24,944 results match your criteria: "Thrombophlebitis"

An unusual case of high gastrointestinal bleeding after Whipple surgery.

Acta Gastroenterol Belg

October 2024

Department of Gastroenterology and Hepatology, AZ Diest, Diest, Belgium.

Pancreatic cancer is an aggressive malignancy with poor survival rates. Pancreatic surgery has improved outcomes in the last few decades, but still contains high morbidity rates. Pancreatic fistula, delayed gastric emptying, intra-abdominal infections and bleeding are well-known complications.

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  • The study aimed to assess microcirculation abnormalities in patients with Behçet's Syndrome (BS) and their link to vascular issues using nailfold videocapillaroscopy (NVC).
  • Out of 65 patients, 36.9% showed vascular involvement, with NVC revealing abnormalities like tortuous capillaries and microhaemorrhages in nearly half of the participants.
  • Significant correlations were found between specific NVC abnormalities and vascular complications, indicating that NVC could be useful for early identification of patients at risk for vascular events.
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  • Infective endocarditis (IE) includes rare cases like Eustachian valve endocarditis (EVE), which can occur in patients without typical risk factors, as demonstrated in a 66-year-old male.
  • The patient showed various symptoms and complications, such as liver abscesses and spinal osteomyelitis, leading to the confirmation of EVE through transesophageal echocardiography (TEE) and blood cultures.
  • Successful treatment involved antimicrobial therapy, drainage of abscesses, and anticoagulation, highlighting the need for awareness of atypical endocarditis forms for timely diagnosis and management.
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Lemierre's syndrome associated-diabetic ketoacidosis in an elderly female: a case report.

BMC Infect Dis

October 2024

Department of Emergency Medicine, Division of Life Science and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230001, China.

Article Synopsis
  • - A 69-year-old female developed diabetic ketoacidosis (DKA) due to a deep neck space infection, a rare instance of Lemierre's syndrome, which is usually triggered by oropharyngeal infections from Fusobacterium necrophorum.
  • - The patient's condition worsened rapidly, leading to high flow nasal cannula support and aggressive antibiotic treatment; lab results showed signs of severe infection and metabolic issues.
  • - Successful management involved fluid resuscitation, insulin therapy, surgical intervention, and anticoagulation, resulting in significant improvement and her eventual discharge after 13 days in the hospital.
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Article Synopsis
  • Lemierre syndrome involves septic thrombophlebitis of the internal jugular vein (IJV) and infection spread after an oropharyngeal infection, while Lemierre-like syndrome occurs without a recent oropharyngeal infection and can be caused by non-Fusobacterium bacteria.
  • A case study reports an infant with Lemierre-like syndrome caused by Enterobacter cloaca bacteremia, presenting symptoms of cough, fever, and respiratory distress, but with no known prior throat infection.
  • Imaging showed thrombosis in the IJV and superior vena cava, along with lung and liver abscesses; treatment included antibiotics and draining the abscesses, leading to the infant's recovery.
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  • A 53-year-old man developed this condition after engaging in extended sexual activity the night before, while also using sildenafil.
  • An ultrasound confirmed the diagnosis, showing thrombosis in the vein and swelling, and he received conservative treatment; the case emphasizes the link between vigorous sexual activity, sildenafil use, and MD.
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Cerebral venous thrombosis in elderly patients.

Eur J Neurol

December 2024

Stroke Units and Department of Neurology of Hôpital Bicêtre, Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris, Paris Saclay University, Paris, France.

Article Synopsis
  • The study examined cerebral venous thrombosis (CVT) characteristics in elderly patients (65 years and older) across nine hospitals in the Paris-Ile-de-France region from 2011 to 2021.
  • Researchers found that the annual incidence of CVT in this demographic was lower compared to the national average, with headaches and focal deficits being the most common initial symptoms.
  • The results indicated that elderly patients had a distinct clinical profile, with higher rates of underlying conditions like cancer and a worse prognosis than younger adults, highlighting the need for specialized care in this age group.
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Role of Peripheral Parenteral Nutrition Composition on Clinical Outcomes in Patients Undergoing Gastrectomy or Colectomy: A Phase III Indian Clinical Trial.

