2,078 results match your criteria: "Tinea Pedis"

Trichophyton mentagrophytes delays wound healing in ob/ob mice.

Int Wound J

December 2024

Biofunctional Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

A wide variety of microbial species, including Trichophyton spp., have been detected in diabetic foot ulcers (DFUs). In particular, Trichophyton spp.

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Dermatophytes represent the largest and most common group of fungal infections, impacting 25% of the global population. Among them, Trichophyton rubrum has emerged as the predominant species, responsible for a range of conditions such as tinea corporis, tinea pedis, onychomycosis, tinea cruris, and tinea manuum. Although dermatophyte incidence varies geographically, there is a noticeable rise in cases caused by T.

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Article Synopsis
  • * A total of 32,786 patients were recorded, with a notable prevalence of tinea unguium among females and a peak incidence in ages 21-40 years.
  • * Trichophyton rubrum was the leading cause of dermatophytosis, while M. canis was primarily responsible for tinea capitis; the study also noted an increase in zoophilic dermatophytes in tinea faciei and tinea corporis.
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Multifactorial analysis of risk factors for foot ulcers in patients with neurovascular complications of diabetes.

Front Endocrinol (Lausanne)

October 2024

Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Precision Anaesthesia and Perioperative Organ Protection, Guangzhou, Guangdong, China.

Background: Diabetic foot ulcers (DFU) are a major complication associated with significant morbidity and mortality. While numerous studies have investigated risk factors for these ulcers in general, few have focused specifically on patients with Neurovascular Complications of Diabetes. This study aimed to evaluate the prevalence and risk factors for DFU in this specific population.

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  • Superficial fungal infections are common in Finland but often lead to delayed diagnoses due to their varied symptoms.
  • A study of patients treated from 2010 to 2021 at Oulu University Hospital found most cases involved older adults, with a notable increase in infections starting in 2017.
  • The most frequent infection was tinea pedis (athlete's foot), with many patients experiencing significant delays in referrals and diagnoses.
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  • Onychomycosis is a fungal infection affecting nails, and while oral antifungals are the main treatment for severe cases, the topical solution efinaconazole (10%) is effective and safe for mild to moderate infections, approved for ages 6 and up.
  • The literature review highlights efinaconazole's pharmacokinetics, safety, and effectiveness across different populations, including children, diabetics, and the elderly, showing no systemic side effects or drug interactions.
  • Efinaconazole is particularly beneficial for certain groups, such as females, children, early-stage infections, and those with mild nail involvement, making it a viable option, especially in cases of terbinafine resistance.
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  • The study aimed to explore the relationship between clinical and histological diagnoses and patch test results in patients with foot skin conditions at a medical college in India.
  • A cross-sectional analysis involved 44 patients, focusing on detailed examinations, KOH mounts, skin biopsies, and patch tests to confirm diagnoses.
  • The findings revealed allergic contact dermatitis as the most common diagnosis, with patch testing showing high sensitivity (90.91%) for detecting this condition, indicating that histopathological evaluation is critical for accurate diagnosis of foot dermatoses.
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  • * A study of 100 Danish pharmacies revealed that 99% recommended terbinafine as the first-line treatment, but 88% of employees were unaware of antifungal resistance issues.
  • * The findings highlight a need for better awareness among pharmacy staff regarding antifungal resistance to ensure effective treatment and prevent its spread.
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  • The study focused on the effectiveness of short-term oral fosravuconazole (F-RVCZ) therapy in treating tinea pedis (athlete's foot), administering it for either 1 week or 4 weeks depending on the type of infection.
  • Efficacy was assessed at multiple time points after treatment, showing an increase in effectiveness as time progressed, with favorable results for both interdigital/vesicular and hyperkeratotic tinea pedis.
  • Adverse reactions were minimal and manageable, suggesting that F-RVCZ may be as effective or superior to existing treatments like terbinafine and itraconazole in Japan.
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  • * Developing an mRNA-based vaccine for tinea cruris is proposed as a way to provide long-term immunity, reduce reliance on antifungal medications, and tackle issues like antifungal resistance.
  • * The study involves identifying potential protein candidates for the vaccine using reverse vaccinology, mapping immunogenic epitopes, and formulating a multitope mRNA vaccine with selected effective components to stimulate immunity.
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  • Diabetes Mellitus (DM) leads to serious complications such as diabetic foot ulcers (DFU) and diabetic foot infections (DFI), increasing the risk of limb amputation and death.
  • * Superficial fungal infections like tinea pedis and onychomycosis heighten the risk of DFU and DFI in diabetic patients.
  • * The article emphasizes the importance of dermatologists in a multidisciplinary team to screen and manage these fungal infections, aiming to mitigate complications associated with diabetic foot health.
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  • Psoriasis is a chronic inflammatory skin condition that presents with distinct silvery plaques, commonly appearing on areas like the scalp, elbows, and knees, affecting both sexes equally.
  • Two cases are presented where patients were misdiagnosed with tinea pedis (athlete's foot) but actually had psoriasis after failing to respond to standard antifungal treatments.
  • The first patient improved with steroid cream, while the second, who was non-compliant with treatment, developed a serious infection (cellulitis) due to untreated psoriasis.
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  • Skin diseases are common worldwide and significantly impact individuals' health-related quality of life (HRQoL), which goes beyond just physical symptoms.
  • A study conducted in Asmara, Eritrea, assessed the HRQoL of 375 dermatology outpatients using the Skindex-29 tool, revealing that over half experienced severely impaired overall HRQoL, particularly in emotional aspects.
  • Factors like living in rural areas and having chronic illnesses were linked to poorer HRQoL, emphasizing the need for tailored treatments that address patients' real needs.
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  • - Tinea infections, except for tinea versicolor, are caused by dermatophytes, with diagnosis often confirmed through potassium hydroxide preparation or other methods.
  • - Treatment varies by the type of tinea; topical drugs are effective for most, while oral medications are necessary for tinea capitis and often preferred for onychomycosis, pending diagnosis confirmation.
  • - Warts are typically treated with methods like cryotherapy or immune stimulants, while scabies requires treatment for both affected individuals and close contacts, using topical permethrin or oral ivermectin.
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Background: Tinea pedis, commonly known as athlete's foot, is a fungal infection affecting the skin of the feet, primarily between the toes. Despite being a common condition, there may be gaps in knowledge and practices regarding its transmission, risk factors, and treatment options among the general population.

