2,931 results match your criteria: "Tokat Gaziosmanpaşa University[Affiliation]"

Toxic environmental pollutants are considered to be posed a major threat to human and aquatic systems. The fast advancement of the petrochemical and chemical industries has woken up rising worries concerning the pollution of water by contaminants including phenolic Bisphenol A (BPA), an endocrine-disrupting chemical (EDC). The intermediate BPA used in synthesis of certain plastics, polycarbonate polymers, polysulfone, and epoxy resins of various polyesters.

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Does Illness Perception Predict Hopelessness and Death Anxiety in Palliative Care Patients?

Omega (Westport)

December 2024

Department of Nursing, Faculty of Medicine Research and Application Hospital, Sivas Cumhuriyet University, Sivas, Turkey.

Illness perception is crucial in how patients navigate health challenges. Investigating if it predicts hopelessness and death anxiety is vital, especially in palliative care where these burdens are common. This descriptive, cross-sectional study was conducted with 129 patients receiving treatment in the palliative care clinics of a university hospital.

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Acute effect of instrument-assisted soft tissue mobilization on hamstring flexibility via fascial chain.

BMC Musculoskelet Disord

December 2024

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Tokat Gaziosmanpaşa University, Taşlıçiftlik Campus, Tokat, 60250, Türkiye.

Background: Soft tissue techniques are frequently used to treat musculoskeletal disorders. Releasing the muscles through intervention from remote areas is especially important in cases where the muscles are sensitive, inaccessible or cannot be positioned appropriately. This study aimed to examine the effect of instrument-assisted soft tissue mobilization (IASTM) on hamstring flexibility via the fascial chain.

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Extraction and characterization of microcrystalline cellulose from carrot pomace using green pretreatment technologies.

Food Chem

December 2024

Tokat Gaziosmanpasa University, Faculty of Engineering and Architecture, Food Engineering Dept., 60150 Tokat, Turkey. Electronic address:

In this study, microcrystalline cellulose (MCC) from carrot pomace, which is a byproduct of the carrot process, was produced. The Response Surface Methodology optimized the effectiveness of autoclaving & ultrasonic pretreatments (AUP) in MCC extraction with a D-optimal design. The yield of AUP was 36.

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Headache Disability Questionnaire: cross-cultural adaptation and validation of the Turkish version.

BMC Neurol

December 2024

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Tokat Gaziosmanpasa University, Tokat, 60250, Turkey.

Background: The Headache Disability Questionnaire (HDQ) evaluates pain intensity, daily activities, work/school disruptions, and the impact on recreational activities. It was aimed to translate the HDQ into Turkish and evaluate its reliability and validity.

Methods: This study included 130 participants, consisting of 105 females and 25 males.

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Herbal products are valuable biological resources of bioactive compounds expressed as secondary metabolites. This study aimed to explore the potential biological properties and phenolic content of Cyanus celikhanensis, which has no data on pharmacological properties. A quantitative phytochemical analysis of C.

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Microwave energy is based on creating heat in the structure by creating vibrations in the moisture in the product used. In drying processes, drying kinetics, energy consumption, quality, and so on features are evaluated based on the temperature equivalent of the heat created by the heat source in the product. For this reason, the temperature value formed in the product in microwave drying processes is important.

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In this study, a simple, accurate, and precise analytical strategy was developed for the determination of total nitrogen (total dissolved nitrogen + particulate nitrogen) in surface waters using smartphone technology. The spectrophotometric method based on digestion with persulfate, commonly used in water analyses, was integrated with a digital image-based colorimetric detection system (DIC). To evaluate the accuracy of the total nitrogen-digital image-based colorimetric detection system (TN-DIC), results obtained from the Hach method and UV-VIS spectrophotometer were compared with the RGB values obtained from the smartphone imaging system.

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Purpose: Our study aimed to evaluate the incidence and anatomical locations of cerebral venous malformations (CVMs), their alterations over time, and magnetic resonance imaging (MRI) findings of their relationships with each other in patients who underwent magnetic susceptibility-weighted imaging (SWI) and contrast-enhanced MRI.

Methods: The drainage pattern of developmental venous anomalies (DVAs), the number of collecting veins, DVA thrombosis, signal-intensity abnormalities, and hemosiderin deposits (nodular, diffuse, or both) related to the DVA, were examined. The alterations over time in cavernomas (type and size) were assessed.

