro and microscopic findings indicated a diagnosis of cerebral cysticercosis, caused by infection of the larval stage of some type of Taenia species.