Methods: This study adopted a cross-sectional research design.

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  • Onychomycosis, a fungal nail infection, is common in adults with diabetes mellitus (DM), and a study used genetic data to investigate its causal relationship with DM.
  • Methods included identifying cases of onychomycosis and various tinea infections through electronic health records and analyzing genetic data from a diabetes genome-wide study.
  • The findings indicate that genetic risk for Type 2 diabetes (T2DM) positively influences the likelihood of developing onychomycosis, while no significant link was found with tinea infections, suggesting the need for diabetes patients to be screened for this nail infection.
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Interdigital-type antifungal socks for prevention and treatment of tinea pedis.

J Infect Public Health

July 2024

Department of Dermatology and Marine Biological Injuries, Naval Medical Centre, Naval Medical University, Shanghai 200052, China. Electronic address:

Article Synopsis
  • Interdigital tinea pedis is the most common foot infection, often treated with antifungals, but resistance is rising, making antifungal socks a promising new option.
  • A study tested these antifungal socks, comparing their effectiveness against regular socks in both preventing and treating tinea pedis by measuring symptoms.
  • Results showed that the antifungal socks had strong in vitro antifungal properties, significantly reduced symptoms in patients, and had a 72.9% effectiveness rate in alleviating tinea pedis symptoms compared to plain socks.
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Retrospective Analysis of Onychomycosis Risk Factors Using the 2003-2014 National Inpatient Sample.

Dermatol Pract Concept

April 2024

Weill Cornell Medicine, Department of Dermatology, New York, NY, USA.

Article Synopsis
  • Onychomycosis, a fungal nail infection, significantly affects patients' quality of life, and identifying related risk factors can help develop better screening guidelines.
  • The study analyzed data from the National Inpatient Sample (2003-2014) to explore demographic and health-related factors in over 119,000 onychomycosis cases compared to more than 239,000 controls.
  • Results showed that onychomycosis patients were more likely to be Black, insured by Medicare or Medicaid, had longer hospital stays and higher medical costs, and were frequently associated with other health issues like tinea pedis and HIV.
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pH- and Matrix Metalloproteinase-Responsive Multifunctional Bilayer Microneedles Platform for Treatment of Tinea Pedis.

ACS Biomater Sci Eng

May 2024

Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou 510006, China.

Persistent foot odor and itchiness are common symptoms of tinea pedis, significantly disrupting the daily life of those affected. The cuticular barrier at the site of the tinea pedis is thickened, which impedes the effective penetration of antifungal agents. Additionally, fungi can migrate from the skin surface to deeper tissues, posing challenges in the current clinical treatment for tinea pedis.

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  • - Secondary bacterial infections commonly occur in skin conditions like atopic dermatitis, ectoparasitosis, and varicella zoster, primarily involving Staphylococcus aureus and Streptococcus pyogenes, with occasions of Gram-negative infections as well.
  • - Factors that promote these infections include changes to the skin barrier, itchiness, and specific environmental influences, which can vary based on the patient's location and the type of dermatosis.
  • - Effective prevention and treatment hinge on managing the underlying skin condition, maintaining proper skin hygiene, and in cases of recurrence, addressing S. aureus colonization.
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  • * Analyzing patient records from a dermatology clinic over 12 years, the research found that only 1.8% of confirmed dermatophytosis cases were due to E. floccosum, with male and female patients equally affected.
  • * The study noted a steady decline in E. floccosum infections, even though tinea pedis, tinea cruris, and tinea corporis remained the most common types of infections throughout the period.
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Background: Dermatomycoses count to the most frequent dermatoses in Cambodia.

Objectives: The aim of this survey was to investigate the occurrence of dermatophytes in this Southeast Asian country.

Methods: From June 2017 to July 2018, skin scrapings were taken from 67 patients with superficial dermatophytosis for mycological diagnostics.

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