281 results match your criteria: "Tokushima Red Cross Hospital.[Affiliation]"

We report a 48-year-old woman with bullous pemphigoid (BP) with antibodies against the B3 subunit of laminin 332 after the development of graft-versus-host disease (GVHD). She was diagnosed with recurrent acute lymphoblastic leukemia at 40 years of age and underwent two rounds of allogeneic peripheral blood stem cell transplantations (PBST). Two and a half years after the second PBST, multiple tense blisters appeared on her face, hands, and lower legs.

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  • A study evaluated the long-term effects of a neoadjuvant chemotherapy regimen (S-1 and low-dose docetaxel) in patients with operable breast cancer, finding it to be well-tolerated and effective.
  • In an analysis of 83 patients over about 99 months, the 5-year disease-free survival (DFS) was 80.7% and overall survival (OS) was 90.9%, with the pathological complete response (pCR) group showing significantly better OS rates (100% vs. 86.2%).
  • Factors like high tumor-infiltrating lymphocytes and nuclear grade were identified as predictors of pCR, along with certain microRNAs that were notably upregulated in
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  • * Data from 4,088 lesions were analyzed, revealing that PRA was used in 19.2% of cases, with high success rates for both guidewire (93.6%) and technical procedures (91.3%).
  • * Key characteristics linked to the use of PRA included previous coronary artery bypass surgery, chronic kidney disease, and specific lesion features like blunt stumps and distal runoff under 1 mm, providing insights for choosing PCI strategies in clinical practice.
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Background: Next-generation sequencing (NGS) analysis is becoming indispensable for the treatment of advanced lung cancer. NGS analysis requires a large number of cancer cell-containing tissues; however, it is often difficult for small biopsies to obtain the required quantities. In microdissection, only the tumour parts of a tissue specimen are obtained, which thereby increases the tumour content and tumour cell count of the tissue specimen.

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  • - This study investigated the relationship between the severity of contrast extravasation (CE) seen on CT scans and the need for massive transfusions (MT) in children with blunt liver and/or spleen injuries, over a span from 2008 to 2019.
  • - The research included 1,407 pediatric patients, revealing that 14% required MT, and specific types of CE, particularly intraparenchymal and into the peritoneal cavity, significantly correlated with increased transfusion needs.
  • - The findings suggest that recognizing active CE during initial CT scans can guide healthcare providers in making informed decisions about transfusion strategies for young patients with these types of injuries.
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Introduction: The use of immune checkpoint inhibitors (ICIs) is rapidly expanding in cancer treatment. ICIs have a unique safety profile, characterised by immune-related adverse events (irAEs). The safety profile of ICIs lacks patient experience and perspectives.

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A 57-year-old woman with critical limb-threatening ischemia (CLTI) of the left lower leg underwent endovascular therapy. She had undergone a femoropopliteal (F-P) bypass for treatment of chronic total occlusion (CTO) of the superficial femoral artery (SFA) four years prior.

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  • Chronic total occlusion (CTO) PCI is complex and varies in success rates among the three major coronary arteries due to differences in lesion characteristics.
  • The study analyzed 6,408 first-attempt CTO patients from a Japanese registry to identify predictors of unsuccessful PCI and developed a difficulty score for surgical outcomes.
  • Results showed that success rates were lowest for the left circumflex artery, with key differences in predictors of failure across arteries, and the new difficulty score outperformed the J-CTO score in forecasting PCI success.
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Background: There are no studies comparing single-session vs staged multivessel intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in patients with chronic coronary syndrome (CCS) or non-ST-segment-elevation acute coronary syndrome (NSTE-ACS).

Objectives: The authors aimed to compare single-session vs staged multivessel IVUS-guided PCI in patients with CCS or NSTE-ACS.

Methods: The OPTIVUS-Complex PCI study multivessel cohort was a prospective multicenter single-arm trial enrolling 1,021 patients with CCS or NSTE-ACS undergoing multivessel PCI including left anterior descending coronary artery using IVUS aiming to meet the prespecified OPTIVUS criteria for optimal stent expansion.

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In recent years, radiochromic films have begun to be used for dosimetry in mammography; however, the most sensitive GAFCHROMIC XR-QA2 (XR-QA2) film is no longer available owing to its discontinuation. In this study, we evaluated the sensitivity characteristics of GAFCHROMIC LD-V1 (LD-V1) as an alternative to XR-QA2 in the field of mammography, at a low dose and low energy. Our results show that the average ratio of the concentration change of LD-V1 divided by the concentration change of XR-QA2 at each absorbed dose was 53.

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Background: We recently reported on a late preterm infant born at 36 weeks' gestation with serious arrhythmia due to hyperkalemia associated with long-term maternal ritodrine administration. It is unknown whether ritodrine alone increases the risk of neonatal hyperkalemia in infants born at 34-36 weeks' gestation.

Methods: This single-center, retrospective, cohort study enrolled late preterm infants (34-36 gestational weeks) born between 2004 and 2018.

