Redox potentials of sulfonamide antibiotics mediating the electron transfer process in single-atom Cu catalyst/peroxymonosulfate system: Selective removal mechanisms for sulfonamides.

The oxidative behaviors of target pollutants in single-atom catalysts-activated peroxymonosulfate (SACs/PMS) system has mostly been studied from the loaded metal and coordination structure of SACs. However, the origin of the altered degradation behavior caused by the specific properties of pollutants has been neglected. Herein, Cu atoms coordinated with four N atoms embedded in biochar (Cu@C) was prepared to establish the relationship between the selective degradation behavior of sulfonamide antibiotics in Cu@C/PMS system and their own properties.

Mast Cells Contribute to Pressure Overload-Induced Myocardial Hypertrophy by Upregulating TRPV4 via Histamine: Role of Ca2+/ CnA/NFATc3 Signaling Pathway.

Objective: To investigate whether cardiac mast cells (MCs) participate in pressure overload-induced myocardial hypertrophy through the regulation of transient receptor potential vanilloid 4 (TRPV4).

Methods: Pressure overload-induced myocardial hypertrophy was induced via abdominal aortic constriction (AAC). Myocardial hypertrophy was evaluated by measuring the heart weight index (HW/BW), lung weight index (LW/BW), ratio of heart weight to tibia length (HW/TL), ratio of lung weight to tibia length (LW/TL), and cross-sectional area of myocardial cells.

Insights into closed-wet ultrasonic carbonation of MSWI fly ash: Carbon sequestration, heavy metals stabilization, and PCDD/Fs migration and degradation.

This study proposed a novel closed-wet accelerated carbonation method based on ultrasonic chemistry for treating municipal solid waste incineration fly ash (MSWI FA), assessing various reaction parameters (time, temperature, CO pressure, ultrasonic power, and alkaline additives) on the detoxification and synergistic carbon fixation. The mechanisms of carbon sequestration, heavy metal migration-stabilization, and PCDD/Fs migration-degradation were elucidated. Key findings include the reaction kinetic of MSWI FA ultrasonic carbonation aligning with the surface coverage model (R > 0.

Gentiopicroside Alleviates Atherosclerosis by Suppressing Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation in Vascular Endothelial Cells via SIRT1/Nrf2 Pathway.

Objective: To evaluate the protective effects of gentiopicroside (GPS) against reactive oxygen species (ROS)-induced NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation in endothelial cells, aiming to reduce atherosclerosis.

Methods: Eight-week-old male ApoE-deficient mice were randomly divided into 2 groups (n=10 per group): the vehicle group and the GPS treatment group. Both groups were fed a high-fat diet for 16 weeks.

Case Report: Efficacy of anlotinib and sintilimab in treating lung adenocarcinoma with RET fusion and PD-L1 expression.

We report a case of an advanced non-small cell lung cancer (NSCLC) patient with brain metastasis, RET fusion, and high expression of programmed death ligand 1 (PD-L1) at initial treatment. After receiving radiotherapy for the brain metastasis, the patient started with anlotinib and added immunotherapy with sintilimab. The patient had a good response to anlotinib and sintilimab treatment, tolerated the adverse reactions, and had a progression-free survival (PFS) of over 17 months.

A Scalable Pore-space-partitioned Metal-organic Framework Powered by Polycatenation Strategy for Efficient Acetylene Purification.

Efficient separation of acetylene (CH) from carbon dioxide (CO) and ethylene (CH) is a significant challenge in the petrochemical industry due to their similar physicochemical properties. Pore space partition (PSP) has shown promise in enhancing gas adsorption capacity and selectivity by reducing pore size and increasing the density of guest binding sites. Herein, we firstly employ the 2D→3D polycatenation strategy to construct a PSP metal-organic framework (MOF) Ni-dcpp-bpy, incorporating functional N/O sites to enhance CH purification.

Enhancing rejection of short-chain per- and polyfluoroalkyl substances by tailoring the surface charge of nanofiltration membranes.

Nanofiltration (NF) effectively removes per- and polyfluoroalkyl substances (PFAS) from water but struggles with short-chain PFAS (i.e., those containing less than 6 perfluorinated carbons) due to size exclusion inefficiency.

Does the establishment of civilized cities promote urban inclusive development?--Quasi-natural experiment based on the selection of "National Civilized City".

Taking the selection of "National Civilized City" as a quasi-natural experiment and basing on the research samples of 272 prefecture level and above cities in China from 2003 to 2020, this paper explores the impact of the establishment of civilized cities on urban inclusive development and its mechanism by using the time-varying DID model. The findings are as follows: firstly, the establishment of civilized cities has significantly promoted the urban inclusive development, and then parallel trend test, placebo test and other robustness tests verify the reliability of the research conclusions. Secondly, in regions with larger population, stronger financial strength and belonging to the Excellent Tourism City, the establishment of civilized cities has a more obvious role in promoting urban inclusiveness.

Multistage Regulation Strategy via Fluorine-Rich Small Molecules for Realizing High-Performance Perovskite Solar Cells.

