13,859 results match your criteria: "Thyroid Nodule"

Objective: To analyze the efficacy of the S-Detect AI system of the Samsung RS85 ultrasound scanner (South Korea) in stratifying thyroid nodules compared to data obtained by specialist of ultrasound diagnostics.

Material And Methods: In 2024, we analyzed ultrasound data of 80 patients with thyroid nodules who required fine-needle aspiration biopsy (FNAB). Patients underwent thyroid ultrasound with nodule assessment according to the EU TI-RADS classification (GE Voluson E8 scanner, USA).

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Ultrasound-guided thermal ablation (TA) is a minimally invasive intervention for treating benign thyroid nodules (BTNs). This meta-analysis aims to systematically compare the safety and efficacy of ultrasound-guided TA with surgery in treating BTNs. Relevant studies were identified through searching electronic databases.

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BACKGROUND We present a rare case of an ectopic thyroid nodule hyperplasia, confirmed postoperatively after excision and histopathological examination of a chronic cervical mass. We discuss the different clinical and therapeutic features of this rare thyroid dysgenesis caused by a defect of migration of the gland along its normal way of descent. CASE REPORT A 48-year-old man with a history of hypertension and asthma presented with dysphagia and a progressively growing firm mass at the anterior part of his neck over the past 6 months.

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Article Synopsis
  • This pilot study assesses the effectiveness of the Koios Decision Support™ AI tool in improving the accuracy of ultrasound evaluations for thyroid nodules, aiming to reduce the need for fine needle aspiration (FNA).
  • Conducted on 29 patients analyzed over a year, the study compared traditional FNA results with AI recommendations, using surgical histology as a standard reference.
  • The findings indicate that while the AI tool has a sensitivity of 85.7% and a positive predictive value of 63.2%, it also suggests that 53% of benign cases may not need FNA, highlighting the potential for AI to enhance diagnostic performance despite the sample size limitations.
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This study evaluates the clinical efficacy of microwave ablation in patients with benign thyroid nodules based on contrast-enhanced ultrasound. A total of 92 patients with benign thyroid nodules admitted to our hospital from January 2020 to December 2022 were selected as research subjects and divided into control group and observation group according to different treatment methods, with 46 cases in each group. All patients received microwave ablation.

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In the thyroid, abnormal growth can be the result of either benign thyroid nodules (BTNs) or differentiated thyroid cancers (DTCs). If the growth is confirmed to be a DTC, surgical intervention, either a partial or total thyroidectomy, is recommended. Although a majority of BTNs do not require treatment, intervention becomes necessary when nodules cause symptoms, enlargement, or a rare suspicion of malignancy.

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An Incidental Finding of Concomitant Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma: A Case Report.

Cureus

November 2024

Department of Internal Medicine, Division of Endocrinology, Ministry of National Guard-Health Affairs, Jeddah, SAU.

Concomitant medullary thyroid carcinoma and papillary thyroid carcinoma in the thyroid gland are rare; however, the incidence is increasing. Here, we present the case of a 77-year-old male who was incidentally found to have thyroid nodules after a road traffic accident. Fine-needle aspiration revealed two inconclusive Bethesda classifications: follicular neoplasm and unsatisfactory.

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Background: Accurately diagnosing thyroid nodules is vital for preventing unnecessary surgeries and providing prompt therapy. Although fine-needle aspiration cytology (FNAC) and ultrasonography (US) are widely used diagnostic methods, their reliability is questioned. This study investigates the effectiveness of US and FNAC in thyroid nodule diagnosis and differentiates benign from malignant nodules in relation to final histopathological diagnosis.

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Article Synopsis
  • The study examines thyroid tumors with isolated RAS mutations, comparing their oncologic outcomes to tumors with isolated BRAF mutations using comprehensive molecular testing.
  • A total of 368 patients with Bethesda III-VI thyroid nodules were reviewed, revealing that 14% had isolated RAS mutations, with a 46% malignancy rate but no instances of structural recurrence after 5 years.
  • The findings suggest that isolated RAS-mutated tumors have lower aggressive characteristics, indicating that thyroid lobectomy may be an adequate treatment option for these patients.
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[Use of clinical ultrasound in primary care: Thyroid nodule].

Semergen

December 2024

Medicina Familiar y Comunitaria, Centro de Salud Don Benito Oeste, Don Benito, Badajoz; Miembro del Grupo de Trabajo de Ecografía de SEMERGEN, España.

The thyroid nodule is a frequent lesion within the thyroid. Its incidence is between 50%-60% and most of them are asymptomatic and benign (90-95%) and its diagnosis is frequently made as an incidental finding. The main objective of their study is to rule out thyroid cancer.

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This article presents a dataset containing 641 images of Thyroid Gammagraphies studies corresponding to 235 patients over 18 years of age that were acquired in the period from 2016 to 2024 at the Nuclear Medicine Service of the of the (IICS - UNA), Paraguay. First, the Thyroid Gammagraphies images were acquired according to the acquisition protocol described in this article. The thyroid scintigraphies images were acquired using trimodal SPECT-CT-PET equipment, model AnyScan SCP, MEDISO brand.