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Pituitary gamma knife surgery (GKS) is a treatment option for poststroke thalamic pain syndrome. Complications such as hypopituitarism, transient enuresis, and transient hyponatremia have been reported. However, cerebrospinal fluid (CSF) leakage has not yet been reported as a complication of pituitary GKS for poststroke thalamic pain syndrome.

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  • This study investigates the relationship between contrast media volume (CMV) and contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD) undergoing percutaneous coronary intervention (PCI) for chronic total occlusion (CTO).
  • Results show that a minimum CMV of 50 mL or less significantly reduces the incidence of CIN compared to a higher CMV (1.0% vs. 4.1%, p = 0.03).
  • Additionally, patients in the minimum CMV group experienced higher success rates (96.8% vs. 90.3%) and fewer complications (3.1% vs. 7.1%) as well as a greater use of the
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The outbreak of coronavirus disease (COVID-19) resulted in implementation of social distancing and other public health measures to control the spread of infection and improve prevention, resulting in a decrease in respiratory syncytial virus (RSV) and pediatric respiratory tract infection rates. However, there was a rapid and large re-emergence of RSV infection in Japan. Notably, we were faced with a difficult situation wherein there was a shortage of hospital beds.

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(1) Background: The probability of technical success in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) represents essential information for specifying the priority of PCI for treatment selection in patients with CTO. However, the predictabilities of existing scores based on conventional regression analysis remain modest, leaving room for improvements in model discrimination. Recently, machine learning (ML) techniques have emerged as highly effective methods for prediction and decision-making in various disciplines.

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Introduction: Associations of luteinizing hormone (LH) with androgens during the menopausal transition and associations between follicle-stimulating hormone (FSH) levels and various diseases related to reproductive hormones in postmenopause have received much attention. LH and FSH are also known to be associated with activities of enzymes related to reproductive hormones. We examined the associations of LH and FSH with androgens and estrogens in each stage of the menopausal transition according to a classification from menopausal transition to postmenopause.

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The effects of lead equivalent and lens area of radiation-protective eyewear on lens exposure control were examined. The simulated patient underwent 10-min X-ray fluoroscopy, and the lens dose of the simulated surgeon wearing radiation protection glasses was measured using lens dosemeters attached to the corner of the eye and eyeball. In total, 10 types of radiation protection glasses were selected for measurement.

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Mammography is one of the most effective diagnostic methods for the early detection of breast cancer; however, it poses the risk of radiation exposure. To date, mammography dosimetry has been performed according to the mean glandular dose; however, the actual exposure in the breast has not been assessed. Here, we have measured dose distributions and depth doses using both radiochromic films and mammographic phantoms, and a three-dimensional intra-mammary dose assessment was conducted.

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Background: There is a scarcity of data evaluating contemporary real-world dual antiplatelet therapy (DAPT) strategies after percutaneous coronary intervention (PCI).

Methods and results: In the OPTIVUS-Complex PCI study multivessel cohort enrolling 982 patients undergoing multivessel PCI, including left anterior descending coronary artery using intravascular ultrasound (IVUS), we conducted 90-day landmark analyses to compare shorter and longer DAPT. DAPT discontinuation was defined as withdrawal of P2Yinhibitors or aspirin for at least 2 months.

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Background: Several stent expansion criteria derived from the intravascular ultrasound (IVUS) evaluation have been proposed to predict future clinical outcomes, but optimal stent expansion criteria as a guide during percutaneous coronary intervention (PCI) are still controversial. There are no studies evaluating the utility of stent expansion criteria along with the clinical and procedural factors in predicting target lesion revascularization (TLR) after contemporary IVUS-guided PCI.

Methods: OPTIVUS-Complex PCI study (Optimal Intravascular Ultrasound Guided Complex Percutaneous Coronary Intervention) multivessel cohort was a prospective multicenter study enrolling 961 patients undergoing multivessel PCI including left anterior descending coronary artery using IVUS with an intention to meet the prespecified criteria for optimal stent expansion.

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  • The study explored the impact of intravascular ultrasound (IVUS) on patient outcomes in those with multivessel disease undergoing percutaneous coronary intervention (PCI), showing it was infrequently used in past trials.
  • The OPTIVUS-Complex PCI study enrolled 1,021 patients to evaluate the effectiveness of IVUS-guided PCI, aiming to achieve optimal stent expansion based on specific criteria.
  • Results indicated a 1-year major adverse cardiac and cerebrovascular events (MACCE) rate of 10.3%, which was significantly lower than the predefined PCI goal of 27.5%, suggesting that contemporary PCI practices may lead to better outcomes in this patient group.
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Left anterior descending artery (LAD) occlusion normally develops into precordial ST-segment elevation; however, we describe a case of a 50-year-old man with inferior and precordial ST-segment elevation myocardial infarction that resulted from proximal occlusion of the wrap-around LAD perfusing the anterior and inferior wall. We performed early and prompt reperfusion and were able to save the patient without any complications. A wrap-around LAD perfuses a large myocardial area; therefore, this type of coronary occlusion causes severe myocardial damage and has a poor prognosis.

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