1,651 results match your criteria: "Tohoku University Graduate School of Dentistry.[Affiliation]"

This retrospective study aimed to kinematically classify mandibular movements collected during Temporomandibular Disorders (TMD) treatment, employing Fourier transformation (FT), Principal Component Analysis (PCA), and K-means clustering (k-means), and to investigate their correlation with symptoms of pain-related TMD. The study included five TMD participants diagnosed with myalgia (age: 39-86 years, with an SD of 18.96) and three healthy participants (age: 32-42 years, with an SD of 5.

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Effects of phototherapy in patients with idiopathic facial palsy: Scoping review.

Jpn Dent Sci Rev

December 2024

Department of Oral Medicine, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.

Phototherapy has emerged as a promising treatment for Bell's palsy, offering potential improvements in facial nerve function and overall well-being. In this study, we selected seven relevant studies involving 306 patients with subacute or acute Bell's palsy from PubMed, EMBASE, Web of Science, and Scopus before June 5, 2024. Low-level laser therapy (LLLT) efficacy for facial nerve paralysis was assessed in seven studies.

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Purpose: The COVID-19 pandemic has affected lives and dental treatment. Aerosols and droplets generated during dental treatment present a risk of infection for dental care workers. However, detailed elucidation of the conditions under which those are generated has yet to be presented, and no clear countermeasures for protection have been established.

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Article Synopsis
  • This study examines the effectiveness of different sizes of cotton swabs (large vs. fine) for nasal disinfection before nasotracheal intubation (NTI) to reduce bleeding while still sterilizing effectively.
  • Researchers conducted a randomized controlled trial with 62 patients in each cotton swab group, collecting bacterial samples before and after disinfection and after surgery.
  • Results showed no significant difference in bacterial reduction between the large and fine swabs, indicating that both swab sizes were comparably effective for nasal disinfection prior to NTI.
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This study examines the association between posterior occlusal contact and the risk of dementia development in the Japanese population, utilizing Eichner classification to evaluate occlusal status. Data from Japanese health insurance claims were analyzed for the period from April 2016 to March 2022. Participants had undergone specific health checkups, had no prior history of dementia, and were classified according to their dental occlusal contact.

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Damage to the peripheral nerves of trigeminal ganglion (TG) neurons leads to intractable orofacial neuropathic pain through the induction of neuroinflammation. However, the details of this process are not yet fully understood. Here, we found that fibroblast-derived interleukin (IL)-33 was required for the development of mechanical allodynia in whisker pad skin following infraorbital nerve injury (IONI).

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Evaluating Methodological validity in the Analysis of Tai Chi and cognitive behavioral therapy for inflammation Reduction in Insomnia: A Letter to the Editor.

Brain Behav Immun

January 2025

Scientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan; Department of Internal Medicine, Kyoto Min-iren Asukai Hospital, Kyoto, Japan; Section of Clinical Epidemiology, Department of Community Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Healthcare Epidemiology, Kyoto University Graduate School of Medicine / Public Health, Kyoto, Japan; Department of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Sendai, Japan.

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Orthodontic management of severe inversely impacted maxillary central incisors: a case series.

Front Oral Health

October 2024

Division of Pediatric Dentistry, Department of Oral Health and Development Sciences, Tohoku University Graduate School of Dentistry, Sendai, Japan.

Background: Abnormal positioning and dislocation of the central incisor can disturb tooth eruption. Generally, inversely impacted maxillary central incisors do not erupt naturally. Performing traction and applied extrusion of an inversely impacted maxillary central incisor with a high inclination angle of the crown is challenging.

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Although the benefits of anti-hypertensive treatment are well known, the proportion of hypertensive patients with controlled blood pressure (BP) remains suboptimal. The present study aimed to compare BP control conditions in a hypertension-specialized clinic and non-hypertension-specialized clinics. This cross-sectional study used data from 379 treated patients who measured home BP in the Ohasama study between 2016 and 2019 (men: 43.

