51 results match your criteria: "Tokai Gakuin University[Affiliation]"
MethodsX
June 2025
College of Life and Health Sciences, Chubu University, Kasugai, Aichi Japan.
This study aimed to assess fatigue using a noninvasive, quantitative, and simple method using salivary chromogranin A (CgA). In total, 171 adults participated in this study. We used the Cornell Medical Index (CMI) as a questionnaire that included a fatigability section.
View Article and Find Full Text PDFMem Cognit
December 2024
Faculty of Human Cultures and Sciences, Fukuyama University, Hiroshima, Japan.
This study examined informative and uninformative anchoring effects on judgments of learning (JOLs), focusing on two hypotheses: the optimistic/pessimistic and differential-scaling hypotheses. The optimistic/pessimistic hypothesis states that anchoring information changes subjective confidence in memory, whereas the differential-scaling hypothesis states that anchoring information elicits a scaling bias in the conversion process of subjective internal confidence into scale JOLs (i.e.
View Article and Find Full Text PDFSci Rep
November 2024
Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Body Image
December 2024
Faculty of Letters, Chuo University, 742-1 Higashinakano Hachioji-shi, Tokyo 192-0393, Japan.
Body Image
December 2024
Faculty of Letters, Chuo University, 742-1 Higashinakano Hachioji-shi, Tokyo 192-0393, Japan.
This study evaluated the reliability and validity of the Japanese version of the Body Talk Scale (BTS), designed to measure negative fat talk, negative muscle talk, and positive body talk. The study also explored the longitudinal associations between each body talk category and body dissatisfaction. We conducted two separate studies among university students in Japan.
View Article and Find Full Text PDFCommun Biol
April 2023
Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
Skeletal muscle is sensitive to gravitational alterations. We recently developed a multiple artificial-gravity research system (MARS), which can generate gravity ranging from microgravity to Earth gravity (1 g) in space. Using the MARS, we studied the effects of three different gravitational levels (microgravity, lunar gravity [1/6 g], and 1 g) on the skeletal muscle mass and myofiber constitution in mice.
View Article and Find Full Text PDFFront Cell Dev Biol
March 2023
Faculty of Health and Welfare, Tokai Gakuin University, Kakamigahara, Japan.
The dynamic assembly of actin is controlled by the hydrolysis of ATP, bound to the center of the molecule. Upon polymerization, actin undergoes a conformational change from the monomeric G-form to the fibrous F-form, which is associated with the flipping of the side chain of His161 toward ATP. His161 flipping from the gauche-minus to gauche-plus conformation leads to a rearrangement of the active site water molecules, including ATP attacking water (W1), into an orientation capable of hydrolysis.
View Article and Find Full Text PDFFront Psychol
November 2022
Graduate School of Education, Kyoto University, Kyoto, Japan.
Fantasy is the experience of identifying with characters in movies, novels, plays, and other fictional situations. In social contexts, individuals take on the perspective of others by sensing their emotions through empathy. During this process, perspective-taking and emotional sharing affect one's metacognition, which deals with the distinction between and the understanding of one's emotions (clarity) and their regulation (repair); previous studies have primarily focused on these processes.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2022
Structural Biology Research Center, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
The major cytoskeleton protein actin undergoes cyclic transitions between the monomeric G-form and the filamentous F-form, which drive organelle transport and cell motility. This mechanical work is driven by the ATPase activity at the catalytic site in the F-form. For deeper understanding of the actin cellular functions, the reaction mechanism must be elucidated.
View Article and Find Full Text PDFJ Ration Emot Cogn Behav Ther
July 2022
Faculty of Letters, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe, Hyougo 658-8501 Japan.
Background: In the past, different stress generation studies have used self-report measures comprising different items to assess each category of negative events. Moreover, the validity of these scales has not been adequately investigated. Therefore, we developed a self-report measure dedicated to assessing experiences of negative interpersonal dependent events, negative non-interpersonal dependent events, and negative independent events in university students, which was named the Negative Independent/Dependent Events Scale.
View Article and Find Full Text PDFCurr Psychol
February 2022
Graduate Schools of Health Sciences, Hirosaki University, 66-1, Hon-cho, Hirosaki-shi, Aomori, 036-8564 Japan.
Unlabelled: The present study examined the causes and consequences of stress generation in university students in Japan. A two-wave longitudinal study with an 8- or 9-week interval was conducted in the fall of 2020. Undergraduate and graduate students at four universities in Japan ( = 201) completed self-report measures assessing experiences of negative interpersonal dependent events, negative non-interpersonal events, and negative independent events at two times.
View Article and Find Full Text PDFPsychol Res
October 2022
Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 1-1, Minamijosanjima-cho, Tokushima, 770-8502, Japan.
Sci Rep
August 2021
Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration Agency, Tsukuba, Japan.
Previous research on the relationship between rumination and behavioral impulsivity has been limited because impulsivity was assessed by using individual tasks. This study examined the concurrent associations of a latent variable named impulsive action with rumination and depression to alleviate the task-impurity problem and the low reliability of laboratory tasks assessing impulsivity. This study also examined whether stressors mediated the association between impulsive action and rumination.
View Article and Find Full Text PDFPsychol Res
April 2022
Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 1-1, Minamijosanjima-cho, Tokushima, 770-8502, Japan.
Previous findings on relationships between inhibition that is a core executive function, and trait rumination have been inconsistent. This inconsistency could be overcome by investigating the association between rumination and the two subcomponents of inhibition: response inhibition and attentional inhibition. This study examined whether and how response inhibition and attentional inhibition were related to rumination as well as worry.
