457 results match your criteria: "Thyroid Evaluation of Solitary Thyroid Nodule"

Autonomously functioning thyroid nodules (AFTNs) represent ∼5% of all thyroid nodules and often necessitate definitive treatments such as surgery or radioiodine (I), both of which have inherent risks. Radiofrequency ablation (RFA) has emerged as an effective and safe therapeutic option for managing AFTNs. This study aims to assess the effectiveness and safety of RFA for solitary AFTNs in various countries across Latin America.

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Article Synopsis
  • A study conducted at Jinnah Postgraduate Medical Center explored the prevalence of thyroid disorders, finding that out of 258 patients, a significantly higher percentage were females (74.4%) compared to males (25.6%).
  • The research revealed that solitary nodules were the most common local examination finding, with benign follicular lesions being the most prevalent type of thyroid pathology.
  • The study concluded that increased screening and access to healthcare services are crucial due to the higher prevalence of thyroid disorders in females, particularly those with multinodular goiter presentations.
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Introduction: Thyroid diseases affect approximately 42 million people in India. The majority (15%-40%) of these cases remain asymptomatic and benign and warrant special investigations such as ultrasonography (USG) and fine-needle aspiration cytology (FNAC) for diagnosis. Early diagnosis and management of thyroid disorders determine the disease course in many patients.

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Thyroid nodular disease can present in different forms, such as a solitary nodule, multinodular goiter, nodular goiter caused by autoimmune goiter, and nonpalpable thyroid nodules. Among children, thyroid cancer is the most common type of endocrine cancer. Pediatric thyroid cancer is usually detected as a neck mass without any symptoms, leading to variable stages of progression when diagnosed.

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Background Acromegaly is a rare disease that is frequently associated with thyroid diseases. The exact prevalence of goiter and thyroid dysfunction remains uncertain. Objectives This study aims to provide a comprehensive description of the clinical, morphological, and biochemical features of thyroid disorder in Saudi patients with acromegaly and to establish its correlation with the activity and duration of the disease.

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We present a case of a patient with simultaneous cervical lymph node metastasis of papillary thyroid cancer (PTC) and cecum neuroendocrine tumor (NET). A 45-year-old male patient with the diagnosis of metastatic NET of the cecum underwent fine needle aspiration (FNA) of a positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG PET) positive nodule in the left thyroid lobe. Due to FNA finding suspect of PTC, the patient underwent total thyroidectomy with central neck dissection.

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Physical Examination of the Thyroid: Accuracy in Detecting Thyroid Nodules and Frequency of Additional Findings.

Endocr Pract

January 2024

Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, Minnesota; Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address:

Article Synopsis
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Thyroid nodules are exceedingly common in the general population and their increasing incidence appears to be secondary to incidental finding on imaging. Nonetheless, due to the potential for malignancy and thyroid dysfunction, most thyroid nodules require further investigation. Although there are no current guidelines for thyroid cancer screening in asymptomatic patients, a thorough history and physical which focuses on risk factors can serve as a good starting point during the evaluation of a thyroid nodule.

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Risk Factors for Malignancy in Patients with Multinodular Goiter.

Int Arch Otorhinolaryngol

January 2023

Surgery Department, Faculdade de Medicina da USP, São Paulo, SP, Brasil.

 The identification of thyroid cancer may be conducted through clinical detection, imaging method, and histopathological examination. Both solitary nodules and multinodular goiter are associated with malignancy.  To assess the risk factors for malignancy among patients with multinodular goiter submitted to total thyroidectomy.

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Identifying and Predicting Diverse Patterns of Benign Nodule Growth.

J Clin Endocrinol Metab

June 2023

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA 02115, USA.

Article Synopsis
  • The study examines the growth patterns of benign thyroid nodules in 389 patients over an average follow-up of 7.7 years, revealing three distinct growth rates: stagnant, slow-growing, and fast-growing.
  • Fast-growing nodules occur more frequently in younger patients and larger nodules, with 17.2% of nodules falling into this category.
  • An increase in nodule size during the first three years serves as a strong predictor for continued fast growth in the long term, despite the majority of nodules showing minimal growth over time.
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Cost-effectiveness analysis of molecular testing for cytologically indeterminate thyroid nodules.