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Article Synopsis
  • Cognitive function is vital for both young and older adults, and it's important to address cognitive and oral function declines together, as they can influence each other.
  • The study aimed to create a training program that merges oral exercises with cognitive tasks to enhance brain activity, focusing on areas like the left DLPFC and right mPFC.
  • Results indicated that higher levels of difficulty in training led to increased brain activity, particularly during certain combined training methods involving calculations and inhibitions, highlighting the potential benefits of this integrated training approach.
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Objective: Healthy dietary patterns have been linked to lower levels of chronic inflammation. The present study aimed to investigate the associations between food group intakes and high-sensitivity C-reactive protein (hsCRP) among community-dwelling adults.

Design: Cross-sectional.

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Effects of inorganic phosphate on stem cells isolated from human exfoliated deciduous teeth.

Sci Rep

October 2024

Center of Excellence for Dental Stem Cell Biology, Faculty of Dentistry, Chulalongkorn University, 34 Henri-Dunant Road, Wang-Mai, Pathumwan, Bangkok, 10330, Thailand.

Article Synopsis
  • Calcium phosphate-based materials (CaP) show potential as dental pulp capping materials for baby teeth, with a focus on how inorganic phosphate (P) affects stem cells from exfoliated deciduous teeth (SHED).
  • Treatment with P led to an increase in late apoptosis without altering the overall cell cycle, while enhancing gene expression related to bone and tooth formation.
  • P promoted mineralization and calcium deposition but reduced fat cell formation by inhibiting specific pathways, suggesting a beneficial role for P in dental stem cell applications.
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  • Cleft lip and/or palate (CL/P) is a common birth condition that can lead to higher risks of children facing mistreatment and mothers experiencing depression.
  • A study looked at 238 mothers of babies with CL/P to see how it affected their thoughts about self-harm during the first six months after giving birth.
  • Results showed that mothers of babies with CL/P had a higher chance of thinking about self-harm compared to mothers of babies without this condition, especially if the baby had a cleft lip.
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  • The objective of the study was to assess the effects of early intensive rehabilitation after hip fracture surgery on daily living activities in patients aged 50 and older, including those with dementia.
  • The study analyzed medical claims data from 925 hospitals in Japan, comparing three different rehabilitation intensity regimens and measuring recovery through Barthel Index scores at 14 and 30 days post-surgery.
  • Results indicated that higher intensity rehabilitation improved daily living scores, especially at 30 days post-surgery, with significant benefits noted for both dementia and non-dementia patients, highlighting the importance of early rehabilitation.
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Article Synopsis
  • A 32-year-old woman had an emergency cesarean section at 35 weeks of pregnancy with spinal anesthesia, which generally has few complications.
  • Shortly after the procedure, she experienced headache and nausea, leading to confusion, and a CT scan showed she had an intracranial epidural hematoma.
  • The case underscores that even low-risk obstetric patients can develop rare but serious complications, such as an intracranial epidural hematoma after spinal anesthesia.
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Present state and perceived future use of teledentistry in long-term care facilities in Japan: A cross-sectional study.

Digit Health

September 2024

Department of Dysphagia Rehabilitation, Division of Gerontology and Gerodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Objectives: Teledentistry could be effective in managing oral health through the provision of oral hygiene instruction and diagnostic services. This study aimed to assess the perception and usefulness of teledentistry in Japanese long-term care facilities.

Methods: We conducted a questionnaire survey to compare related factors of the usefulness of teledentistry and identify issues in its implementation.

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Background/purpose: Cementum shares many properties with bone; however, in contrast to bone, it is not innervated or vascularized and has a limited capacity for remodeling. Osteocytes located in the lacunae-canalicular system of bone tissue play a central role in bone remodeling by communicating with osteoblasts and osteoclasts. Although cementocytes are present in cellular cementum and are morphologically similar to osteocytes, it remains unclear whether they are involved in the dynamic functional regulation of metabolism in cementum.

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Childhood Socioeconomic Status Affects Dental Pain in Later Life.

