Desmoplastic response in biopsy specimens of early colorectal carcinoma is predictive of deep submucosal invasion.

Purpose: The aim of this study was to evaluate the role of histopathology of biopsy specimens in predicting depth of infiltration in early colorectal carcinomas before treatment.

Methods: Early colorectal carcinomas that had been resected surgically or endoscopically between 1984 and 1995 were analyzed. Histopathologic findings, including differentiation of adenocarcinoma and a desmoplastic response were investigated.

Diagnosis of lumbar disc herniation by three-dimensional MRI.

The lumbo-sacral region has anatomical lordosis and two-dimensional magnetic resonance imaging (2D-MRI) cannot therefore show spinal roots including the dorsal root ganglions in one picture. This makes it difficult to present the lateral part of spinal root lesions. We have recently described a new three-dimensional magnetic resonance imaging (3D-MRI) method which allows a stereoscopic view of the spinal cord and spinal nerve roots.

Pyoderma gangrenosum following cytosine arabinoside, aclarubicin and granulocyte colony-stimulating factor combination therapy in myelodysplastic syndrome.

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis, which may be associated with systemic conditions such as hematologic disorders. We present a patient who had been diagnosed as having myelodysplastic syndrome associated with PG at onset, in whom a febrile ulcerative skin lesion developed following cytosine arabinoside, aclarubicin and granulocyte colony-stimulating factor (G-CSF) combination chemotherapy in the course of the disease. Skin biopsy revealed dense neutrophilic infiltrate in the dermis with central epidermal ulceration, consistent with the diagnosis of PG.

[Experience in ESWL monotherapy using Lithostar--comparative study on the efficacy of standard-tube with C-tube].

Between October 1990 and April 1996, we treated 892 upper urinary tract stones with ESWL therapy using Lithostar (Siemens Medizinische Technik, Erlangen, Germany). In March 1993, the coupling head of lithotriptor was upgraded from "standard-tube" to "C-tube". The C-tube has approximately two times or more destructive energy and intensity than the standard-tube.

Prednisolone therapy for intra-abdominal desmoid tumors in a patient with familial adenomatous polyposis.

The management of intra-abdominal desmoid tumors in patients with familial adenomatous polyposis (FAP) is very difficult. Non-steroidal anti-inflammatory drugs (NSAIDs), anti-estrogenic agents, and steroids are most commonly used, because surgical removal of these tumors may result in severe morbidity, with local recurrence being common. We report a patient with FAP and intra-abdominal desmoid tumors that regressed markedly after prednisolone therapy.

[A case report of ileovesical fistula in radiation enteritis].

A 49-year-old female was admitted with chief complaint of fecaluria on March 4th 1993. A radiation therapy had been performed for uterocervical cancer 18 years ago. The small intestine and bladder was detected by DIP- and cystogram simultaneously.

[Acute pulmonary disease in systemic lupus erythematosus successfully treated with prednisolone pulse therapy].

A 46-year-old man was admitted to the hospital because of chest pain and left pleural effusion. Fever and dyspnea developed on the third hospital day. Interstitial shadows and pleural effusions in both lower lung fields appeared on chest roentgenograms.

[Primary Sjögren's syndrome accompanied by pleural effusion].

A 40-year-old woman was admitted to the hospital because of fever and right cervical pain. Facial erythema developed after admission, along with interstitial shadows and pleural effusion in both lower lung fields. Microscopical examination of transbronchial lung biopsy specimens showed infiltration by lymphocytes and thickening of alveolar walls.

Diverticular disease of the colon at a regional general hospital in Japan.

Purpose: X-ray film registry records were reviewed to better understand the changing nature of diverticular disease (DD) of the colon in Japan.

Results: Among 6,849 patients undergoing barium enema examination during a eight-year period from 1985 to 1992, this condition was found in 1,074 patients (15.7 percent), including 702 males (65.

[A case of endocrinologically active retroperitoneal ganglioneuroma].

A 27-year-old female complained of right upper abdominal pain. Computed tomography revealed a retroperitoneal tumor located between the right kidney and the vena cava. The preoperative value of noradrenaline in urine was high, 221.

[Hyperbaric oxygen therapy in the successful treatment of two cases of radiation-induced hemorrhagic cystitis].

Hemorrhagic cystitis resulting from radiation to pelvic visceral malignant lesions often might be incurable and there have been established no definitive treatment. We experienced 2 cases with radiation-induced severe hemorrhagic cystitis refractory to conventional therapy. The treatment with hyperbaric oxygen to control hematuria was performed and obtained successful results.

[Bladder carcinoma producing granulocyte colony stimulating factor (G-CSF). A case report].

A 69-year-old woman was admitted to the hospital complaining of general fatigue and lower abdominal pain. She had undergone total cystectomy because of invasive recurrent bladder carcinoma three months ago. Histopathological diagnosis was transitional cell carcinoma (TCC) grade 3 and squamous cell carcinoma (SCC), pT3a.

[A case of intrascrotal neurilemmoma].

The case was in a 65-year-old male who complained of right scrotal painless swelling. Surgical excision was performed. The tumor was placed in tunica dartos but did not connect with the testis, epididymis and spermatic cord.

[An aged case of peripheral arterial obstructive disease with progressive limb necrosis].

An aged case of peripheral arterial obstructive disease with progressive limb necrosis is reported. A 70-year old man was admitted to our hospital with the complaint of numbness and rest pain on left lower limb. Thereafter, necrosis of the digital region of the upper limbs and the toe region of the lower limbs became progressively worse 3 weeks after onset.