121 results match your criteria: "Tokyo Medical University Tokyo Japan.[Affiliation]"
Purpose: This descriptive analysis evaluated the 2022 assisted reproductive technology (ART) data collected by the Japan Society of Obstetrics and Gynecology registry.
Methods And Results: In 2022 (cutoff date 30 November 2023), 634 of 635 registered ART facilities participated; 602 implemented ART treatment, with 543 630 registered cycles and 77 206 neonates (9.1% and 10.
Aim: To develop a trauma surgery training program using porcine organs and evaluate its usefulness. This program allows participants to experience the tactile sensation of organs and bleeding, which are impossible in trauma surgery training using a cadaver.
Methods: Resected organs (heart, lung, liver, spleen, kidney, small intestine, bladder, and external carotid artery) from slaughtered pigs for medical research were perfused with saline solution, flash-frozen in a deep freezer, and thawed naturally on the morning of training.
Article Synopsis
- The study explores how childhood nurturing experiences impact adult depression through subjective social status and personality traits, specifically neuroticism.
- It involved a survey of 404 adults and used statistical analyses to show that both nurturing and subject social status influence neuroticism, which in turn affects depressive symptoms.
- Findings suggest that understanding these relationships may help clarify the origins of depression and how early life experiences shape mental health in adulthood.
Article Synopsis
- Replacing a lumen-apposing metal stent (LAMS) with a double-pigtail plastic stent (DPS) is effective for preventing recurrence of walled-off necrosis, but traditional success rates are low; so a new technique was developed.
- In the new method, a 7-F DPS is placed inside the LAMS to facilitate its removal while allowing granulation to occur, which stabilizes the DPS; out of 18 patients, 17 had successful replacements with no recurrences observed over 385 days.
- Prior to this technique, replacing LAMS with DPS had a low success rate (61.8%), and recurrence of pancreatic fluid collection was noted in 15.3% of patients who could
Article Synopsis
- The study aimed to compare two types of major depressive disorder: anxious distress (ANXD) and melancholic features (MEL), focusing on psychomotor disturbances like agitation and retardation.
- A total of 106 patients were assessed using the CORE measure, and logistic analysis showed that lower retardation scores were linked to ANXD diagnoses, while higher agitation scores were associated with both ANXD and MEL.
- The findings suggest that while ANXD and MEL can share agitation, they differ in terms of psychomotor retardation and noninteractiveness, indicating a potential overlap in how these disorders are defined.
Article Synopsis
- The study aimed to promote sustainable practices in endoscopy by examining how gowning techniques impact microbial contamination and carbon emissions, assessing the potential for reducing medical waste.* -
- Involving 25 patients, researchers found a 56% contamination rate across isolation gowns, with higher rates among resident endoscopists compared to experts, particularly noting increased bacteria on the left arm of gowns.* -
- The bacteria found were non-pathogenic, suggesting that complete changes of protective gear may not be necessary, supporting the initiative for "green endoscopy" to enhance sustainability in medical practices.*
From Optional to Default - Enhancing Article Viewership Through X (Formerly Twitter) Posting.
Circ Rep
September 2024
Information and Communication Committee, the Japanese Circulation Society Tokyo Japan.
Article Synopsis
- * Researchers analyzed X-posting rates and journal viewership data from April 2022 to September 2023, noting a significant increase in both after protocol changes made in March 2023.
- * The findings suggested that adopting the new X-posting strategy led to more article views, indicating a positive impact on viewer access.
Effects of the COVID-19 pandemic on short-term postoperative outcomes of emergency surgery for gastroduodenal perforation: A nationwide study in Japan based on the National Clinical Database.
Ann Gastroenterol Surg
September 2024
The Japan Surgical Society Tokyo Japan.
Article Synopsis
- * Analyzed data from nearly 8,000 cases between 2019 and 2021 showed only minor increases in mortality and complications, with one significant spike in complications in July 2020.
- * Overall, the pandemic had limited negative impacts on surgical outcomes, indicating that Japan's emergency surgical system for gastroduodenal perforation remained effective throughout this period.