JDR Clin Trans Res

September 2024

Department of Oral Health Promotion, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Article Synopsis
  • - Lower socioeconomic status (SES) in childhood is linked to higher dental pain in older adults, irrespective of their current SES, highlighting a potential long-lasting impact of early life conditions on oral health.
  • - A study analyzed data from over 21,000 participants aged 65 and older, revealing that those with low childhood SES were more likely to suffer from dental pain in later life, with a significant portion of this association explained by current SES and the number of remaining teeth.
  • - The findings underscore the need for policies and interventions targeting childhood SES to promote better oral health outcomes as individuals age, emphasizing that early life conditions can shape dental health in later years.
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Introduction: A public oral health screening, periodontal disease screening, has been implemented in Japan, but it remains unclear whether screening encourages subsequent regular dental visits. This study aimed to examine whether people who underwent periodontal disease screening were more likely to regularly visit dentists after undergoing the screening than before using a difference-in-differences (DID) approach.

Methods: This study used health care claims data of municipality residents who underwent periodontal disease screening in 2017 or 2018.

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Secondhand tobacco exposure assessed using urinary cotinine among 10-year-old children in Japan: An 11-year repeated cross-sectional study.

Nicotine Tob Res

September 2024

Division of Epidemiology, School of Public Health, Graduate School of Medicine, Tohoku University, Miyagi, Japan.

Introduction: The emergence of heated tobacco products (HTPs) has made it important to monitor HTP-generated aerosols in addition to combustible cigarette (CC) smoke as a source of secondhand tobacco (SHT) exposure. We investigated the trend of SHT exposure in school-aged children and assessed whether SHT exposure depended on household tobacco use status.

Methods: This repeated cross-sectional study from 2011 to 2021 (15,927 participants) was based on data from an annual survey of fourth-grade students (aged 10 years) in Kumagaya City, Japan.

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Objectives: Previous studies have reported that tooth loss is associated with an increased risk of dementia; however, few have explored the association between number of teeth and dementia-free and total life expectancies. We investigated whether having more teeth is associated with longer dementia-free and total life expectancies.

Design: A 10-year follow-up prospective cohort study from 2010 to 2020.

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The role of real-world data, collected from clinical practice rather than clinical trials, has become increasingly important for investigating real-life situations, such as treatment effects. In Japan, evidence on hypertension, cardiovascular diseases, and kidney diseases using real-world data is increasing. These studies are mainly based on "the insurer-based real-world data" collected as electronic records, including data from health check-ups and medical claims such as JMDC database, DeSC database, the Japan Health Insurance Association (JHIA) database, or National Databases of Health Insurance Claims and Specific Health Checkups (NDB).

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Induced pluripotent stem cell-derived neural stem cells promote bone formation in mice with calvarial defects.

Acta Biomater

October 2024

Division of Craniofacial Function Engineering (Division of Biomaterials Science and Engineering), Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan. Electronic address:

Nerve-derived factors have attracted attention in bone regeneration therapy due to their ability to promote bone regeneration and nerve innervation. Mesenchymal stem cells transported to target sites promote osteogenesis. However, there are few reports on the effects of neural stem cells on bone regeneration.

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Changes in three-dimensional nasal morphology according to the direction of maxillary movement during Le Fort I osteotomy.

J Plast Reconstr Aesthet Surg

November 2024

Division of Oral and Maxillofacial Reconstructive Surgery, Department of Disease Management Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan. Electronic address:

Background: Le Fort I (LFI) osteotomy is commonly performed by orthognathic surgeons; however, postoperative changes in nasolabial morphology are of concern. Several factors influence such changes, but it is difficult to accurately predict the postoperative results. This study evaluated the three-dimensional (3D) morphological changes in the nasal region according to the different directions of maxillary movement during LFI osteotomy.

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Surgery-early approach combined with condylectomy for correction of severe facial asymmetry with mandibular condylar hyperplasia: a case report.

J Korean Assoc Oral Maxillofac Surg

August 2024

Division of Oral and Maxillofacial Reconstructive Surgery, Department of Disease Management Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.

In patients with unilateral mandibular condyle hyperplasia, whether to perform condylectomy and orthognathic surgical procedures at the same time or orthognathic surgery in two stages for remains controversial. Reported here is a case of facial asymmetry with mandibular condyle hyperplasia, for which condylectomy and orthognathic surgery procedures were performed at the same time. A 28-year-old woman was presented to our department with chief complaints of left deviation of the mandible and right temporomandibular joint (TMJ) noise.

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