2 results match your criteria: "Tianjin Medical University General Hospital Affiliated to Tianjin Medical University[Affiliation]"
CircZMYM2 Alleviates TGF-β1-Induced Proliferation, Migration and Activation of Fibroblasts via Targeting miR-199b-5p/KLF13 Axis.
Appl Biochem Biotechnol
January 2025
Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital Affiliated to Tianjin Medical University, No.154 Heping Road to Anshan, Tianjin City, 300052, People's Republic of China.
Dysregulated circular RNAs (circRNAs) has been revealed to be involved in pulmonary fibrosis progression. Herein, this study focused on exploring the function and mechanism of circRNA Zinc Finger MYM-Type Containing 2 (circZMYM2) on idiopathic pulmonary fibrosis (IPF) using transforming growth factor (TGF)-β1-stimulated fibroblasts. Human fibroblast cell lines IMR-90 and HFL1 were stimulated with TGF-β1 to mimic fibrosis condition in vitro.
View Article and Find Full Text PDFEffects of sitagliptin on serum lipid levels in patients with type 2 diabetes: a systematic review and meta-analysis.
J Cardiovasc Med (Hagerstown)
May 2022
Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University.
Article Synopsis
- The study examines how sitagliptin affects lipid control in diabetic patients, particularly regarding cholesterol levels.
- A meta-analysis of 14 randomized clinical trials involving 2,654 patients shows that sitagliptin treatment lowers total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) significantly.
- However, sitagliptin does not appear to have a notable impact on triglycerides or high-density lipoprotein cholesterol (HDL-C).