Is multidisciplinary treatment effective for invasive intraductal papillary mucinous carcinoma?
Ann Gastroenterol Surg
September 2024
Second Department of Surgery Wakayama Medical University, School of Medicine Wakayama Japan.
Article Synopsis
- * Analyzing data from 1183 patients, it found that completing 6 months of postoperative adjuvant therapy significantly improved overall, disease-specific, and recurrence-free survival, especially for high-risk patients.
- * Additionally, neoadjuvant therapy showed benefits for those with borderline resectable IPMC, and any treatment for recurrence after surgery was linked to longer survival compared to no treatment.
Aim: Various factors are thought to be involved in the development of depression, but the mechanisms are not yet clear. Although several reports have demonstrated that parental attitude experienced in childhood, depressive rumination, and sleep disturbances each influence depressive symptoms, and the association between two of these four variables, to our knowledge, no reports to date have investigated the association among the four variables.
Methods: A questionnaire survey was administered to 576 adults who agreed to participate in this study between April 2017 and April 2018.
Aim: The aim of this study was to investigate the association of psychological and chronobiological factors with the presence and severity of chronic insomnia by symptom subtypes and their impacts on daytime dysfunctions.
Methods: Participants of the present web-based epidemiological study were classified as follows: difficulty initiating sleep (DIS) ( = 91); difficulty maintaining sleep (DMS) ( = 13); early morning awakening (EMA) ( = 48); DIS + DMS ( = 67); DIS + EMA ( = 23); DMS + EMA ( = 24); triplet of DIS, DMS, and EMA symptoms (TRP) ( = 69); and normal sleepers ( = 4590). The Insomnia Severity Index (ISI), Hospital Anxiety and Depression Scale (HADS), Munich Chronotype Questionnaire (MCTQ), insomnia-related psychological measures (including the Ford Insomnia Response to Stress Test [FIRST] and the Dysfunctional Beliefs and Attitudes about Sleep Scale [DBAS]), and the cognitive and somatic domains of the Pre-Sleep Arousal Scale (PSAS) were evaluated.
Aim: The association of parenting experiences in childhood with anxiety symptoms in adulthood has yet to be clarified. We hypothesized that interpersonal sensitivity (IPS) mediates the impacts of parenting experiences in childhood on anxiety symptoms and negative assessment of life events in adulthood.
Methods: An observational cross-sectional study was carried out from January 2014 to August 2014 on 853 adults.
Aim: Hyperthymic temperament is a cheerful action orientation that is suggested to have a protective effect on depressive symptoms. We recently reported that hyperthymic temperament can positively predict activation of reward-related brain areas in anticipation of monetary rewards, which could serve as a biomarker of hyperthymic temperament. However, the relationship between hyperthymic temperament and neural responsiveness to nonmonetary rewards (i.
View Article and Find Full Text PDFAim: Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients.
Methods: A retrospective matched case-control study was conducted on adult patients admitted to every department of Tokyo Medical University Hospital, with the outcome being in-hospital falls.
Article Synopsis
- The text discusses a previously underestimated pathogen that is part of normal skin flora but is now recognized for causing severe infections, especially in immunocompromised patients.
- Identifying this pathogen at the species level poses challenges in clinical microbiology, which limits understanding of its role in infectious diseases.
- A rare case study is presented involving a patient with severe neutropenia who developed multiple subcutaneous abscesses, with the pathogen identified through genotyping, emphasizing its significance in severe skin infections.
Background: The current Japanese hypertension management guidelines (2019) recommend regular exercise for all patients with hypertension. However, limited evidence is available regarding the prevalence of exercise habits in these patients. Therefore, we examined the proportion of participants who met the recommendations on exercise in the Japanese hypertension management guidelines (2019) using a nationally representative sample.
View Article and Find Full Text PDFEffects of the COVID-19 pandemic on short-term postoperative outcomes for colorectal perforation: A nationwide study in Japan based on the National Clinical Database.
Ann Gastroenterol Surg
May 2024
The Japan Surgical Society Tokyo Japan.