Indian J Crit Care Med

September 2024

Department of Medical Affairs, Otsuka Pharmaceutical India Pvt. Ltd., Ahmedabad, Gujarat, India.

Article Synopsis
  • The study compares two parenteral nutrition solutions, BFLUID and NUTRIFLEX PERI, to assess their efficacy and safety for patients after abdominal surgeries like gastrectomy and colectomy.
  • It involved a multi-center clinical trial with 150 patients, focusing on hospital stay duration, ICU stay, and various adverse effects.
  • Results showed no significant differences between the two groups in terms of hospital stay, adverse events, or infection rates, confirming that BFLUID is a safe alternative to NUTRIFLEX PERI for post-surgery nutrition.
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Current Diagnostic and Therapeutic Challenges in Superficial Venous Thrombosis.

Medicina (Kaunas)

September 2024

Dr. Carol Davila University Central Military Emergency Hospital, "Carol Davila" University of Medicine and Pharmacy, Calea Plevnei 134, 010825 Bucharest, Romania.

Article Synopsis
  • * Risk factors for SVT include varicose veins, but other underlying issues like cancers or blood disorders may be present, especially in non-varicose veins.
  • * Diagnosis often requires duplex ultrasound (DUS) to determine the clot's characteristics, and treatment usually focuses on medical management, including anticoagulation and symptom relief, with more invasive approaches reserved for severe cases.
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  • The case report discusses a rare but serious condition called facial vein thrombophlebitis following a facial skin infection in a 33-year-old man with multiple health issues.
  • The patient presented with a small facial wound and swelling, which did not improve with topical treatment and led to fever.
  • Emergency management included fluid resuscitation and the administration of antibiotics, emphasizing the importance of early diagnosis and prompt treatment to avoid severe complications.
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Article Synopsis
  • * Imaging techniques showed the presence of the thrombus, and cultures taken during surgery identified the unusual pathogen involved.
  • * The treatment included intravenous antibiotics and anticoagulation, highlighting the need for awareness of rare pathogens in sinusitis-related thrombosis and advocating for a collaborative medical approach for complex cases.
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thrombophlebitis complicating cyanoacrylate closure procedure.

J Vasc Surg Cases Innov Tech

December 2024

Infectious Disease Service, Department of Medicine, Tripler Army Medical Center, Honolulu, HI.

Article Synopsis
  • * The cyanoacrylate closure (CAC) technique, particularly using the VenaSeal device, has become popular for its quicker recovery and fewer complications compared to traditional methods.
  • * A case study highlights a patient with diabetes who developed phlebitis after a CAC procedure, necessitating surgical removal of the affected vein and prolonged antibiotic treatment due to challenges with bacterial contamination in endovascular procedures.
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Article Synopsis
  • Lemierre's syndrome involves septic thrombophlebitis in the internal jugular vein and was observed in a 57-year-old woman with a history of untreated dental infection.
  • Upon examination, she exhibited increased blood pressure and a painful, swollen neck, which was confirmed by ultrasound and CT scan showing a thrombus in the right internal jugular vein.
  • Treatment primarily includes antibiotics; in this case, the patient was treated conservatively with both antibiotics and anticoagulants, leading to significant improvement in her condition.
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Isolated external jugular thrombophlebitis secondary to acute pharyngitis: a case report and a review of the literature.

Ital J Pediatr

September 2024

Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, NYU Langone Health, 240 East 38th Street 14th floor, New York, NY, 10016, USA.

Article Synopsis
  • External Jugular Thrombophlebitis (EJT) is a rare condition, especially in children, and this case report discusses a 13-year-old with right-sided EJT linked to acute pharyngitis and left-sided sinusitis.
  • The patient presented with worsening upper respiratory symptoms, facial swelling, and was diagnosed with sinusitis and external jugular vein thrombosis after imaging was conducted.
  • The treatment included IV antibiotics and anticoagulation, leading to improvement, and follow-up showed no recurrence of EJT, highlighting the importance of recognizing EJT symptoms in conjunction with respiratory infections.
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Article Synopsis
  • Systemic Lupus Erythematosus (SLE) often coexists with antiphospholipid syndrome, leading to blood clotting issues or complications in pregnancy, as illustrated by a case of a 7-year-old girl experiencing fever, bleeding, and thrombophlebitis.
  • The child presented with symptoms like gum bleeding, small skin lesions, and abnormal blood coagulation tests, prompting further investigation for an autoimmune disorder.
  • Ultimately, she was diagnosed with Systemic Lupus Erythematosus and Lupus Anticoagulant Hypoprothrombinemia Syndrome after confirming the presence of specific antibodies and coagulation abnormalities.
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Cerebral Thrombophlebitis Complicating Coeliac Disease.

