4 results match your criteria: "Tianjin University of Chinese Traditional Medicine[Affiliation]"
New verticillane-diterpenoid as potent NF-κB inhibitor isolated from the gum resin of Boswellia sacra.
Fitoterapia
April 2023
School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, People's Republic of China. Electronic address:
Two new verticillane-diterpenoids (1 and 2) were isolated from the gum resin Boswellia sacra. Their structures were elucidated by physiochemical and spectroscopic analysis, as well as ECD calculation. In addition, the in vitro anti-inflammatory activities of the isolated compounds were evaluated by determining the inhibitory effects on lipopolysaccharide (LPS)-induced NO production in RAW 264.
View Article and Find Full Text PDFMultifunction of the ER P-Type Calcium Pump Spf1 During Hyphal Development in Candida albicans.
Mycopathologia
October 2019
Key Laboratory of Molecular Microbiology and Technology, Department of Microbiology, Ministry of Education, College of Life Science, Nankai University, Tianjin, 300071, People's Republic of China.
Candida albicans is one of the most important fungal pathogens. Hyphal development is required for the virulence of this pathogen. Our previous study has revealed that Spf1, an ER P-type calcium pump, plays an important role in hyphal development.
View Article and Find Full Text PDFExpression of aldosterone synthase CYP11B2 was inversely correlated with longevity.
J Steroid Biochem Mol Biol
July 2019
Department of Uro-Oncology, Saitama Medical University International Medical Center, Saitama, Japan; Department of Biochemistry, Keio University School of Medicine, Tokyo, Japan. Electronic address:
Immunohistochemistry of human aldosterone synthase (CYP11B2) has revealed that most of aldosterone is autonomously produced in aldosterone-producing cell clusters (APCCs) beneath the capsule of adult adrenals rather than physiologically in the zona glomerulosa (ZG). APCCs have been occasionally found to harbor a somatic mutation of ion channel/pump genes, and number and size of APCCs increase with age until 50 years old. Herein, the objective of the study was to examine APCC development in 106 autopsied adrenals from 85 elderly individuals who died at ages from 50 to 103 years.
View Article and Find Full Text PDF[Study on methodology of determination of Yizhi osmotic pump tablets active ingredient in Beagle dog plasma by LC-MS/MS].
Zhongguo Zhong Yao Za Zhi
July 2011
Tianjin University of Chinese Traditional Medicine, Tianjin 300193, China.
Objective: To develop a sensitive and specific LC-MS/MS method for determination of Yizhi osmotic pump tablets active ingredient in Beagle dog plasma.
Method: Beagle dog plasma pre-treatment methods were established. Geniposide, notoginsenoside R1, ginsenoside Rg1 and Rb1 notoginsenoside molecular ions and fragment ions peaks were separated well and detected synchronously by LC-MS/MS with digoxin as internal standard.