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Tissue culture and cloning are valuable techniques in plant biology research as they enable the production of genetically identical plants, which may be utilized for many purposes such as crop enhancement, plant breeding, and genetic manipulation. Helichrysum arenarium (L.) Moench (HA), also known as immortelle or strawflower (Asteraceae), is a species of flowering plant in the sunflower family.

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This study aimed to determine the physical (height, weight, volume, color, etc.), chemical (protein, fat, ash, moisture, etc.), functional (total phenolic, flavonoid, and antioxidant capacity), nutritional (total, soluble, insoluble dietary fiber, and important starch fractions), and texture properties and volatile organic compounds of traditional Tokat bread.

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Article Synopsis
  • Teriflunomide is an oral medication for treating relapsing-remitting multiple sclerosis by inhibiting T and B lymphocyte proliferation.
  • Common side effects include headache, elevated liver enzymes, hair thinning, and joint pain.
  • Two reported cases show that patients developed restless legs syndrome after starting teriflunomide, highlighting the need to monitor for this potential side effect in MS patients.
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Article Synopsis
  • - Sepsis is a serious condition characterized by inflammation and cell death, often leading to multiple organ failure, requiring quick medical attention; lipopolysaccharide (LPS) triggers inflammatory responses through specific receptors like TLR-2.
  • - The study explores the role of melatonin (MEL) in reducing lung injury caused by LPS-induced septic shock in rats, highlighting its potential to lower the expressions of inflammatory markers NEK7, TLR2, and NLRP3.
  • - Results showed that melatonin treatment reduced lung tissue damage, cell infiltration, and wall thickening, indicating that it may provide therapeutic benefits in managing sepsis-related acute lung injury.
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Background: Mouth rinsing (MR) with a carbohydrate solution is one of the most popular methods athletes use to improve their game-based performance due to its acute ergogenic effect.

Objectives: This study aimed to evaluate the effects of the carbohydrate MR intervention on psychophysiological responses and kinematic profiles during intermittent () and continuous () 4-a-side small-sided soccer games (SSGs).

Methods: Thirty-two adolescent soccer players (age: 16.

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Severe and post-COVID-19 are associated with high expression of vimentin and reduced expression of N-cadherin.

Sci Rep

November 2024

Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Tokat Gaziosmanpasa University, 60200, Tokat, Turkey.

Article Synopsis
  • SARS-CoV-2 enters human cells through its spike protein, mainly binding to ACE2 receptors, which leads to viral replication and an overstimulated immune response known as a cytokine storm.
  • This study investigated the expression of vimentin, a protein linked to endothelial dysfunction and fibrosis, in severe COVID-19 patients, those recovering, and healthy controls.
  • Results showed that severe COVID-19 patients had higher vimentin levels and gene expression compared to healthy individuals, while N-cadherin levels were lower, suggesting these proteins could serve as potential diagnostic markers for the disease.
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We aimed to investigate whether pulsed magnetic fields (PMFs) (1 mT) may have preventive effects on myocardial damage and apoptosis in rats with sepsis. Twenty-eight adult Wistar albino rats were evenly distributed among four experimental groups, each consisting of seven rats: SH, LF-PMF, HF-PMF, and CLP. Sepsis induction was carried out via the cecal ligation and puncture (CLP) method, while rats in the LF-PMF and HF-PMF groups were exposed to 7.

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The present study aimed to provide experimental evidence that CDELNs (coffee-derived exosome-like nanoparticles) may be a candidate for the treatment or prevention of amyloid-β (Aβ)-induced Alzheimer's disease (AD). An in vitro Alzheimer's model was created with Aβ-induced toxicity in mouse hippocampal neuronal cells (HT-22). Aβ(1-42)-exposed cells were treated with different concentrations of CDELNs (1-50 μg/ml) and the viability of cells was analyzed.

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Article Synopsis
  • The study investigates the impact of COVID-19 on olfactory pathways by analyzing 63 autopsy cases, comparing 37 COVID-19 victims with 26 non-COVID controls.
  • Researchers measured various anatomical structures in the olfactory system and found significant reductions in the volume, weight, and dimensions of the olfactory bulbs and tracts in the COVID-19 group.
  • The findings suggest that COVID-19 causes notable damage to the olfactory centers, indicating the importance of understanding these changes for clinical and future research efforts related to the disease.
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The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding.

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