Cureus

August 2024

Pediatric Gastroenterology, Abderrahim El Harouchi Hospital, Ibn Rochd University Hospital, Casablanca, MAR.

Article Synopsis
  • Thromboembolic complications, particularly abdominal venous thrombosis, are uncommon in coeliac disease, while cerebral thrombosis is very rare.
  • Investigating thrombotic risk factors in patients with coeliac disease is crucial for understanding potential complications.
  • A clinical case is presented involving a child with coeliac disease who developed cerebral thrombophlebitis linked to antithrombin III deficiency and anticardiolipin antibodies.
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Article Synopsis
  • Vascular complications from sphenoid sinusitis are uncommon because the mucosa and bone act as barriers, but certain conditions like dehiscence or aggressive infections can increase risks, potentially leading to severe issues like cavernous sinus thrombosis.
  • Untreated or severe cases of sphenoid sinusitis can result in serious neurological problems, including cerebral infarcts, meningitis, and cranial nerve injuries, which can be detected early with MRI and angiography.
  • A reported case of an 11-year-old boy illustrates these risks, as he experienced multiple complications from sphenoid sinusitis, including a cerebral artery infarct and various types of thrombosis due to associated mastoiditis.
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Article Synopsis
  • Venous aneurysms of the external jugular vein are rare due to low pressure in the venous system, and their exact occurrence rate is unclear.
  • These aneurysms usually appear as soft masses in the neck that can grow over time and may lead to complications like thrombosis or cosmetic issues.
  • Diagnosis is typically confirmed through Color Doppler ultrasound or CT angiography, as illustrated by a case of a congenital saccular pseudoaneurysm in a 58-year-old woman.
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Article Synopsis
  • Foot and ankle disorders are frequent during pregnancy due to changes in weight, hormones, and fluid balance, leading to issues like varicose veins, DVT, and tendon injuries.* -
  • Ultrasound is highlighted as a safe and non-invasive diagnostic tool, particularly effective for assessing venous conditions and differentiating causes of edema; it provides real-time imaging without radiation.* -
  • The technology also aids in diagnosing musculoskeletal problems and detecting foreign bodies, making it a cost-effective and accessible option for improving patient outcomes in pregnant women.*
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Article Synopsis
  • * A case involving a 33-year-old male with fever and sore throat revealed thrombosis in the jugular vein after a recent dental issue, leading to a diagnosis of Lemierre's syndrome.
  • * The case emphasizes the importance of considering Lemierre's syndrome in patients with similar symptoms, especially if they have a history of dental issues, and highlights the utility of metagenomic next-generation sequencing (mNGS) for difficult diagnoses.
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Article Synopsis
  • Fusobacterium necrophorum is a harmful bacterium that can cause serious infections in the throat, potentially leading to a severe condition called Lemierre's syndrome.
  • Researchers studied 70 strains of F. necrophorum, finding two main genetic groups: one linked to localized infections and another more common in cases of severe bacteremia.
  • A specific mutation in the lktA gene, along with other identified genetic factors, seems to play a role in the severity of infections, requiring further research to understand their impact on disease development.
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Article Synopsis
  • * A case study describes a 28-year-old man who experienced symptoms like coughing up blood and chest pain, along with complications seen via imaging, initially managed with high-dose corticosteroids and other immunosuppressants.
  • * The patient's condition relapsed after 18 months, but treatment with infliximab (a TNF-alpha inhibitor) led to complete remission, suggesting its potential as an effective second-line therapy for relapsing HSS cases.
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