J Otolaryngol Head Neck Surg

December 2022

Section of Otolaryngology, Department of Surgery, University of Calgary, Foothills Medical Centre, North Tower Rm 1012, 1403 29 St NW, Calgary, AB, T2N2T9, Canada.

Article Synopsis
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Diagnostic Efficacy of Thyrotropin to Thyroglobulin Ratio in Correlation with Histopathology of Euthyroid Patient Having Solitary Thyroid Nodule.

Indian J Otolaryngol Head Neck Surg

October 2022

Department of Otorhinolaryngology, SMS Medical College, C168E, Street No. 2, Khadi Colony, Bajaj Nagar, Jaipur, Rajasthan 302015 India.

In patients with solitary thyroid nodules, the first course of action is to determine whether the nodule is benign or malignant. Many investigations are used to differentiate between benign and malignant nodules so as to avoid surgery in those who don't need it. Among these, FNAC and USG are commonly used in association with clinical features but there are drawbacks of each technique.

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It is uncertain whether the presence of autoimmune thyroiditis (AIT) increases the risk of thyroid cancer in children with thyroid nodules. This study evaluated the association between AIT and thyroid cancer in pediatric patients with thyroid nodules. A cross-sectional study was performed of pediatric patients (<19 years old) with a thyroid nodule (≥1 cm) who underwent fine-needle aspiration in an academic pediatric thyroid center.

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Objective: Thyroid dermopathy (TD), reportedly encountered in less than 5% of patients with Graves' disease (GD), is supposed to coexist only with thyroid-associated orbitopathy (TAO). However, clinically inapparent TD, detected non-invasively by thermal imaging or ultrasonography, seems to be present in a larger proportion of GD. Histopathological examination (HPE), though considered as gold standard for detecting TD, has not been performed widely to identify subclinical TD in GD.

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Article Synopsis
  • - This study compares traditional thyroid examination methods with the new modified Rose method, assessing how the experience level of the examiner affects clinical findings compared to ultrasound.
  • - Conducted with 83 patients at a hospital, the research involved both a trained Junior Resident and a Surgery Consultant examining patients using multiple methods and analyzing the results statistically.
  • - Findings suggest that the modified Rose method is highly sensitive for identifying certain thyroid conditions, while Lahey's method is superior for examining cervical lymph nodes, highlighting differences in effectiveness among the various techniques.
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Objective: Distant metastases from papillary thyroid carcinoma (PTC) are relatively rare and may be associated with a poor prognosis. The adrenal gland is a highly unusual site of metastasis in the natural course of PTC. Herein, we describe a case of an incidentally detected metastatic solid variant of PTC in the adrenal gland of an asymptomatic patient as the initial presentation.

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Efficacy in size and symptom reduction of radiofrequency ablation of benign non-functioning thyroid nodules.

Endocrinol Diabetes Nutr (Engl Ed)

March 2022

Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Av. Roma, s/n, 33011 Oviedo, Asturias, Spain; Grupo de investigación en Endocrinología, Nutrición, Diabetes y Obesidad, Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain.

Article Synopsis
  • Radiofrequency ablation (RFA) is an effective treatment for reducing the size and symptoms of benign thyroid nodules, showing significant volume reductions over one year.
  • The study reviewed 72 patients who underwent RFA, measuring changes in nodule size, compressive and cosmetic symptoms, while monitoring thyroid function.
  • Results showed statistically significant improvements in both nodule size and patient-reported symptoms, with no major complications reported, supporting RFA as a safe and viable option for management.
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Predictors of Malignancy in Thyroid Nodules.

Mymensingh Med J

April 2022

Dr Md Rafiqul Islam, Associate Professor, ENT and Head Neck Surgery, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

Thyroid swellings are common clinical problem throughout the world and also in Bangladesh. Most of thyroid swellings are multinodular, but a good percentage is solitary thyroid nodule. There is no robust, feasible method for malignancy differentiation has not been well established.

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