View Article and Find Full Text PDFSci Rep
January 2021
Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration Agency, Tsukuba, Japan.
Many experiments have analyzed the effect of the space environment on various organisms. However, except for the group-rearing of mice in space, there has been little information on the behavior of organisms in response to gravity changes. In this study, we developed a simple Active Inactive Separation (AIS) method to extract activity and inactivity in videos obtained from the habitat cage unit of a space experiment.
View Article and Find Full Text PDFScand J Psychol
April 2021
Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 1-1, Minamijosanjima-cho, Tokushima, 770-8502, Japan.
Young, Sutherland, and McCoy indicated that a Go/No-Go Task (GNG) becomes more difficult as the inter-stimulus intervals (ISIs) becomes shorter. However, is the number of commission errors under extremely short ISIs a useful metric for assessing response inhibition? This study challenges the assumption that a shorter ISI in the GNG enables better assessment of response inhibition. University students (N = 213) completed the GNG, the Conners Continuous Performance Test 3rd Edition (CCPT), and the Modified Stroop Task.
View Article and Find Full Text PDFNagoya J Med Sci
May 2020
College of Life and Health Sciences, Chubu University, Kasugai, Japan.
Resveratrol (RSV) has recently attracted keen interest because of its pleiotropic effects. It exerts a wide range of health-promoting effects. In addition to health-promoting effects, RSV possesses anti-carcinogenic activity.
View Article and Find Full Text PDFBiomolecules
May 2020
Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Depolymerization and polymerization of the actin filament are indispensable in eukaryotes. The DNase I binding loop (D-loop), which forms part of the interface between the subunits in the actin filament, is an intrinsically disordered loop with a large degree of conformational freedom. Introduction of the double mutation G42A/G46A to the D-loop of the beta cytoskeletal mammalian actin restricted D-loop conformational freedom, whereas changes to the critical concentration were not large, and no major structural changes were observed.
View Article and Find Full Text PDFBiochem Biophys Res Commun
May 2020
College of Life and Health Sciences, Chubu University, Kasugai, 487-8501, Japan. Electronic address:
T315I mutation found in chronic myelogenous leukemia (CML) and Ph + ALL patients is the most serious one among resistance against BCR/ABL kinase inhibitors including imatinib and is only responsive to ponatinib (PNT). However, the novel strategy is required to reduce life-threatening adverse effects of PNT including ischemic cardiovascular disease. We examined the mechanism of PNT-induced cytotoxicity against a T315I(+) Ph + ALL cell line, TccY/Sr.
View Article and Find Full Text PDFJ Muscle Res Cell Motil
March 2020
Structural Biology Research Center, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Gelsolin superfamily proteins, consisting of multiple domains (usually six), sever actin filaments and cap the barbed ends in a Ca-dependent manner. Two types of evolutionally conserved Ca-binding sites have been identified in this family; type-1 (between gelsolin and actin) and type-2 (within the gelsolin domain). Fragmin, a member in the slime mold Physarum polycephalum, consists of three domains (F1-F3) that are highly similar to the N-terminal half of mammalian gelsolin (G1-G3).
View Article and Find Full Text PDFJ Mol Biol
August 2019
Structural Biology Research Center, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan; Toyota Physical and Chemical Research Institute, 41-1 Yokomichi, Nagakute, Aichi 480-1192, Japan. Electronic address:
Information on the structural polymorphism of a protein is essential to understand the mechanisms of how it functions at an atomic level. Numerous studies on actin have accumulated substantial amounts of information about its polymorphism, and there are over 200 published atomic structures of different forms of actin using crystallography, fiber diffraction, and electron microscopy. To characterize all the reported structures, we proposed simple parameters based on the discrete rigid bodies within the actin molecule and identified four conformation groups by cluster analysis: the F-form in naked F-actin, the C-form in cofilactin, the O-form in profilin-actin, and the G-form in the majority of actin-containing crystal structures.
View Article and Find Full Text PDFEnviron Health Prev Med
January 2019
Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Background: We aimed to examine the association of exposure to environmental tobacco smoke with dental caries among preschool children. Exposure to environmental tobacco smoke was assessed in terms of urinary cotinine concentrations and pack-years of exposure to smoking by parents and other family members at home.
Methods: This cross-sectional study included 405 preschool children aged 3-6 years from two preschools in Japan in 2006.
Biophys Rev
December 2018
Structural Biology Research Center, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Polymerization induces hydrolysis of ATP bound to actin, followed by γ-phosphate release, which helps advance the disassembly of actin filaments into ADP-G-actin. Mechanical understanding of this correlation between actin assembly and ATP hydrolysis has been an object of intensive studies in biochemistry and structural biology for many decades. Although actin polymerization and depolymerization occur only at either the barbed or pointed ends and the kinetic and equilibrium properties are substantially different from each other, characterizing their properties is difficult to do by bulk assays, as these assays report the average of all actin filaments in solution and are therefore not able to discern the properties of individual actin filaments.
View Article and Find Full Text PDFBiochem Biophys Rep
September 2018
College of Life and Health Sciences, Chubu University, Matsumoto-cho 1200, Kasugai 487-8501, Japan.
Imatinib (IMT), a specific tyrosine kinase inhibitor (TKI), has drastically changed the treatment strategy for Ph+ ALL (Philadelphia chromosome-positive acute lymphoblastic leukemia). However, TKI resistance remains a serious problem for patient prognosis. Here, a Ph+ ALL cell line NphA2 and the IMT-resistant subline NphA2/STIR were analyzed to identify a potential novel treatment strategy.
View Article and Find Full Text PDF