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Introduction: Shear wave elastography (SWE) is an ultrasound diagnostic method used to measure tissue stiffness. Since the mechanical properties of tissue involved in the pathological process change, SWE might indicate regions of the examined tissue covered by the disease. It is well documented that SWE helps to differentiate benign and malignant nodules in thyroid glands in adults, however, there are few studies on the application of SWE in thyroid diagnosis in children.

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Background: Solitary fibrous tumors (SFT) are ubiquitous mesenchymal neoplasms of intermediate malignant potential. SFTs of the head and neck are rare, representing less than 0.1% of all SFTs.

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Objective: Tumor necrosis factor alpha inhibitors are frequently used in the treatment of axial spondyloarthritis. While tumor necrosis factor alpha is associated with some malignancies, studies on its effects on thyroid functions and thyroid nodules are limited. This study aimed to assess the effect of tumor necrosis factor alpha inhibitors treatments on the evaluation of thyroid nodules and thyroid function tests in axial spondyloarthritis patients.

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Afirma Genomic Sequencing Classifier (GSC) testing has been utilized for further risk stratification of thyroid nodules categorized as atypia of undetermined significance (AUS). The 2023 Bethesda system subcategorizes AUS diagnosis into AUS with nuclear atypia (AUS-N) and other atypia (AUS-O). The current study aims to determine if performance of GSC testing differs between the two AUS subcategories and between single AUS cohort and repeat AUS cohort.

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Clinical management of indeterminate thyroid nodules needs to be revisited. New evidence for a personalized approach to the problem.

J Endocrinol Invest

December 2024

Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi Nesima Hospital, University of Catania, Catania, Italy.

Purpose: Thyroid nodules diagnosed by fine needle aspiration cytology (FNAC) as TIR3A or Class III subgroup "other types of atypia" (indeterminate thyroid nodules - ITNs), are the only ones without a unique clinical action indicated for management. This leads to multiple FNAC repetitions (FNAC-reps) and lifelong follow-up, with huge consumption of time and resources. The aims of the study were to inquire the usefulness of repeating FNAC in ITNs and perform an evaluation of a long-term follow-up of a large cohort of ITNs.

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Aim: The British Thyroid Association (BTA) Guidelines for the Management of Thyroid Cancer advocate for fine-needle aspiration cytology for all thyroid nodules graded indeterminate (U3) at ultrasound assessment. This approach raises concerns regarding potential over-diagnosis of low-risk lesions. Conversely, equivalent Thyroid Imaging Reporting and Data Systems (TIRADS) guidelines permit surveillance or discharge of indeterminate thyroid nodules of certain sizes.

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Article Synopsis
  • The study evaluated a multivariate regression model that uses ultrasound findings and serum markers to predict thyroid cancer metastasis among 98 patients.
  • It categorized patients into two groups: those with metastasis (20 patients) and without (78 patients), and examined various indicators for their predictive value.
  • Results showed that a combination of ultrasound signs and serum markers significantly improved prediction accuracy, highlighting the model's potential for enhancing early detection and intervention in thyroid cancer cases.
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Thyroid Hormone Resistance With a Novel Mutation.

Cureus

November 2024

Radiology, Dubai Health Authority, Dubai, ARE.

Syndrome of thyroid hormone resistance (THR) is a rare inherited condition characterized by a reduced responsiveness of the tissues to the thyroid hormone. The syndrome is caused primarily by mutations in the thyroid hormone receptor beta (THRB) gene, leading to impaired hormone receptor function. It is a diagnosis of exclusion and often leads to delays in establishing the diagnosis.

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[Application of 9-gene panel in assisting fine needle aspiration cytology to diagnose thyroid cancer].

Zhonghua Zhong Liu Za Zhi

November 2024

Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100021, China.

Article Synopsis
  • The study investigates the effectiveness of a 9-gene panel for diagnosing thyroid nodules that have indeterminate cytological results, compared to traditional BRAF V600E single-gene detection.
  • Researchers analyzed 579 thyroid nodule samples from patients, using next-generation sequencing to identify mutations in nine specific genes associated with cancer.
  • The results showed that 47.5% of tested nodules had mutations, with a majority of identified malignant cases linked to the BRAF gene, demonstrating the panel's potential as a diagnostic tool alongside standard cytology methods.
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Article Synopsis
  • The article DOI: 10.3389/fendo.2021.686849 has been revised for accuracy.
  • This correction aims to address errors or clarifications in the original text.
  • Readers are encouraged to refer to the updated version for the most accurate information.
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Article Synopsis
  • Ultrasonography and Strain Elastography are crucial for diagnosing thyroid lesions in children, who have a higher risk of malignancy than adults, thus often requiring a fine-needle aspiration biopsy (FNAB).
  • A study analyzing 123 FNABs in children with thyroid nodules showed that 19 were malignant, 5 were low-risk tumors, and the rest were benign, with significant differences observed in Strain Ratio (SR) values across these groups.
  • The results indicated a clear distinction in SR values between malignant and both benign and low-risk tumors, highlighting the importance of elastography in evaluating the risk of thyroid nodules in pediatric patients.
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Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a rare thyroid malignancy typically linked to chronic lymphocytic thyroiditis. We present the first documented case of SMECE in Georgia, involving a 41-year-old woman with Hashimoto's thyroiditis. A 16 mm hypoechoic thyroid nodule was detected on routine ultrasound, and fine needle aspiration categorized it as Bethesda V.

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