Perovskite solar cells (PSCs) are an ideal candidate for next-generation photovoltaic applications but face many challenges for their wider application, including uncontrolled fast crystallization, trap-assisted nonradiative recombination, and inefficient charge transport. Herein, a multistage regulation (MSR) strategy for addressing these challenges is proposed via the introduction of fluorine-rich small molecules with multiple active points (i.e.

Total saponins from Panax japonicus mediate the paracrine interaction between adipocytes and macrophages to promote lipolysis in the adipose tissue during aging via the NLRP3 inflammasome/GDF3/ATGL axis.

Adipocytic lipolysis is strongly related to the increase of visceral fat, decrease of exercise capacity, and various other metabolic syndromes during aging. It is significantly influenced by the paracrine relationship between adipocytes and the adipose tissue macrophages (ATMs), and the cytokines secreted by ATMs have endocrine effects on adjacent tissues. We previously reported that the total saponins from Panax japonicus (TSPJs) can enhance lipid metabolism.

Solids retention time modulates nutrient removal in pilot-scale anaerobic-aerobic-anoxic process: Carbon allocation patterns and microbial insights.

Anaerobic-aerobic-anoxic (AOA) process is a promising configuration to retrofit current wastewater treatment plants with intensified carbon utilization and nutrient removal, but lacks process optimization for scaling-up in real wastewater scenarios. Solids retention time (SRT) is a fundamental parameter of activated sludge process, but its roles in the AOA process remain vague. Here, we established a pilot-scale AOA process at different SRTs (10, 20, 30 d) to investigate the comprehensive responses and potential mechanisms.

Predicting Futile Recanalization by Cerebral Collateral Recycle Status in Patients with Endovascular Stroke Treatment: The CHANOA Score.

Rationale And Objectives: The correlation between collateral circulation and futile recanalization (FR) is still controversial, and few studies have explored the influence of comprehensive cerebral collateral circulation on FR after endovascular stroke treatment. Therefore, based on cerebral collateral recycle (CCR) status, we aimed to establish an effective scoring system to identify the probability of FR.

Methods: This was a multicenter retrospective cohort study.

Interface gypsum deposition in flow-electrode CDI treating brackish water: Impacts and mechanisms.

Flow-electrode capacitive deionization (FCDI) is a promising electrically driven technology for brackish water desalination, but it suffers from scaling issues in the concentrate chamber when treating brackish water with high levels of SO and Ca. In addition, how the key components (e.g.

Advancement in surfactant-enhanced droplet deposition on the hydrophobic surfaces.

Droplets impacting solid surfaces are encountered in nature and industry, from rain to agricultural spraying and inkjet printing. Surfactants are an important factor that affects the impact behavior of droplets. An in-depth knowledge of the influence and mechanisms of surfactants on the dynamics of droplet impact can enhance the precise control of droplets in industrial processes.

Air-water exchange: Toxicities, risks and PAHs compounds in the three gorges reservoir of China.

Air-water exchange is inevitably accompanied by the transportation of contaminants between atmosphere and water, which significantly leads to the alterations of toxicity and risks. However, the resulting changes of toxicity and risk in water and air due to the cross-interfacial transport of pollutants are still unclear. In this study, the water and atmospheric samples at the Pengxi River located in the Three Gorges Reservoir (TGR), China, were collected in winter and summer seasons respectively.

Zinc oxide nanoparticles improve lactation and metabolism in dairy goats by modulating the rumen microbiota.

This study aimed to investigate the effects of dietary supplementation with zinc oxide nanoparticles (ZnONPs) on lactation, rumen microbiota, and metabolomics in dairy goats. Twenty Guanzhong dairy goats, with comparable milk yields and in the mid-lactation stage, were randomly divided into two groups, with 10 goats in each group. The control group was fed a standard diet, while the ZnONP group received the control diet plus 30 mg ZnONPs/kg DM.

Effect of different types of milk consumption on Crohn's disease and the mediating effect of amino acids: a Mendelian randomization study.

Dietary therapy is a common adjunctive treatment for Crohn's Disease (CD). However, previous studies had presented conflicting views on whether dairy products should be included in dietary therapy. This controversy may be due to confounding factors.

On three species of ctenids (Araneae: Ctenidae) from Tibet, China.

Three species of the spider family Ctenidae Keyserling, 1877 are recorded from Tibet of China, including two new species described here: Amauropelma medogensis sp. nov. (♂♀) and Bowie rotundus sp.

The wolf spiders of three national parks in Northern Vietnam (Araneae: Lycosidae).

Three wolf spiders (Lycosidae) from Northern Vietnam are described and illustrated, two of them being new species: Allotrochosina serpentina Wang & Li sp. nov. (♂♀) and Sinartoria hamata Wang & Li sp.

Review of the wolf spider genus Xerolycosa Dahl, 1908 from China (Araneae: Lycosidae).

The wolf spider of genus Xerolycosa Dahl, 1908 from China is reviewed, including four species: X. miniata (C.L.