Aim: Possible negative effects of the COVID-19 pandemic on short-term postoperative outcomes for colorectal perforation in Japan were examined in this study.
Methods: The National Clinical Database (NCD) is a large-scale database including more than 95% of surgical cases in Japan. We analyzed 13 107 cases of colorectal perforation from 2019 to 2021.
Article Synopsis
- IgA pemphigus is an autoimmune disease characterized by the presence of IgA autoantibodies targeting keratinocyte cell surfaces, resulting in skin and, rarely, oral mucosal lesions.
- A 31-year-old woman exhibited skin erythema, pustules, and erosions in her mouth, with histopathology confirming acantholysis and neutrophil infiltration.
- While typical cases of IgA pemphigus have limited oral involvement, this case highlights the presence of oral lesions as a potential indicator of anti-desmoglein 3 IgA, suggesting a rare subtype of the disease.
Background: Several reports on organ injury and death due to incorrect chest tube insertion exist; however, reports on the chest tube penetrating the liver and reaching the inferior vena cava are limited.
Case Presentation: A 79-year-old man presented with a clamped tube because of massive bleeding from the tube following right chest tube replacement in the hospital of origin. The tube entered the inferior vena cava from the hepatic parenchyma via the right hepatic vein and was removed 15 h later because his hemodynamics stabilized.
Noninvasive rapid urinary trypsinogen-2 dipstick test for early exclusion of post-endoscopic retrograde cholangiopancreatography pancreatitis within hours after endoscopic retrograde cholangiopancreatography: Clinical diagnosis and considerations.
DEN Open
April 2024
Department of Gastroenterology and Hepatology Tokyo Medical University Tokyo Japan.
Objective: Few reports have explored the application of urinary trypsinogen-2 measurement in the early diagnosis of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis, and none have demonstrated the benefits of noninvasive testing. This study aimed to evaluate the clinical application of the rapid urinary trypsinogen-2 dipstick test (Nipro, Japan) compared with serum amylase and lipase levels for the early diagnosis of post-ERCP pancreatitis (PEP).
Methods: A total of 100 consecutive patients (54 men and 46 women) who were admitted and underwent ERCP at Tokyo Medical University Hospital from August 2021 to December 2021 were recruited.
Background: The potential for developing frailty exists in middle-aged and older adults. While obesity and metabolic syndrome (MetS) increase the risk of frailty in older adults, this relationship remains unclear in middle-aged adults, who are prone to developing lifestyle-related diseases.
Objective: To examine the effect of overweight/obesity and MetS on frailty development in middle-aged and older Japanese adults using real-world data.
Assisted reproductive technology in Japan: A summary report for 2021 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology.
Reprod Med Biol
December 2023
Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Purpose: The Japan Society of Obstetrics and Gynecology (JSOG) registry gathers comprehensive data from registered assisted reproductive technology (ART) facilities in Japan. Herein, we report 2021 ART cycle characteristics and outcomes.
Methods: Descriptive statistics were used to summarize and analyze 2021 data.
Background: During transvenous lead extraction (TLE), a GlideLight laser sheath (Philips) cannot always be advanced over the lead, and crossover to the Evolution system (i.e., an Evolution RL sheath or Evolution Shortie RL sheath [Cook Medical]) is required.
View Article and Find Full Text PDFKey Clinical Message: The combination of superior laryngeal nerve block can reduce the respiratory depression that occurs during management under total intravenous anesthesia.
Abstract: Anesthetic management of endobronchial stent placement by rigid bronchoscopy requires the maintenance of spontaneous breathing while suppressing upper airway reflexes. The combination of superior laryngeal nerve block (SLNB) can reduce the respiratory depression that occurs during management under total intravenous anesthesia.
Objectives: Endoscopic transpapillary gallbladder drainage (ETGBD) is a highly technical procedure, but few studies have evaluated factors that predict its technical success. Therefore, in this study, we sought to identify predictors of technically successful ETGBD.
Methods: One hundred and eighty-two patients who underwent ETGBD for acute cholecystitis at our hospital were retrospectively investigated.