Ternifolipyrons A-J: new cytotoxic α-pyrones from (D. Don) Kudô.

(D.Don) Kudô is an important Asian herb used in traditional medicine against several diseases. Nineteen compounds were isolated from the dichloromethane-methanol (1 : 1) extract of roots, including ten new α-pyrone derivatives, named ternifolipyrons A-J.

Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral .

A solvent extract of the soft coral afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).